CPT code 96413: Chemo IV infusion2026 Medicare rate & RVUs

Report the initial hour of intravenous antineoplastic or qualifying highly complex biologic infusion when the drug runs longer than 15 minutes.

CMS RVU26DEffective Oct 1, 2026109 payment localities1.7M Medicare services in 2024

Medicare pays $133.27 for 96413 nationally in the office. Local office rates run $114.99–$186.95.

Medicare rate · 96413

Chemo IV infusion

Office or facility?

Work RVUs
0.28
Total RVUs
3.99
Global days
XXX

National rate · 2026

$133.27

Office setting, before claim adjustments.

See every locality for 96413 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 96413 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 96413 covers

Code 96413 captures the initial hour of an intravenous antineoplastic infusion or an infusion of another agent that meets chemotherapy administration requirements for high-complexity biologic therapy. Oncology nurses commonly administer these treatments in physician offices or outpatient infusion suites under an oncologist’s or hematologist’s supervision. Paclitaxel or carboplatin infusions are familiar examples. Nursing work includes preparing the infusion, assessing the patient, monitoring for reactions, and ending the infusion; classification as a monoclonal antibody alone does not establish eligibility for chemotherapy administration coding.

Report one initial administration service per encounter unless separate medically necessary IV sites support distinct initial services. Record the drug and actual start and stop times; infusion lasting more than 15 minutes supports 96413, and 96415 begins only when the infusion exceeds 90 minutes. Sequential chemotherapy drugs and separately administered premedications or hydration may support additional administration codes when their requirements are met. The IV start, routine flush, and usual supplies are included; report separately payable drug products with appropriate HCPCS codes. CMS classifies 96413 as an incident-to service, billed only when performed under physician supervision.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 96413 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$114.99 to $186.95

$114.99$150.97$186.95
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

96413 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$117.06Unavailable
Alaska$144.80Unavailable
Arizona$129.16Unavailable
Arkansas$114.99Unavailable
Atlanta, GA$135.71Unavailable
Austin, TX$140.07Unavailable
Bakersfield, CA$144.20Unavailable
Baltimore area, MD$142.85Unavailable
Beaumont, TX$122.16Unavailable
Brazoria, TX$131.74Unavailable

96413 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$114.99

$165.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
96413 office rate range by state
State / territoryOffice rate rangeLocalities
AK$144.801
AL$117.061
AR$114.991
AZ$129.161
CA$144.02–$186.9529
CO$140.651
CT$143.311
DC$155.681
DE$131.621
FL$129.10–$141.833
GA$120.59–$135.712
GU$148.941
HI$148.941
IA$121.531
ID$122.311
IL$124.01–$138.424
IN$123.191
KS$120.441
KY$119.581
LA$119.19–$126.412
MA$139.39–$156.982
MD$134.63–$155.683
ME$122.66–$131.312
MI$122.99–$130.622
MN$135.151
MO$116.43–$127.443
MS$115.761
MT$133.261
NC$124.281
ND$131.881
NE$122.451
NH$137.961
NJ$145.06–$153.472
NM$123.651
NV$133.001
NY$126.50–$158.855
OH$122.711
OK$119.741
OR$132.09–$146.322
PA$123.17–$138.872
PR$134.571
RI$137.211
SC$123.681
SD$131.721
TN$121.121
TX$122.16–$140.078
UT$125.741
VA$130.52–$155.682
VI$134.571
VT$130.901
WA$139.28–$160.912
WI$126.551
WV$118.351
WY$132.661

How the 96413 rate is calculated

Each of 96413’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 96413

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.28

0.28 RVUs× 1.000 GPCI

Practice expense3.64

3.64 RVUs× 1.000 GPCI

Malpractice0.07

0.07 RVUs× 1.000 GPCI

Adjusted RVUs

3.9900

Conversion factor

$33.4009

Medicare rate

$133.27

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 96413

The CMS indicators that decide how 96413 is paid alongside other services.

CMS payment indicators · 96413

Chemo IV infusion

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical5Incident-to service.

96413 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • 96413

    Chemo IV infusion0.28 wRVU

    $133.27

  • 96409

    Chemotherapy push0.24 wRVU

    $104.54−$28.73

  • 96365

    IV drug infusion0.21 wRVU

    $67.14−$66.13

  • 96417

    Chemotherapy infusion0.21 wRVU

    $66.47−$66.80

  • 96416

    Pump infusion0.21 wRVU

    $133.27+$0.00

How to choose

96409Chemotherapy push
96409 describes an antineoplastic IV push, including drug administration lasting 15 minutes or less. Use 96413 for a qualifying infusion lasting more than 15 minutes; document its start and stop times.
96365IV drug infusion
96365 is the initial IV infusion of a drug that does not meet chemotherapy administration requirements, such as an antibiotic. Use 96413 for an antineoplastic or other agent that qualifies for high-complexity chemotherapy administration.
96417Chemotherapy infusion
96417 is an add-on for a different chemotherapy drug infused sequentially after the initial drug. Use 96413 for the initial chemotherapy infusion of the encounter.
96416Pump infusion
96416 describes initiation of a prolonged chemotherapy infusion lasting more than eight hours through a portable or implantable pump. Use 96413 for the initial hour of a directly administered IV infusion.

96413 billing questions

How long must the infusion run to report 96413 instead of a push code?

The infusion must last more than 15 minutes. If the drug runs for 15 minutes or less, report 96409 for an antineoplastic IV push.

When is 96415 added for extra time?

Add 96415 for each additional hour of the same infusion once the infusion exceeds 90 minutes. An infusion lasting exactly 90 minutes supports 96413 alone.

Can 96413 be billed more than once on the same day?

Report one initial administration service per encounter unless separate medically necessary IV sites support distinct initial services. Append modifier 59 or, when accepted, XS to the distinct service and document the separate sites.

How are antiemetic premedications and hydration reported with chemotherapy?

A separately administered antiemetic may support 96375 for an IV push or 96367 for a sequential infusion. Medically necessary hydration may support 96361 when its time is separately documented, exceeds 30 minutes, and is not concurrent with the drug infusion.

Is a same-day E/M visit separately billable with 96413?

Yes, when the clinician performs a significant, separately identifiable evaluation beyond the routine pre-infusion assessment; append modifier 25 to the E/M code. Routine nursing checks and vital signs are part of the administration service.

Does 96413 include the chemotherapy drug itself?

No. Report a separately payable drug with its appropriate HCPCS code, often a J code, using units based on the administered dose and documenting any reportable waste.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 96413PPRRVU2026_Oct_nonQPP.csv, line 12,801 (RVU26D)

Open CMS sourceHow we calculate rates

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