HCPCS Q4125: Dermal allograftMedicare rate & RVUs

Q4125 identifies ArthroFlex dermal allograft used to reinforce or reconstruct soft tissue, reported with a primary procedure and measured by area.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4125 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4125

Dermal allograft

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4125 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4125 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4125 covers

Q4125 identifies ArthroFlex, a human acellular dermal matrix used as graft material in soft-tissue repair or reinforcement. Orthopedic surgeons commonly use dermal grafts in procedures such as rotator cuff repair; other reconstructive procedures may use them to reinforce or replace deficient soft tissue. The code represents the product, not the surgeon’s operative work, and is reported by the treating facility or clinician furnishing the material according to the applicable claim setting.

Report the quantity in square centimeters and retain documentation showing the product used and the area applied. CMS classifies Q4125 as an add-on code: report it only with a primary procedure, and its payment falls within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation. The CMS file assigns no physician work RVUs to Q4125, so the code represents the technical side rather than professional interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4125 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4125 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4125 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4125 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4125 rate is calculated

Each of Q4125’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4125

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4125

The CMS indicators that decide how Q4125 is paid alongside other services.

CMS payment indicators · Q4125

Dermal allograft

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4125 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4125

    Dermal allograft0 wRVU

    $127.26

  • Q4128

    Skin matrix0 wRVU

    $127.26+$0.00

  • Q4116

    Dermal matrix0 wRVU

    $127.26+$0.00

  • Q4122

    Wound matrix0 wRVU

    $127.26+$0.00

How to choose

Q4128Skin matrix
Q4128 identifies FlexHD and related products; Q4125 identifies ArthroFlex. Select the code matching the product furnished.
Q4116Dermal matrix
Q4116 is the product-specific code for AlloDerm. It is not the code for ArthroFlex, even when both are used as dermal matrices.
Q4122Wound matrix
Q4122 identifies DermACELL AWM, while Q4125 identifies ArthroFlex. The product record determines which code applies.

Q4125 billing questions

Can Q4125 be billed by itself?

No. CMS identifies Q4125 as an add-on code that must be reported with a primary procedure.

How should the quantity be reported?

Report the ArthroFlex material by square centimeter. Documentation should support the product used and the area applied.

Does Q4125 include the surgeon’s work?

No. The code identifies the graft material. CMS classifies it as technical-component-only, with interpretation covered by a separate code.

How does the global-period rule affect Q4125?

CMS places payment for this add-on within the primary procedure’s global period. Report Q4125 with that primary procedure, not as a standalone service.

Is Q4125 interchangeable with other dermal matrix codes?

No. Q4125 identifies ArthroFlex specifically. Other graft products have their own HCPCS codes and should not be substituted based only on a general similarity in material or use.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4125PPRRVU2026_Oct_nonQPP.csv, line 18,221 (RVU26D)

Open CMS sourceHow we calculate rates

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