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HCPCS code Q4413: Skin substitute2026 Medicare rate & RVUs

Reports each square centimeter of Cygnus Solo supplied for wound coverage with the applicable skin-substitute application procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4413 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4413

Skin substitute

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4413 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4413 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4413 covers

Q4413 represents the Cygnus Solo placental tissue product used to cover a wound as part of skin-substitute treatment. Wound care clinicians and surgeons may apply it in outpatient wound clinics or other settings where wound procedures are performed. The product line is reported separately from the service that prepares and applies the graft; it is not a code for the wound assessment or the application work.

Report the quantity in square centimeters and document the product used, wound location and treated area, and amount applied. Pair Q4413 with the primary application procedure selected for the treated site and wound area. CMS classifies it as an add-on code, paid within that primary procedure’s global period. It is technical-component-only; a separate code covers interpretation. The application procedure and product supply should be supported by the operative or wound-care record.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4413 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4413 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4413 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4413 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4413 rate is calculated

Each of Q4413’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4413

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4413

The CMS indicators that decide how Q4413 is paid alongside other services.

CMS payment indicators · Q4413

Skin substitute

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4413 compared with similar codes

Compare codes · National

5 codes, side by side

  • Q4413

    Skin substitute0 wRVU

    $127.26

  • Q4412

    Wound product0 wRVU

    $127.26+$0.00

  • Q4414

    Wound matrix0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

  • 15275

    Skin substitute1.78 wRVU

    $160.32+$33.06

How to choose

Q4412Wound product
Q4412 identifies Choriofix, not Cygnus Solo. Choose the code that matches the product documented as used.
Q4414Wound matrix
Q4414 identifies Simplichor. It is not interchangeable with Q4413 based on wound size or treatment site.
15271Skin substitute graft
15271 reports the application service for qualifying trunk, arm, or leg wounds; Q4413 reports the Cygnus Solo product supplied per square centimeter.
15275Skin substitute
15275 reports the application service for qualifying wounds at other specified sites; Q4413 reports the Cygnus Solo product rather than application work.

Codes related to Q4413

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q4413
CodeHow it relatesNational office range
Primary code
15271Skin substitute graftPrimary skin-substitute application procedure for qualifying trunk, arm, or leg wounds.$140.17–$205.27
15275Skin substitutePrimary skin-substitute application procedure for qualifying wounds at other specified sites.$143.80–$205.40
Used instead
Q4412Wound productChoriofix is a distinct per-square-centimeter skin-substitute product code.$109.31–$183.51
Q4414Wound matrixSimplichor is a distinct per-square-centimeter skin-substitute product code.$109.31–$183.51

Q4413 billing questions

What determines whether Q4413 is the right product code?

The product used must be Cygnus Solo. Do not select it based only on wound location or size; other skin-substitute products have their own HCPCS codes.

What should be reported with Q4413?

Report it with the primary skin-substitute application procedure appropriate to the wound site and area. Q4413 is an add-on code and is paid within that procedure’s global period.

How are units counted?

The code is reported per square centimeter. Document the wound area treated and the quantity of Cygnus Solo applied.

Does Q4413 include interpretation?

No. CMS classifies Q4413 as technical-component-only and identifies a separate code for interpretation.

What documentation supports the claim?

Record the product as Cygnus Solo, the wound location and treated area, the amount applied, and the associated application procedure.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4413PPRRVU2026_Oct_nonQPP.csv, line 18,498 (RVU26D)

Open CMS sourceHow we calculate rates

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