HCPCS Q4327: Amniotic allograftMedicare rate & RVUs in Florida

Reports Duoamnion amniotic membrane allograft supplied for wound application, with units representing the square centimeters furnished alongside a primary procedure.

CMS RVU26DEffective Oct 1, 20263 payment localities

Medicare pays $121.66–$132.47 for Q4327 in the office in Florida, from Rest Of Florida to Miami. Which amount applies depends on the service address.

$121.66–$132.47Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4327 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Florida
  2. What Q4327 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4327 covers

Q4327 identifies Duoamnion, a named amniotic membrane allograft supplied for application to a wound. Wound-care clinicians, including physicians and podiatrists, may use it as a covering on a prepared wound bed during outpatient wound treatment. The product line is distinct from the procedure used to prepare and apply the graft; wound debridement or other wound management may occur in the same encounter when separately supported.

Report Q4327 only with a primary procedure, commonly an appropriate skin-substitute application code from the 15271–15278 family, selected for the treated site and wound area. The product record and clinical documentation should identify Duoamnion, the wound treated, and the square centimeters furnished. CMS classifies Q4327 as an add-on code paid within the primary procedure’s global period, so it is not a stand-alone service. CMS also classifies it as technical-component-only; interpretation is represented by a separate code.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4327 pays more and less in Florida

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

3 payment localities

$121.66 to $132.47

$121.66$127.06$132.47
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.
Q4327 office and facility rates by payment locality
Payment localityOfficeFacility
Fort Lauderdale$128.91Unavailable
Miami$132.47Unavailable
Rest Of Florida$121.66Unavailable

How the Q4327 rate is calculated

Each of Q4327’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4327

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4327

The CMS indicators that decide how Q4327 is paid alongside other services.

CMS payment indicators · Q4327

Amniotic allograft

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4327 compared with similar codes

Compare codes

Q4327 vs Q4328 vs Q4329 vs 15271: national Medicare rates

Swap in your local Medicare rate.

  • Q4327
    Amniotic allograft · 0 wRVU
    $127.26
  • Q4328
    Wound product · 0 wRVU
    $127.26+$0.00
  • Q4329
    Wound graft · 0 wRVU
    $127.26+$0.00
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73

How to choose

Q4328Wound product
Q4328 identifies Most, while Q4327 identifies Duoamnion. The product documentation determines which code to report.
Q4329Wound graft
Q4329 identifies Singlay, not Duoamnion. Do not select between them based only on the shared per-square-centimeter unit.
15271Skin substitute graft
15271 reports a primary skin-substitute application procedure; Q4327 reports the Duoamnion product as an add-on. The appropriate application code depends on the wound site and area.

Q4327 billing questions

What distinguishes Q4327 from another per-square-centimeter graft code?

Q4327 identifies Duoamnion specifically. Select the code that matches the product record rather than choosing among graft codes by unit of measure alone.

Can Q4327 be billed by itself?

No. CMS identifies it as an add-on code that must be reported with a primary procedure; an appropriate skin-substitute application procedure is a common pairing.

How should units be determined?

The code is measured per square centimeter. The product and wound documentation should support the square centimeters reported.

Does Q4327 include interpretation?

No. CMS classifies Q4327 as technical-component-only and indicates that a separate code covers interpretation.

What documentation supports reporting Q4327?

Document the Duoamnion product used, the wound treated, the application procedure, and the square centimeters furnished.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4327PPRRVU2026_Oct_nonQPP.csv, line 18,414 (RVU26D)

Open CMS sourceHow we calculate rates

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