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HCPCS Q4375: Wound graftMedicare rate & RVUs

Reports Duograft AC product used in wound treatment, measured by the number of square centimeters supplied for application with a primary procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4375 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4375

Wound graft

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4375 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4375 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4375 covers

Q4375 identifies Duograft AC, a wound graft product reported by the square centimeter. It represents the product used during wound treatment, not the clinician’s work to prepare or apply it. Wound-care clinicians, surgeons, and podiatrists may use graft products in outpatient wound clinics or procedural settings; the code applies specifically when the product used is Duograft AC.

Report the quantity in square centimeters and pair Q4375 with the applicable primary procedure; it is not billed by itself. Documentation should identify Duograft AC, the treated wound, the amount used, and the associated procedure. CMS classifies this as an add-on code paid within the primary procedure’s global period. It is also a technical-component-only code: interpretation is covered by a separate code, not Q4375.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4375 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4375 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4375 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4375 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4375 rate is calculated

Each of Q4375’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4375

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4375

The CMS indicators that decide how Q4375 is paid alongside other services.

CMS payment indicators · Q4375

Wound graft

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4375 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4375

    Wound graft0 wRVU

    $127.26

  • Q4376

    Not on the physician fee schedule0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

  • Q4377

    Skin substitute0 wRVU

    $127.26+$0.00

How to choose

Q4376Duograft aa per sq cm
Q4376 identifies Duograft AA, while Q4375 identifies Duograft AC. Select the product code matching the graft actually used.
15271Skin substitute graft
billing code 15271 reports a wound-application procedure when its site and area criteria are met; Q4375 reports the Duograft AC product.
Q4377Skin substitute
Q4377 identifies Trigraft FT rather than Duograft AC. The product used determines which supply code to report.

Codes related to Q4375

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q4375
CodeHow it relatesNational office range
Primary code
15271Skin substitute graftPrimary wound-application procedure that may accompany the product, depending on site and procedure criteria.$140.17–$205.27
15275Skin substituteAnother potential primary wound-application procedure, selected according to the treated site and criteria.$143.80–$205.40
Same family
Q4376Duograft aa per sq cmDuograft AA is a distinct named product billed by the square centimeter.$109.31–$183.51

Q4375 billing questions

Can Q4375 be reported without a wound application procedure?

No. CMS identifies Q4375 as an add-on code, so it must be billed with a primary procedure.

How is the quantity determined?

Report the Duograft AC product quantity by the square centimeter. Document the amount used and identify the product.

Which code reports the graft application?

Use the applicable primary wound-application procedure code. For example, billing code 15271 or 15275 may apply depending on wound location and the procedure’s criteria.

Does Q4375 include interpretation?

No. CMS classifies Q4375 as technical-component-only; a separate code covers interpretation.

How does Q4375 relate to the primary procedure’s global period?

CMS states that Q4375 is paid within the primary procedure’s global period and must be reported with that procedure.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4375PPRRVU2026_Oct_nonQPP.csv, line 18,461 (RVU26D)

Open CMS sourceHow we calculate rates

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