HCPCS Q4264: Wound membraneMedicare rate & RVUs

Reports Cocoon membrane by square centimeter when furnished for wound coverage with a separately coded primary application procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities8.5K Medicare services in 2024

Medicare pays $127.26 for Q4264 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4264

Wound membrane

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4264 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4264 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4264 covers

Q4264 identifies Cocoon membrane supplied for wound coverage, with the quantity measured in square centimeters. It represents the product, not the clinician’s wound preparation or placement service. Wound-care clinicians may use the membrane in outpatient treatment of wounds; the application procedure is coded separately according to wound location and treated area.

CMS classifies Q4264 as an add-on, so report it only with a primary procedure; payment is handled within that procedure’s global period. Base the quantity on the Cocoon membrane furnished and keep documentation linking the product and amount to the treated wound. CMS identifies this as a technical-component-only code, with interpretation covered by a separate code. The CMS work RVU is zero, so the application service must be represented separately when performed.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4264 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4264 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4264 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4264 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4264 rate is calculated

Each of Q4264’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4264

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4264

The CMS indicators that decide how Q4264 is paid alongside other services.

CMS payment indicators · Q4264

Wound membrane

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4264 compared with similar codes

Compare codes

Q4264 vs Q4253 vs Q4263 vs 15271: national Medicare rates

Swap in your local Medicare rate.

  • Q4264
    Wound membrane · 0 wRVU
    $127.26
  • Q4253
    Amniotic membrane · 0 wRVU
    $127.26+$0.00
  • Q4263
    Surgraft TL · 0 wRVU
    $127.26+$0.00
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73

How to choose

Q4253Amniotic membrane
Q4253 identifies Zenith amniotic membrane, while Q4264 identifies Cocoon membrane. Select the code matching the product furnished.
Q4263Surgraft TL
Q4263 identifies Surgraft TL rather than Cocoon membrane. These product-specific supply codes are not interchangeable based only on the wound site.
15271Skin substitute graft
15271 reports the application service for the specified body regions and area range; Q4264 reports the Cocoon membrane product by square centimeter.

Q4264 billing questions

How is Q4264 different from the wound application procedure?

Q4264 reports the Cocoon membrane product by square centimeter. Report the applicable wound application procedure separately for the clinician’s placement service.

Can Q4264 be reported by itself?

No. CMS classifies it as an add-on code that must be reported with a primary procedure.

How should the quantity be determined?

Use the square centimeters of Cocoon membrane furnished for the wound, supported by the product and amount documented for the service.

Does this code include interpretation?

No. CMS identifies Q4264 as technical-component-only; a separate code covers interpretation.

Why does the primary procedure matter for payment?

CMS places payment for Q4264 within the primary procedure’s global period, so it is reported with that procedure rather than as a stand-alone service.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4264PPRRVU2026_Oct_nonQPP.csv, line 18,352 (RVU26D)

Open CMS sourceHow we calculate rates

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