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HCPCS Q4151: Amniotic membraneMedicare rate & RVUs

Reports the Amnioband/Guardian amniotic membrane wound product by square centimeter when supplied for graft coverage of a wound.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4151 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4151

Amniotic membrane

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4151 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4151 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4151 covers

Q4151 identifies Amnioband or Guardian, an amniotic membrane-based wound product supplied for coverage of a prepared wound bed. It represents the product rather than the clinician’s application service. Wound-care clinicians, podiatrists, and surgeons may use the material in office wound clinics or hospital outpatient settings as part of wound treatment.

Report the code only with a primary procedure; CMS treats it as an add-on and pays it within that procedure’s global period. Select Q4151 based on the specific product furnished, and report units according to the product’s one-square-centimeter billing unit. Documentation should identify the product, wound site, treated area, amount used, and associated primary procedure. CMS classifies Q4151 as technical-component-only; a separate code represents interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4151 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4151 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4151 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4151 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4151 rate is calculated

Each of Q4151’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4151

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4151

The CMS indicators that decide how Q4151 is paid alongside other services.

CMS payment indicators · Q4151

Amniotic membrane

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4151 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4151

    Amniotic membrane0 wRVU

    $127.26

  • Q4150

    Wound matrix0 wRVU

    $127.26+$0.00

  • Q4152

    Skin substitute0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

How to choose

Q4150Wound matrix
Q4150 identifies Allowrap DS or Dry; Q4151 identifies Amnioband or Guardian. Select the code for the product actually furnished.
Q4152Skin substitute
Q4152 identifies Dermapure, not Amnioband or Guardian. The shared square-centimeter unit does not make the product codes interchangeable.
15271Skin substitute graft
15271 reports the primary application procedure for qualifying trunk, arm, or leg wounds; Q4151 reports the Amnioband/Guardian product supplied with a primary procedure.

Codes related to Q4151

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q4151
CodeHow it relatesNational office range
Primary code
15271Skin substitute graftPrimary skin-substitute application procedure for qualifying trunk, arm, or leg wounds.$140.17–$205.27
15275Skin substitutePrimary skin-substitute application procedure for qualifying wounds at other specified sites.$143.80–$205.40
Used instead
Q4150Wound matrixAllowrap DS or Dry is a different wound-product code billed by square centimeter.$109.31–$183.51
Q4152Skin substituteDermapure is a different wound-product code billed by square centimeter.$109.31–$183.51

Q4151 billing questions

When should Q4151 be selected instead of another skin substitute product code?

Use Q4151 when the product furnished is Amnioband or Guardian. Other wound products have their own HCPCS codes, even when they are also supplied by area.

Can Q4151 be billed by itself?

No. CMS identifies it as an add-on code that must be reported with a primary procedure and paid within that procedure’s global period.

How is the quantity reported?

The code’s billing unit is one square centimeter. Document the treated area and the amount of Amnioband or Guardian used.

Does Q4151 include the wound application service?

No. Q4151 identifies the product; report the applicable primary wound procedure separately for the clinician’s application service.

Does Q4151 include interpretation?

No. CMS classifies Q4151 as technical-component-only and indicates that a separate code covers interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4151PPRRVU2026_Oct_nonQPP.csv, line 18,244 (RVU26D)

Open CMS sourceHow we calculate rates

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