HCPCS Q4392: Skin substituteMedicare rate & RVUs
Reports Grafix Duo by square centimeter when the product is used as a wound covering with a qualifying skin-substitute application procedure.
Medicare pays $127.26 for Q4392 nationally in the office. Local office rates run $109.31–$183.51.
Medicare rate · Q4392
Skin substitute
- Work RVUs
- 0
- Total RVUs
- 3.81
- Global days
- ZZZ
National rate · 2026
$127.26
Office setting, before claim adjustments.
See every locality for Q4392 →Billed by an NP, PA or therapist? →
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 10 sections
What Q4392 covers
Q4392 identifies Grafix Duo, a wound-care skin substitute product measured by the square centimeter. It is used when clinicians apply the product to a wound as part of wound management. Wound-care physicians, podiatrists, and surgeons may use skin substitutes in outpatient wound clinics or other settings where wounds are treated; the code identifies the product, not the clinician’s application work.
Report units according to the documented square centimeters of Grafix Duo used, and identify the product and treated wound in the record. Pair Q4392 with the primary skin-substitute application procedure appropriate to the wound site and treatment extent. CMS classifies Q4392 as an add-on code: it is billed only with a primary procedure, and payment falls within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4392 pays more and less
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
109 payment localities
$109.31 to $183.51
109 of 109 payment localities
| Payment locality | Office | Facility |
|---|---|---|
| Alabama | $111.35 | Unavailable |
| Alaska* | $135.53 | Unavailable |
| Arizona | $123.31 | Unavailable |
| Arkansas | $109.31 | Unavailable |
| Atlanta | $129.29 | Unavailable |
| Austin | $134.64 | Unavailable |
| Bakersfield | $139.47 | Unavailable |
| Baltimore/Surr. Cntys | $136.55 | Unavailable |
| Beaumont | $115.80 | Unavailable |
| Brazoria | $126.11 | Unavailable |
| Chicago | $127.89 | Unavailable |
| Chico | $139.47 | Unavailable |
| Colorado | $135.40 | Unavailable |
| Connecticut | $137.06 | Unavailable |
| Dallas | $126.75 | Unavailable |
| Dc + Md/Va Suburbs | $149.91 | Unavailable |
| Delaware | $125.73 | Unavailable |
| Detroit | $122.80 | Unavailable |
| East St. Louis | $117.08 | Unavailable |
| El Centro | $139.47 | Unavailable |
| Fort Lauderdale | $128.91 | Unavailable |
| Fort Worth | $125.48 | Unavailable |
| Fresno | $139.47 | Unavailable |
| Galveston | $126.37 | Unavailable |
| Hanford-Corcoran | $139.47 | Unavailable |
| Hawaii, Guam | $144.69 | Unavailable |
| Houston | $126.37 | Unavailable |
| Idaho | $117.08 | Unavailable |
| Indiana | $117.97 | Unavailable |
| Iowa | $116.44 | Unavailable |
| Kansas | $115.04 | Unavailable |
| Kentucky | $113.13 | Unavailable |
| Los Angeles-Long Beach-Anaheim (Los Angeles/Orange Cnty) | $150.55 | Unavailable |
| Madera | $139.47 | Unavailable |
| Manhattan | $147.87 | Unavailable |
| Merced | $139.47 | Unavailable |
| Metropolitan Boston | $151.95 | Unavailable |
| Metropolitan Kansas City | $119.49 | Unavailable |
| Metropolitan Philadelphia | $132.47 | Unavailable |
| Metropolitan St. Louis | $121.15 | Unavailable |
| Miami | $132.47 | Unavailable |
| Minnesota | $130.95 | Unavailable |
| Mississippi | $109.57 | Unavailable |
| Modesto | $139.47 | Unavailable |
| Montana** | $127.26 | Unavailable |
| Napa | $167.73 | Unavailable |
| Nebraska | $117.46 | Unavailable |
| Nevada** | $127.38 | Unavailable |
| New Hampshire | $132.47 | Unavailable |
| New Mexico | $116.70 | Unavailable |
| New Orleans | $119.75 | Unavailable |
| North Carolina | $118.73 | Unavailable |
| North Dakota** | $127.26 | Unavailable |
| Northern Nj | $147.62 | Unavailable |
| Nyc Suburbs/Long Island | $151.31 | Unavailable |
| Ohio | $116.19 | Unavailable |
| Oklahoma | $113.64 | Unavailable |
| Oxnard-Thousand Oaks-Ventura | $150.42 | Unavailable |
| Portland | $141.38 | Unavailable |
| Poughkpsie/N Nyc Suburbs | $139.35 | Unavailable |
| Puerto Rico | $128.66 | Unavailable |
| Queens | $150.42 | Unavailable |
| Redding | $139.47 | Unavailable |
| Rest Of California | $139.47 | Unavailable |
| Rest Of Florida | $121.66 | Unavailable |
| Rest Of Georgia | $113.51 | Unavailable |
| Rest Of Illinois | $116.19 | Unavailable |
| Rest Of Louisiana | $112.62 | Unavailable |
| Rest Of Maine | $117.08 | Unavailable |
| Rest Of Maryland | $128.78 | Unavailable |
| Rest Of Massachusetts | $134.00 | Unavailable |
| Rest Of Michigan | $116.19 | Unavailable |
| Rest Of Missouri | $109.70 | Unavailable |
| Rest Of New Jersey | $138.97 | Unavailable |
| Rest Of New York | $120.89 | Unavailable |
| Rest Of Oregon | $126.75 | Unavailable |
| Rest Of Pennsylvania | $116.82 | Unavailable |
| Rest Of Texas | $120.77 | Unavailable |
| Rest Of Washington | $134.00 | Unavailable |
| Rhode Island | $131.46 | Unavailable |
| Riverside-San Bernardino-Ontario | $139.47 | Unavailable |
| Sacramento-Roseville-Folsom | $148.00 | Unavailable |
| Salinas | $147.49 | Unavailable |
| San Diego-Chula Vista-Carlsbad | $152.20 | Unavailable |
| San Francisco-Oakland-Berkeley (Marin Cnty) | $179.43 | Unavailable |
| San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty) | $179.43 | Unavailable |
| San Jose-Sunnyvale-Santa Clara (San Benito Cnty) | $183.51 | Unavailable |
| San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty) | $183.51 | Unavailable |
| San Luis Obispo-Paso Robles | $144.95 | Unavailable |
| Santa Cruz-Watsonville | $154.62 | Unavailable |
| Santa Maria-Santa Barbara | $148.38 | Unavailable |
| Santa Rosa-Petaluma | $156.27 | Unavailable |
| Seattle (King Cnty) | $156.14 | Unavailable |
| South Carolina | $117.59 | Unavailable |
| South Dakota** | $127.26 | Unavailable |
| Southern Maine | $126.11 | Unavailable |
| Stockton | $139.47 | Unavailable |
| Suburban Chicago | $130.69 | Unavailable |
| Tennessee | $115.68 | Unavailable |
| Utah | $119.62 | Unavailable |
| Vallejo | $167.73 | Unavailable |
| Vermont | $125.98 | Unavailable |
| Virgin Islands | $128.66 | Unavailable |
| Virginia | $125.09 | Unavailable |
| Visalia | $139.47 | Unavailable |
| West Virginia | $110.59 | Unavailable |
| Wisconsin | $121.91 | Unavailable |
| Wyoming** | $127.26 | Unavailable |
| Yuba City | $139.47 | Unavailable |
Q4392 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$109.31
$161.49
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $135.53 | 1 |
| AL | $111.35 | 1 |
| AR | $109.31 | 1 |
| AZ | $123.31 | 1 |
| CA | $139.47–$183.51 | 29 |
| CO | $135.40 | 1 |
| CT | $137.06 | 1 |
| DC | $149.91 | 1 |
| DE | $125.73 | 1 |
| FL | $121.66–$132.47 | 3 |
| GA | $113.51–$129.29 | 2 |
| GU | $144.69 | 1 |
| HI | $144.69 | 1 |
| IA | $116.44 | 1 |
| ID | $117.08 | 1 |
| IL | $116.19–$130.69 | 4 |
| IN | $117.97 | 1 |
| KS | $115.04 | 1 |
| KY | $113.13 | 1 |
| LA | $112.62–$119.75 | 2 |
| MA | $134.00–$151.95 | 2 |
| MD | $128.78–$149.91 | 3 |
| ME | $117.08–$126.11 | 2 |
| MI | $116.19–$122.80 | 2 |
| MN | $130.95 | 1 |
| MO | $109.70–$121.15 | 3 |
| MS | $109.57 | 1 |
| MT | $127.26 | 1 |
| NC | $118.73 | 1 |
| ND | $127.26 | 1 |
| NE | $117.46 | 1 |
| NH | $132.47 | 1 |
| NJ | $138.97–$147.62 | 2 |
| NM | $116.70 | 1 |
| NV | $127.38 | 1 |
| NY | $120.89–$151.31 | 5 |
| OH | $116.19 | 1 |
| OK | $113.64 | 1 |
| OR | $126.75–$141.38 | 2 |
| PA | $116.82–$132.47 | 2 |
| PR | $128.66 | 1 |
| RI | $131.46 | 1 |
| SC | $117.59 | 1 |
| SD | $127.26 | 1 |
| TN | $115.68 | 1 |
| TX | $115.80–$134.64 | 8 |
| UT | $119.62 | 1 |
| VA | $125.09–$149.91 | 2 |
| VI | $128.66 | 1 |
| VT | $125.98 | 1 |
| WA | $134.00–$156.14 | 2 |
| WI | $121.91 | 1 |
| WV | $110.59 | 1 |
| WY | $127.26 | 1 |
How the Q4392 rate is calculated
Each of Q4392’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4392
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4392
The CMS indicators that decide how Q4392 is paid alongside other services.
CMS payment indicators · Q4392
Skin substitute
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4392 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 15271Skin substitute graft
- 15271 reports the primary skin-substitute application work; Q4392 identifies the Grafix Duo product by square centimeter and is reported with a primary procedure.
- Q4391Wound product
- Q4391 identifies Amnioplast Double. Choose between the product codes based on the product actually used, not the wound’s appearance.
- Q4393Wound graft
- Q4393 identifies Surgraft AC, while Q4392 identifies Grafix Duo. The product documentation determines which code applies.
Q4392 billing questions
Should Q4392 be reported instead of the skin-substitute application procedure?
No. Q4392 identifies the Grafix Duo product by square centimeter; report the applicable primary procedure for the clinician’s application work.
Can Q4392 be billed by itself?
No. CMS identifies it as an add-on code that must be billed with a primary procedure.
How should the units be determined?
Use the documented square centimeters of Grafix Duo used. The record should identify the product and the wound treated.
What does the global-period rule mean for billing?
Q4392 is paid within the primary procedure’s global period, so it must be reported with that procedure rather than as a stand-alone service.
Does Q4392 include interpretation?
No. CMS classifies Q4392 as technical-component-only and identifies a separate code for interpretation.
Can Q4392 be used for another skin substitute product?
No. Use Q4392 only when the product used is Grafix Duo; select a different product code when another product was applied.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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