HCPCS Q4159: Wound productMedicare rate & RVUs
Q4159 reports Affinity, a placental tissue wound product, by square centimeter when supplied with a separately reported wound-graft application procedure.
Medicare pays $127.26 for Q4159 nationally in the office. Local office rates run $109.31–$183.51.
Medicare rate · Q4159
Wound product
Swap in your local Medicare rate.
- Work RVUs
- 0
- Total RVUs
- 3.81
- Global days
- ZZZ
National rate · 2026
$127.26
Office setting, before claim adjustments.
See every locality for Q4159 → · Billed by an NP, PA or therapist? →
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 10 sections
What Q4159 covers
Q4159 identifies Affinity, a placental tissue-derived wound product used as a covering in wound care. It may be used in settings such as hospital outpatient departments and wound clinics, with application performed by clinicians treating wounds, including surgeons, podiatrists, and other wound-care practitioners. The product code identifies the material, not the procedure that places it on the wound.
Report Q4159 with the primary skin-substitute application procedure, such as the appropriate code from the 15271–15278 family, selected by wound site and treated area. Units are based on the product’s square-centimeter measure; the record should identify Affinity and support the quantity reported with the wound and application details. CMS designates Q4159 as an add-on code, payable only with a primary procedure and within that procedure’s global period. CMS also classifies it as technical-component-only, with interpretation represented by a separate code.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4159 pays more and less
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
109 payment localities
$109.31 to $183.51
109 of 109 payment localities
| Payment locality | Office | Facility |
|---|---|---|
| Alabama | $111.35 | Unavailable |
| Alaska* | $135.53 | Unavailable |
| Arizona | $123.31 | Unavailable |
| Arkansas | $109.31 | Unavailable |
| Atlanta | $129.29 | Unavailable |
| Austin | $134.64 | Unavailable |
| Bakersfield | $139.47 | Unavailable |
| Baltimore/Surr. Cntys | $136.55 | Unavailable |
| Beaumont | $115.80 | Unavailable |
| Brazoria | $126.11 | Unavailable |
| Chicago | $127.89 | Unavailable |
| Chico | $139.47 | Unavailable |
| Colorado | $135.40 | Unavailable |
| Connecticut | $137.06 | Unavailable |
| Dallas | $126.75 | Unavailable |
| Dc + Md/Va Suburbs | $149.91 | Unavailable |
| Delaware | $125.73 | Unavailable |
| Detroit | $122.80 | Unavailable |
| East St. Louis | $117.08 | Unavailable |
| El Centro | $139.47 | Unavailable |
| Fort Lauderdale | $128.91 | Unavailable |
| Fort Worth | $125.48 | Unavailable |
| Fresno | $139.47 | Unavailable |
| Galveston | $126.37 | Unavailable |
| Hanford-Corcoran | $139.47 | Unavailable |
| Hawaii, Guam | $144.69 | Unavailable |
| Houston | $126.37 | Unavailable |
| Idaho | $117.08 | Unavailable |
| Indiana | $117.97 | Unavailable |
| Iowa | $116.44 | Unavailable |
| Kansas | $115.04 | Unavailable |
| Kentucky | $113.13 | Unavailable |
| Los Angeles-Long Beach-Anaheim (Los Angeles/Orange Cnty) | $150.55 | Unavailable |
| Madera | $139.47 | Unavailable |
| Manhattan | $147.87 | Unavailable |
| Merced | $139.47 | Unavailable |
| Metropolitan Boston | $151.95 | Unavailable |
| Metropolitan Kansas City | $119.49 | Unavailable |
| Metropolitan Philadelphia | $132.47 | Unavailable |
| Metropolitan St. Louis | $121.15 | Unavailable |
| Miami | $132.47 | Unavailable |
| Minnesota | $130.95 | Unavailable |
| Mississippi | $109.57 | Unavailable |
| Modesto | $139.47 | Unavailable |
| Montana** | $127.26 | Unavailable |
| Napa | $167.73 | Unavailable |
| Nebraska | $117.46 | Unavailable |
| Nevada** | $127.38 | Unavailable |
| New Hampshire | $132.47 | Unavailable |
| New Mexico | $116.70 | Unavailable |
| New Orleans | $119.75 | Unavailable |
| North Carolina | $118.73 | Unavailable |
| North Dakota** | $127.26 | Unavailable |
| Northern Nj | $147.62 | Unavailable |
| Nyc Suburbs/Long Island | $151.31 | Unavailable |
| Ohio | $116.19 | Unavailable |
| Oklahoma | $113.64 | Unavailable |
| Oxnard-Thousand Oaks-Ventura | $150.42 | Unavailable |
| Portland | $141.38 | Unavailable |
| Poughkpsie/N Nyc Suburbs | $139.35 | Unavailable |
| Puerto Rico | $128.66 | Unavailable |
| Queens | $150.42 | Unavailable |
| Redding | $139.47 | Unavailable |
| Rest Of California | $139.47 | Unavailable |
| Rest Of Florida | $121.66 | Unavailable |
| Rest Of Georgia | $113.51 | Unavailable |
| Rest Of Illinois | $116.19 | Unavailable |
| Rest Of Louisiana | $112.62 | Unavailable |
| Rest Of Maine | $117.08 | Unavailable |
| Rest Of Maryland | $128.78 | Unavailable |
| Rest Of Massachusetts | $134.00 | Unavailable |
| Rest Of Michigan | $116.19 | Unavailable |
| Rest Of Missouri | $109.70 | Unavailable |
| Rest Of New Jersey | $138.97 | Unavailable |
| Rest Of New York | $120.89 | Unavailable |
| Rest Of Oregon | $126.75 | Unavailable |
| Rest Of Pennsylvania | $116.82 | Unavailable |
| Rest Of Texas | $120.77 | Unavailable |
| Rest Of Washington | $134.00 | Unavailable |
| Rhode Island | $131.46 | Unavailable |
| Riverside-San Bernardino-Ontario | $139.47 | Unavailable |
| Sacramento-Roseville-Folsom | $148.00 | Unavailable |
| Salinas | $147.49 | Unavailable |
| San Diego-Chula Vista-Carlsbad | $152.20 | Unavailable |
| San Francisco-Oakland-Berkeley (Marin Cnty) | $179.43 | Unavailable |
| San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty) | $179.43 | Unavailable |
| San Jose-Sunnyvale-Santa Clara (San Benito Cnty) | $183.51 | Unavailable |
| San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty) | $183.51 | Unavailable |
| San Luis Obispo-Paso Robles | $144.95 | Unavailable |
| Santa Cruz-Watsonville | $154.62 | Unavailable |
| Santa Maria-Santa Barbara | $148.38 | Unavailable |
| Santa Rosa-Petaluma | $156.27 | Unavailable |
| Seattle (King Cnty) | $156.14 | Unavailable |
| South Carolina | $117.59 | Unavailable |
| South Dakota** | $127.26 | Unavailable |
| Southern Maine | $126.11 | Unavailable |
| Stockton | $139.47 | Unavailable |
| Suburban Chicago | $130.69 | Unavailable |
| Tennessee | $115.68 | Unavailable |
| Utah | $119.62 | Unavailable |
| Vallejo | $167.73 | Unavailable |
| Vermont | $125.98 | Unavailable |
| Virgin Islands | $128.66 | Unavailable |
| Virginia | $125.09 | Unavailable |
| Visalia | $139.47 | Unavailable |
| West Virginia | $110.59 | Unavailable |
| Wisconsin | $121.91 | Unavailable |
| Wyoming** | $127.26 | Unavailable |
| Yuba City | $139.47 | Unavailable |
Q4159 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$109.31
$161.49
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $135.53 | 1 |
| AL | $111.35 | 1 |
| AR | $109.31 | 1 |
| AZ | $123.31 | 1 |
| CA | $139.47–$183.51 | 29 |
| CO | $135.40 | 1 |
| CT | $137.06 | 1 |
| DC | $149.91 | 1 |
| DE | $125.73 | 1 |
| FL | $121.66–$132.47 | 3 |
| GA | $113.51–$129.29 | 2 |
| GU | $144.69 | 1 |
| HI | $144.69 | 1 |
| IA | $116.44 | 1 |
| ID | $117.08 | 1 |
| IL | $116.19–$130.69 | 4 |
| IN | $117.97 | 1 |
| KS | $115.04 | 1 |
| KY | $113.13 | 1 |
| LA | $112.62–$119.75 | 2 |
| MA | $134.00–$151.95 | 2 |
| MD | $128.78–$149.91 | 3 |
| ME | $117.08–$126.11 | 2 |
| MI | $116.19–$122.80 | 2 |
| MN | $130.95 | 1 |
| MO | $109.70–$121.15 | 3 |
| MS | $109.57 | 1 |
| MT | $127.26 | 1 |
| NC | $118.73 | 1 |
| ND | $127.26 | 1 |
| NE | $117.46 | 1 |
| NH | $132.47 | 1 |
| NJ | $138.97–$147.62 | 2 |
| NM | $116.70 | 1 |
| NV | $127.38 | 1 |
| NY | $120.89–$151.31 | 5 |
| OH | $116.19 | 1 |
| OK | $113.64 | 1 |
| OR | $126.75–$141.38 | 2 |
| PA | $116.82–$132.47 | 2 |
| PR | $128.66 | 1 |
| RI | $131.46 | 1 |
| SC | $117.59 | 1 |
| SD | $127.26 | 1 |
| TN | $115.68 | 1 |
| TX | $115.80–$134.64 | 8 |
| UT | $119.62 | 1 |
| VA | $125.09–$149.91 | 2 |
| VI | $128.66 | 1 |
| VT | $125.98 | 1 |
| WA | $134.00–$156.14 | 2 |
| WI | $121.91 | 1 |
| WV | $110.59 | 1 |
| WY | $127.26 | 1 |
How the Q4159 rate is calculated
Each of Q4159’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4159
RVUs × geographic indexes × conversion factor
Swap in your local Medicare rate.
Work 0.00Practice expense 3.81Malpractice 0.00
All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4159
The CMS indicators that decide how Q4159 is paid alongside other services.
CMS payment indicators · Q4159
Wound product
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4159 compared with similar codes
Compare codes
Q4159 vs 15271 vs Q4158 vs Q4160: national Medicare rates
Swap in your local Medicare rate.
How to choose
- 15271Skin substitute graft
- 15271 reports the application procedure for qualifying trunk, arm, or leg wounds; Q4159 identifies the Affinity product used with an application procedure.
- Q4158Wound matrix
- Q4158 identifies Kerecis Omega3, not Affinity. Select the product-specific code matching the material supplied.
- Q4160Wound product
- Q4160 identifies NuShield rather than Affinity. The shared square-centimeter measure does not make the product codes interchangeable.
Q4159 billing questions
Does Q4159 report the Affinity product or its application?
It identifies the Affinity wound product. Report the appropriate skin-substitute application procedure separately for placement.
Which application procedure is reported with Q4159?
Choose the applicable code from the 15271–15278 family based on the wound site and treated area. Q4159 must be reported with a primary procedure.
How are Q4159 units determined?
The code is measured per square centimeter. Document the Affinity product and the quantity supporting the units billed.
Can Q4159 be billed by itself?
No. CMS designates it as an add-on code that is billed with a primary procedure and paid within that procedure’s global period.
Does Q4159 include interpretation?
No. CMS classifies Q4159 as technical-component-only; interpretation is represented by a separate code.
Can Q4159 be used for another wound product measured by area?
No. Q4159 identifies Affinity specifically. Use the HCPCS code matching the product actually supplied, even when another product is also measured per square centimeter.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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