Billing code 45349: Endoscopic mucosal resectionMedicare rate & RVUs in Alaska

Reports endoscopic mucosal resection of a lesion reached by flexible sigmoidoscopy, typically when a colorectal lesion is lifted and removed endoscopically.

CMS RVU26DEffective Oct 1, 20261 payment locality780 Medicare services in 2024

CMS doesn’t publish an office rate for 45349 in Alaska.

—Office (non-facility)
$229.89Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 45349 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Alaska
  2. What 45349 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What 45349 covers

A gastroenterologist or colorectal surgeon uses a flexible sigmoidoscope to reach a lesion in the rectum or sigmoid colon and perform endoscopic mucosal resection (EMR). The technique commonly involves lifting the lesion from the underlying wall, often with a submucosal injection, then removing the targeted mucosa with an endoscopic resection instrument. It is performed in an endoscopy setting for lesions selected for endoscopic rather than surgical removal.

Report this code when the documented therapeutic service is EMR during flexible sigmoidoscopy, not merely inspection, biopsy, or routine snare removal. The report should identify the lesion’s location and describe the EMR technique and resection performed. Medicare assigns a 0-day global period, so same-day preoperative and postoperative care is included. When related endoscopies are performed together, endoscopy family pricing applies. Modifier 50 is inappropriate; CMS also does not pay an assistant at surgery, and does not permit co-surgeons or team surgery for this service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

45349 in Alaska*

45349 office and facility rates by payment locality
Payment localityOfficeFacility
Alaska*Unavailable$229.89

How the 45349 rate is calculated

Each of 45349’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 45349

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 3.43Practice expense 1.43Malpractice 0.39

5.2500 adjusted RVUs×$33.4009 conversion factor=$175.35

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 45349

The CMS indicators that decide how 45349 is paid alongside other services.

CMS payment indicators · 45349

Endoscopic mucosal resection

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

45349 without 51 · national facility

$175.35

Endoscopic mucosal resection

45349-51 · Second procedure: 50%

$87.68

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

45349 compared with similar codes

Compare codes

45349 vs 45333 vs 45390 vs 45331: national Medicare rates

Swap in your local Medicare rate.

  • 45349
    Endoscopic mucosal resection · 3.43 wRVU
    —
  • 45333
    Flexible sigmoidoscopy · 1.51 wRVU
    $368.08
  • 45390
    Colonoscopy · 5.89 wRVU
    —
  • 45331
    Sigmoidoscopy · 1.11 wRVU
    $322.99

How to choose

45333Flexible sigmoidoscopy
45333 describes lesion removal by snare technique. Choose 45349 when the documented intervention is EMR.
45390Colonoscopy
Both describe EMR, but 45349 is for flexible sigmoidoscopy and 45390 is for colonoscopy.
45331Sigmoidoscopy
45331 is for sigmoidoscopy with biopsy. It does not describe resection of the lesion by EMR.

45349 billing questions

How does this differ from 45333?

Use 45349 for EMR performed through flexible sigmoidoscopy. Code 45333 describes a different lesion-removal technique, snare removal, rather than EMR.

Can diagnostic sigmoidoscopy be reported separately with the EMR?

The inspection that leads to EMR is part of the therapeutic endoscopy. When related endoscopies are performed together, Medicare applies endoscopy family pricing.

What documentation supports reporting 45349?

Document the lesion’s location and the EMR technique and resection performed. The record should distinguish EMR from biopsy, diagnostic examination, or another removal method.

Should modifier 50 be appended for lesions on both sides?

No. CMS identifies bilateral adjustment as inappropriate for this code.

Can an assistant surgeon or co-surgeon be billed?

CMS does not pay an assistant at surgery for this service and does not permit co-surgeons or team surgery.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 45349PPRRVU2026_Oct_nonQPP.csv, line 5,511 (RVU26D)
Geographic factors for Alaska*GPCI2026.csv, line 5 (RVU26D)

Open CMS sourceHow we calculate rates

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