Billing code 96521: Pump refillMedicare rate & RVUs

Reports refilling and maintaining a portable infusion pump used to deliver medication over time, when the pump service is performed under physician supervision.

CMS RVU26DEffective Oct 1, 2026109 payment localities58.1K Medicare services in 2024

Medicare pays $143.62 for 96521 nationally in the office. Local office rates run $123.56–$202.66.

Medicare rate · 96521

Pump refill

Swap in your local Medicare rate.

Work RVUs
0.21
Total RVUs
4.30
Global days
XXX

National rate · 2026

$143.62

Office setting, before claim adjustments.

See every locality for 96521 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 96521 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 96521 covers

This service covers refilling and maintaining a portable infusion pump that delivers medication over time. It is commonly performed in an office or outpatient setting during ongoing treatment, including ambulatory infusion regimens. The work centers on the portable pump and its continued operation, rather than an injection or care of an implanted pump.

Report 96521 for the portable-pump refill and maintenance service, and document the device, work performed, and treatment context. Use 96522 when the service involves an implanted pump or reservoir; 96523 describes irrigation of a drug-delivery device. CMS classifies 96521 as an incident-to service: it may be billed only when performed under physician supervision.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 96521 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$123.56 to $202.66

$123.56$163.11$202.66
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

96521 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$125.83Unavailable
Alaska*$154.81Unavailable
Arizona$139.12Unavailable
Arkansas$123.56Unavailable
Atlanta$146.26Unavailable
Austin$151.16Unavailable
Bakersfield$155.73Unavailable
Baltimore/Surr. Cntys$154.09Unavailable
Beaumont$131.37Unavailable
Brazoria$141.96Unavailable

96521 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$123.56

$179.11

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
96521 office rate range by state
State / territoryOffice rate rangeLocalities
AK$154.811
AL$125.831
AR$123.561
AZ$139.121
CA$155.55–$202.6629
CO$151.791
CT$154.591
DC$168.171
DE$141.811
FL$138.89–$152.703
GA$129.57–$146.262
GU$161.031
HI$161.031
IA$130.801
ID$131.651
IL$133.26–$149.104
IN$132.621
KS$129.571
KY$128.521
LA$128.08–$136.022
MA$150.38–$169.702
MD$145.11–$168.173
ME$132.00–$141.552
MI$132.24–$140.532
MN$145.871
MO$125.03–$137.183
MS$124.351
MT$143.621
NC$133.781
ND$142.241
NE$131.831
NH$148.841
NJ$156.48–$165.712
NM$132.951
NV$143.371
NY$136.22–$171.455
OH$131.961
OK$128.741
OR$142.39–$158.042
PA$132.49–$149.712
PR$145.071
RI$147.941
SC$133.071
SD$142.071
TN$130.321
TX$131.37–$151.168
UT$135.331
VA$140.65–$168.172
VI$145.071
VT$141.131
WA$150.27–$174.032
WI$136.371
WV$127.041
WY$143.021

How the 96521 rate is calculated

Each of 96521’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 96521

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.21Practice expense 4.02Malpractice 0.07

4.3000 adjusted RVUs×$33.4009 conversion factor=$143.62

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 96521

The CMS indicators that decide how 96521 is paid alongside other services.

CMS payment indicators · 96521

Pump refill

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical5Incident-to service.

96521 compared with similar codes

Compare codes

96521 vs 96522 vs 96523 vs 96416: national Medicare rates

Swap in your local Medicare rate.

  • 96521
    Pump refill · 0.21 wRVU
    $143.62
  • 96522
    Pump refill · 0.21 wRVU
    $125.25−$18.37
  • 96523
    · 0.04 wRVU
    —
  • 96416
    Pump infusion · 0.21 wRVU
    $133.27−$10.35

How to choose

96522Pump refill
Choose 96521 for a portable pump; choose 96522 when refilling and maintaining an implanted pump or reservoir.
96523Irrig drug delivery device
96523 describes irrigation of a drug-delivery device. It does not describe refilling and maintaining a portable infusion pump.
96416Pump infusion
96416 reports initiation of a prolonged chemotherapy infusion requiring a pump; 96521 reports portable-pump refill and maintenance.

96521 billing questions

How is 96521 different from 96522?

96521 is for refill and maintenance of a portable pump. Use 96522 for an implanted pump or drug-delivery reservoir.

When would 96523 apply instead?

96523 describes irrigation of a drug-delivery device, not refill and maintenance of a portable pump. Select based on the service actually performed.

Can clinical staff perform the service?

CMS classifies 96521 as incident-to and permits billing only when the service is performed under physician supervision.

What documentation supports 96521?

Document that the device is a portable pump, the refill and maintenance work performed, and the treatment context. The record should support that the billed service was performed under physician supervision.

Is 96521 the code for starting a prolonged infusion?

No. 96521 describes portable-pump refill and maintenance. Code 96416 describes initiation of a prolonged chemotherapy infusion requiring a pump, when that service is performed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 96521PPRRVU2026_Oct_nonQPP.csv, line 12,812 (RVU26D)

Open CMS sourceHow we calculate rates

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