HCPCS Q4229: Amniotic membraneMedicare rate & RVUs

Reports Cogenex amniotic membrane furnished for wound coverage, measured by the square centimeter and paired with the applicable skin-substitute application procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4229 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4229

Amniotic membrane

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4229 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4229 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4229 covers

Q4229 identifies Cogenex amniotic membrane supplied for wound coverage, with the product quantity measured in square centimeters. It represents the product rather than the clinician’s wound preparation or application work. It may be used in wound-care settings where a clinician applies the membrane as part of treatment; the application procedure is reported separately. The code is specific to this Cogenex membrane and should not be substituted for another product code based only on the products’ shared amniotic origin.

Report Q4229 with the primary skin-substitute application procedure appropriate to the wound’s site and treated area, using documentation of the product and square centimeters furnished. CMS classifies it as an add-on code, so it is billed only with a primary procedure and paid within that procedure’s global period. Its valuation reflects practice expense, with no physician work or malpractice RVUs. It is technical-component-only; a separate code covers interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4229 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4229 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4229 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4229 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4229 rate is calculated

Each of Q4229’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4229

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4229

The CMS indicators that decide how Q4229 is paid alongside other services.

CMS payment indicators · Q4229

Amniotic membrane

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4229 compared with similar codes

Compare codes

Q4229 vs Q4230 vs 15271 vs 15275: national Medicare rates

Swap in your local Medicare rate.

  • Q4229
    Amniotic membrane · 0 wRVU
    $127.26
  • Q4230
    · 0 wRVU
    —
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73
  • 15275
    Skin substitute · 1.78 wRVU
    $160.32+$33.06

How to choose

Q4230Cogenex flow amnion 0.5 cc
Q4230 identifies Cogenex Flow amnion and is measured per 0.5 cc; Q4229 identifies Cogenex amniotic membrane and is measured per square centimeter. Report the code for the product actually furnished.
15271Skin substitute graft
15271 reports the application procedure for qualifying wounds on the trunk, arms, or legs; Q4229 reports the Cogenex membrane product used with an application procedure.
15275Skin substitute
15275 reports the application procedure for qualifying wounds at specified anatomical sites, including the head, face, neck, hands, feet, or genitalia. Q4229 reports the product, not the application.

Q4229 billing questions

Can Q4229 be billed by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure. Pair it with the applicable skin-substitute application procedure.

How are units reported?

The code is measured per square centimeter. Document the product quantity furnished and the wound site and treated area supporting the reported units.

Is the application work included in Q4229?

No. Q4229 identifies the Cogenex membrane product; report the appropriate application procedure separately. CMS pays Q4229 within that primary procedure’s global period.

How does Q4229 differ from Q4230?

Q4229 identifies Cogenex amniotic membrane measured by square centimeter. Q4230 identifies Cogenex Flow amnion measured by 0.5 cc, so select the code matching the product furnished.

Does Q4229 include interpretation?

No. CMS classifies Q4229 as technical-component-only and assigns interpretation to a separate code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4229PPRRVU2026_Oct_nonQPP.csv, line 18,319 (RVU26D)

Open CMS sourceHow we calculate rates

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