Billing code 79101: Radiopharmaceutical therapyMedicare rate & RVUs

Report 79101 for therapeutic radiopharmaceutical delivered intravenously, with the record identifying the treatment, administered agent, route, and professional or technical work.

CMS RVU26DEffective Oct 1, 2026109 payment localities18.5K Medicare services in 2024

Medicare pays $142.96 for 79101 nationally in the office. Local office rates run $130.76–$182.24.

Medicare rate · 79101

Radiopharmaceutical therapy

Swap in your local Medicare rate.

Work RVUs
1.91
Total RVUs
4.28
Global days
XXX

National rate · 2026

$142.96

Office setting, before claim adjustments.

See every locality for 79101 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 79101 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 79101 covers

Code 79101 represents therapeutic delivery of a radiopharmaceutical through a vein. It is used when treatment requires intravenous administration rather than oral dosing or another delivery route. Nuclear medicine physicians and other qualified clinicians may provide the service in a hospital or outpatient nuclear medicine setting, with the radiopharmaceutical prepared and administered under appropriate clinical supervision. The treatment record should identify the agent, the therapeutic purpose, the intravenous route, and the administration performed.

Choose this code by the route of administration, not by the imaging used to assess the condition. Document the administered agent and activity, treatment date, and relevant administration details so the service can be distinguished from oral or nonintravenous therapy. CMS identifies separately priced professional and technical components: report modifier 26 for the professional interpretation and modifier TC for the technical portion involving equipment and staff. Report without either modifier for the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 79101 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$130.76 to $182.24

$130.76$156.50$182.24
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

79101 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$132.13Unavailable
Alaska*$178.45Unavailable
Arizona$140.16Unavailable
Arkansas$130.76Unavailable
Atlanta$144.97Unavailable
Austin$147.16Unavailable
Bakersfield$150.30Unavailable
Baltimore/Surr. Cntys$150.25Unavailable
Beaumont$135.89Unavailable
Brazoria$142.12Unavailable

79101 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$130.76

$178.45

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
79101 office rate range by state
State / territoryOffice rate rangeLocalities
AK$178.451
AL$132.131
AR$130.761
AZ$140.161
CA$149.96–$182.2429
CO$147.941
CT$150.731
DC$160.301
DE$142.061
FL$141.12–$150.673
GA$135.31–$144.972
GU$152.121
HI$152.121
IA$134.671
ID$135.281
IL$138.02–$147.784
IN$135.851
KS$134.151
KY$134.251
LA$134.07–$138.872
MA$147.40–$160.012
MD$144.26–$160.303
ME$135.73–$141.162
MI$136.72–$142.352
MN$143.051
MO$132.37–$139.313
MS$131.591
MT$142.951
NC$136.771
ND$141.171
NE$135.221
NH$145.701
NJ$152.81–$159.362
NM$137.241
NV$142.531
NY$138.26–$164.015
OH$136.351
OK$134.141
OR$141.76–$151.662
PA$136.55–$147.812
PR$143.751
RI$146.361
SC$136.721
SD$140.961
TN$134.631
TX$135.89–$147.168
UT$138.081
VA$140.78–$160.302
VI$143.751
VT$140.711
WA$147.10–$162.882
WI$137.681
WV$134.281
WY$142.171

How the 79101 rate is calculated

Each of 79101’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 79101

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.91Practice expense 2.28Malpractice 0.09

4.2800 adjusted RVUs×$33.4009 conversion factor=$142.96

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 79101

The CMS indicators that decide how 79101 is paid alongside other services.

CMS payment indicators · 79101

Radiopharmaceutical therapy

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

79101 without 26 · national office

$142.96

Radiopharmaceutical therapy

79101-26 · Professional component

$89.85

Pays only the interpretation and report.

When to use modifier 26

79101 compared with similar codes

Compare codes

79101 vs 79005 vs 79200: national Medicare rates

Swap in your local Medicare rate.

  • 79101
    Radiopharmaceutical therapy · 1.91 wRVU
    $142.96
  • 79005
    Radiopharmaceutical therapy · 1.76 wRVU
    $132.27−$10.69
  • 79200
    Radiopharmaceutical therapy · 1.94 wRVU
    $130.60−$12.36

How to choose

79005Radiopharmaceutical therapy
Use 79005 for oral radiopharmaceutical therapy. Use 79101 when the treatment agent is delivered intravenously.
79200Radiopharmaceutical therapy
79200 applies to intracavitary administration. Choose 79101 when the therapeutic agent is given through a vein.

79101 billing questions

How do I distinguish 79101 from oral radiopharmaceutical therapy?

Use 79101 when the therapeutic radiopharmaceutical is administered intravenously. Oral administration is represented by a different route-specific code.

Which modifiers identify the components?

Modifier 26 identifies the professional interpretation, and modifier TC identifies the technical portion involving equipment and staff. Without either modifier, the claim represents the global service.

What documentation supports 79101?

The record should identify the therapeutic agent, treatment purpose, intravenous route, administered activity, and date and details of administration.

Is 79101 selected by the drug or by the route?

Select it based on intravenous administration. The route distinguishes it from oral, intra-arterial, intracavitary, and other radiopharmaceutical therapy codes.

Does reporting 79101 without a modifier include both components?

Yes. CMS identifies an unmodified claim as the global service; modifiers 26 and TC separately identify the professional and technical portions.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 79101PPRRVU2026_Oct_nonQPP.csv, line 9,564 (RVU26D)

Open CMS sourceHow we calculate rates

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