HCPCS Q4382: Skin substituteMedicare rate & RVUs

Reports the per-square-centimeter Advograft Dual wound product used with a primary skin-substitute application procedure, with units supported by product and wound records.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4382 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4382

Skin substitute

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4382 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4382 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4382 covers

Advograft Dual is a skin substitute product used to cover a prepared wound bed. Wound-care clinicians, surgeons, and podiatrists may use it in outpatient wound clinics, physician offices, or hospital outpatient settings. This HCPCS line identifies the product rather than the clinician’s work applying it; the application procedure is reported separately with the appropriate procedure code for the wound site and extent.

Report Q4382 for the Advograft Dual product furnished, using the documented square-centimeter quantity. The record should identify the product and support the amount used and the wound treated. CMS classifies this as an add-on code: submit it with a primary procedure, and its payment falls within that procedure’s global period. CMS also classifies it as technical-component-only, with interpretation represented by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4382 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4382 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4382 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4382 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4382 rate is calculated

Each of Q4382’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4382

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4382

The CMS indicators that decide how Q4382 is paid alongside other services.

CMS payment indicators · Q4382

Skin substitute

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4382 compared with similar codes

Compare codes

Q4382 vs Q4380 vs 15271 vs 15275: national Medicare rates

Swap in your local Medicare rate.

  • Q4382
    Skin substitute · 0 wRVU
    $127.26
  • Q4380
    Wound graft · 0 wRVU
    $127.26+$0.00
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73
  • 15275
    Skin substitute · 1.78 wRVU
    $160.32+$33.06

How to choose

Q4380Wound graft
Q4380 identifies Advograft One, while Q4382 identifies Advograft Dual. Use the product code matching the material furnished.
15271Skin substitute graft
Q4382 reports the Advograft Dual product; 15271 reports application work for qualifying trunk, arm, or leg wounds.
15275Skin substitute
Q4382 reports the product; 15275 reports application work for qualifying wounds on the head, face, neck, hands, feet, or genitalia.

Q4382 billing questions

How is Q4382 different from Q4380?

Q4382 identifies Advograft Dual; Q4380 identifies Advograft One. Choose the code matching the product furnished, not the wound size.

Does Q4382 include the application?

No. It identifies the product. Report the applicable skin-substitute application procedure separately for the wound site and extent.

Can Q4382 be reported by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure; payment is within that procedure’s global period.

What supports the number of units?

The code is measured per square centimeter. Document the product used and the square-centimeter quantity associated with the treated wound.

How is interpretation represented?

CMS classifies Q4382 as technical-component-only. A separate code represents interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4382PPRRVU2026_Oct_nonQPP.csv, line 18,467 (RVU26D)

Open CMS sourceHow we calculate rates

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