HCPCS Q4216: Wound productMedicare rate & RVUs

Reports the square-centimeter quantity of Artacent Cord used in wound treatment, alongside the primary procedure that applies the tissue product.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4216 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4216

Wound product

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4216 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4216 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4216 covers

Q4216 identifies Artacent Cord, a cord-derived tissue product used in wound treatment. A wound-care clinician or surgeon applies the product to a prepared wound as part of a treatment plan; the product code represents the material rather than the clinician’s application work. The service may be furnished in an office or hospital outpatient setting.

Report Q4216 with the primary procedure for applying the product, selected according to the wound’s location and the applicable treatment area. Units represent the square centimeters of product reported. Documentation should identify Artacent Cord, the wound site, the amount used, and the related application procedure. CMS classifies Q4216 as an add-on code, so it is reported only with a primary procedure and paid within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4216 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4216 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4216 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4216 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4216 rate is calculated

Each of Q4216’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4216

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4216

The CMS indicators that decide how Q4216 is paid alongside other services.

CMS payment indicators · Q4216

Wound product

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4216 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4216

    Wound product0 wRVU

    $127.26

  • Q4214

    Wound graft0 wRVU

    $127.26+$0.00

  • Q4218

    Wound graft0 wRVU

    $127.26+$0.00

  • Q4205

    Membrane graft0 wRVU

    $127.26+$0.00

How to choose

Q4214Wound graft
Q4214 identifies Cellesta Cord, while Q4216 identifies Artacent Cord. Select the code for the specific product used; the shared per-square-centimeter measure does not make them interchangeable.
Q4218Wound graft
Q4218 identifies Surgicord. Q4216 is specific to Artacent Cord, so distinguish them by the product documented and applied.
Q4205Membrane graft
Q4205 identifies a membrane graft or wrap product. Q4216 is specific to Artacent Cord; use the code matching the product furnished.

Q4216 billing questions

Which application code should accompany Q4216?

Pair it with the primary skin-substitute application procedure that matches the wound location and treatment area. For example, application codes in the 15271–15278 family cover different locations and area ranges.

How many units should be reported?

Report units based on the square centimeters of Artacent Cord used. Document the product quantity and wound area treated.

Can Q4216 be billed by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure; payment falls within that procedure’s global period.

Does Q4216 include the application work?

No. Q4216 identifies the product. Report the applicable primary procedure for the clinician’s application work.

What documentation supports Q4216?

Record that Artacent Cord was used, the wound site, the square-centimeter quantity, and the related primary application procedure.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4216PPRRVU2026_Oct_nonQPP.csv, line 18,307 (RVU26D)

Open CMS sourceHow we calculate rates

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