HCPCS Q4327: Amniotic allograftMedicare rate & RVUs
Reports Duoamnion amniotic membrane allograft supplied for wound application, with units representing the square centimeters furnished alongside a primary procedure.
Medicare pays $127.26 for Q4327 nationally in the office. Local office rates run $109.31–$183.51.
Medicare rate · Q4327
Amniotic allograft
Swap in your local Medicare rate.
- Work RVUs
- 0
- Total RVUs
- 3.81
- Global days
- ZZZ
National rate · 2026
$127.26
Office setting, before claim adjustments.
See every locality for Q4327 → · Billed by an NP, PA or therapist? →
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 10 sections
What Q4327 covers
Q4327 identifies Duoamnion, a named amniotic membrane allograft supplied for application to a wound. Wound-care clinicians, including physicians and podiatrists, may use it as a covering on a prepared wound bed during outpatient wound treatment. The product line is distinct from the procedure used to prepare and apply the graft; wound debridement or other wound management may occur in the same encounter when separately supported.
Report Q4327 only with a primary procedure, commonly an appropriate skin-substitute application code from the 15271–15278 family, selected for the treated site and wound area. The product record and clinical documentation should identify Duoamnion, the wound treated, and the square centimeters furnished. CMS classifies Q4327 as an add-on code paid within the primary procedure’s global period, so it is not a stand-alone service. CMS also classifies it as technical-component-only; interpretation is represented by a separate code.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where Q4327 pays more and less
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
109 payment localities
$109.31 to $183.51
109 of 109 payment localities
| Payment locality | Office | Facility |
|---|---|---|
| Alabama | $111.35 | Unavailable |
| Alaska* | $135.53 | Unavailable |
| Arizona | $123.31 | Unavailable |
| Arkansas | $109.31 | Unavailable |
| Atlanta | $129.29 | Unavailable |
| Austin | $134.64 | Unavailable |
| Bakersfield | $139.47 | Unavailable |
| Baltimore/Surr. Cntys | $136.55 | Unavailable |
| Beaumont | $115.80 | Unavailable |
| Brazoria | $126.11 | Unavailable |
| Chicago | $127.89 | Unavailable |
| Chico | $139.47 | Unavailable |
| Colorado | $135.40 | Unavailable |
| Connecticut | $137.06 | Unavailable |
| Dallas | $126.75 | Unavailable |
| Dc + Md/Va Suburbs | $149.91 | Unavailable |
| Delaware | $125.73 | Unavailable |
| Detroit | $122.80 | Unavailable |
| East St. Louis | $117.08 | Unavailable |
| El Centro | $139.47 | Unavailable |
| Fort Lauderdale | $128.91 | Unavailable |
| Fort Worth | $125.48 | Unavailable |
| Fresno | $139.47 | Unavailable |
| Galveston | $126.37 | Unavailable |
| Hanford-Corcoran | $139.47 | Unavailable |
| Hawaii, Guam | $144.69 | Unavailable |
| Houston | $126.37 | Unavailable |
| Idaho | $117.08 | Unavailable |
| Indiana | $117.97 | Unavailable |
| Iowa | $116.44 | Unavailable |
| Kansas | $115.04 | Unavailable |
| Kentucky | $113.13 | Unavailable |
| Los Angeles-Long Beach-Anaheim (Los Angeles/Orange Cnty) | $150.55 | Unavailable |
| Madera | $139.47 | Unavailable |
| Manhattan | $147.87 | Unavailable |
| Merced | $139.47 | Unavailable |
| Metropolitan Boston | $151.95 | Unavailable |
| Metropolitan Kansas City | $119.49 | Unavailable |
| Metropolitan Philadelphia | $132.47 | Unavailable |
| Metropolitan St. Louis | $121.15 | Unavailable |
| Miami | $132.47 | Unavailable |
| Minnesota | $130.95 | Unavailable |
| Mississippi | $109.57 | Unavailable |
| Modesto | $139.47 | Unavailable |
| Montana** | $127.26 | Unavailable |
| Napa | $167.73 | Unavailable |
| Nebraska | $117.46 | Unavailable |
| Nevada** | $127.38 | Unavailable |
| New Hampshire | $132.47 | Unavailable |
| New Mexico | $116.70 | Unavailable |
| New Orleans | $119.75 | Unavailable |
| North Carolina | $118.73 | Unavailable |
| North Dakota** | $127.26 | Unavailable |
| Northern Nj | $147.62 | Unavailable |
| Nyc Suburbs/Long Island | $151.31 | Unavailable |
| Ohio | $116.19 | Unavailable |
| Oklahoma | $113.64 | Unavailable |
| Oxnard-Thousand Oaks-Ventura | $150.42 | Unavailable |
| Portland | $141.38 | Unavailable |
| Poughkpsie/N Nyc Suburbs | $139.35 | Unavailable |
| Puerto Rico | $128.66 | Unavailable |
| Queens | $150.42 | Unavailable |
| Redding | $139.47 | Unavailable |
| Rest Of California | $139.47 | Unavailable |
| Rest Of Florida | $121.66 | Unavailable |
| Rest Of Georgia | $113.51 | Unavailable |
| Rest Of Illinois | $116.19 | Unavailable |
| Rest Of Louisiana | $112.62 | Unavailable |
| Rest Of Maine | $117.08 | Unavailable |
| Rest Of Maryland | $128.78 | Unavailable |
| Rest Of Massachusetts | $134.00 | Unavailable |
| Rest Of Michigan | $116.19 | Unavailable |
| Rest Of Missouri | $109.70 | Unavailable |
| Rest Of New Jersey | $138.97 | Unavailable |
| Rest Of New York | $120.89 | Unavailable |
| Rest Of Oregon | $126.75 | Unavailable |
| Rest Of Pennsylvania | $116.82 | Unavailable |
| Rest Of Texas | $120.77 | Unavailable |
| Rest Of Washington | $134.00 | Unavailable |
| Rhode Island | $131.46 | Unavailable |
| Riverside-San Bernardino-Ontario | $139.47 | Unavailable |
| Sacramento-Roseville-Folsom | $148.00 | Unavailable |
| Salinas | $147.49 | Unavailable |
| San Diego-Chula Vista-Carlsbad | $152.20 | Unavailable |
| San Francisco-Oakland-Berkeley (Marin Cnty) | $179.43 | Unavailable |
| San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty) | $179.43 | Unavailable |
| San Jose-Sunnyvale-Santa Clara (San Benito Cnty) | $183.51 | Unavailable |
| San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty) | $183.51 | Unavailable |
| San Luis Obispo-Paso Robles | $144.95 | Unavailable |
| Santa Cruz-Watsonville | $154.62 | Unavailable |
| Santa Maria-Santa Barbara | $148.38 | Unavailable |
| Santa Rosa-Petaluma | $156.27 | Unavailable |
| Seattle (King Cnty) | $156.14 | Unavailable |
| South Carolina | $117.59 | Unavailable |
| South Dakota** | $127.26 | Unavailable |
| Southern Maine | $126.11 | Unavailable |
| Stockton | $139.47 | Unavailable |
| Suburban Chicago | $130.69 | Unavailable |
| Tennessee | $115.68 | Unavailable |
| Utah | $119.62 | Unavailable |
| Vallejo | $167.73 | Unavailable |
| Vermont | $125.98 | Unavailable |
| Virgin Islands | $128.66 | Unavailable |
| Virginia | $125.09 | Unavailable |
| Visalia | $139.47 | Unavailable |
| West Virginia | $110.59 | Unavailable |
| Wisconsin | $121.91 | Unavailable |
| Wyoming** | $127.26 | Unavailable |
| Yuba City | $139.47 | Unavailable |
Q4327 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$109.31
$161.49
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $135.53 | 1 |
| AL | $111.35 | 1 |
| AR | $109.31 | 1 |
| AZ | $123.31 | 1 |
| CA | $139.47–$183.51 | 29 |
| CO | $135.40 | 1 |
| CT | $137.06 | 1 |
| DC | $149.91 | 1 |
| DE | $125.73 | 1 |
| FL | $121.66–$132.47 | 3 |
| GA | $113.51–$129.29 | 2 |
| GU | $144.69 | 1 |
| HI | $144.69 | 1 |
| IA | $116.44 | 1 |
| ID | $117.08 | 1 |
| IL | $116.19–$130.69 | 4 |
| IN | $117.97 | 1 |
| KS | $115.04 | 1 |
| KY | $113.13 | 1 |
| LA | $112.62–$119.75 | 2 |
| MA | $134.00–$151.95 | 2 |
| MD | $128.78–$149.91 | 3 |
| ME | $117.08–$126.11 | 2 |
| MI | $116.19–$122.80 | 2 |
| MN | $130.95 | 1 |
| MO | $109.70–$121.15 | 3 |
| MS | $109.57 | 1 |
| MT | $127.26 | 1 |
| NC | $118.73 | 1 |
| ND | $127.26 | 1 |
| NE | $117.46 | 1 |
| NH | $132.47 | 1 |
| NJ | $138.97–$147.62 | 2 |
| NM | $116.70 | 1 |
| NV | $127.38 | 1 |
| NY | $120.89–$151.31 | 5 |
| OH | $116.19 | 1 |
| OK | $113.64 | 1 |
| OR | $126.75–$141.38 | 2 |
| PA | $116.82–$132.47 | 2 |
| PR | $128.66 | 1 |
| RI | $131.46 | 1 |
| SC | $117.59 | 1 |
| SD | $127.26 | 1 |
| TN | $115.68 | 1 |
| TX | $115.80–$134.64 | 8 |
| UT | $119.62 | 1 |
| VA | $125.09–$149.91 | 2 |
| VI | $128.66 | 1 |
| VT | $125.98 | 1 |
| WA | $134.00–$156.14 | 2 |
| WI | $121.91 | 1 |
| WV | $110.59 | 1 |
| WY | $127.26 | 1 |
How the Q4327 rate is calculated
Each of Q4327’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4327
RVUs × geographic indexes × conversion factor
Swap in your local Medicare rate.
Work 0.00Practice expense 3.81Malpractice 0.00
All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4327
The CMS indicators that decide how Q4327 is paid alongside other services.
CMS payment indicators · Q4327
Amniotic allograft
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4327 compared with similar codes
Compare codes
Q4327 vs Q4328 vs Q4329 vs 15271: national Medicare rates
Swap in your local Medicare rate.
How to choose
- Q4328Wound product
- Q4328 identifies Most, while Q4327 identifies Duoamnion. The product documentation determines which code to report.
- Q4329Wound graft
- Q4329 identifies Singlay, not Duoamnion. Do not select between them based only on the shared per-square-centimeter unit.
- 15271Skin substitute graft
- 15271 reports a primary skin-substitute application procedure; Q4327 reports the Duoamnion product as an add-on. The appropriate application code depends on the wound site and area.
Q4327 billing questions
What distinguishes Q4327 from another per-square-centimeter graft code?
Q4327 identifies Duoamnion specifically. Select the code that matches the product record rather than choosing among graft codes by unit of measure alone.
Can Q4327 be billed by itself?
No. CMS identifies it as an add-on code that must be reported with a primary procedure; an appropriate skin-substitute application procedure is a common pairing.
How should units be determined?
The code is measured per square centimeter. The product and wound documentation should support the square centimeters reported.
Does Q4327 include interpretation?
No. CMS classifies Q4327 as technical-component-only and indicates that a separate code covers interpretation.
What documentation supports reporting Q4327?
Document the Duoamnion product used, the wound treated, the application procedure, and the square centimeters furnished.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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