$62.39–$68.12
Choose 78110 when the study determines plasma volume alone; 78122 is for determination of whole blood volume.
On this page
CMS RVU26D · Effective 2026-10-01
78122 Blood volume test Medicare reimbursement rates in Missouri
A nuclear medicine blood volume study measures circulating whole blood volume when a clinician needs a direct assessment beyond routine blood counts. Compare 78122 office and facility rates across CMS payment localities in Missouri.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for 78122 in Missouri?
Missouri has 3 payment localities in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the 3 payment areas shown below, using the same CMS release.
Office / nonfacility
$89.49–$97.15
3 of 3 localities have a supported rate.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Where 78122 pays more and less in Missouri
3 payment localities
$89.49 to $97.15
Nuclear medicine
About 78122: Whole blood volume study
A nuclear medicine blood volume study measures circulating whole blood volume when a clinician needs a direct assessment beyond routine blood counts.
This study uses a tracer-dilution technique to estimate circulating whole blood volume from patient samples and measurement of the tracer. It is typically performed in a hospital nuclear medicine department, with a nuclear medicine technologist handling the technical procedure and a physician interpreting the results. Clinicians may request it when evaluating suspected abnormalities in circulating blood volume, including certain hematologic disorders.
Report 78122 when the service determines whole blood volume, rather than only plasma volume or red cell mass. The record should support the clinical reason for testing, the tracer and sampling procedure performed, the measurements used, and the physician’s interpretation. CMS recognizes professional and technical components: report modifier 26 for the interpretation, modifier TC for the equipment and staff portion, or neither modifier when billing the global service. CMS separately prices the 26 and TC services.
CMS billing rules for 78122
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU0.44 · 15%
- Practice expense (office) RVU2.53 · 83%
- Malpractice RVU0.06 · 2%
312
Medicare services in 2024 · #3968 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
78122 compared with similar codes
Office rates for Missouri, from the same CMS release.
$84.65–$92.63
78111 is the multiple-sample plasma volume service. It does not represent whole blood volume determination.
$63.68–$69.44
78120 determines red cell mass. Report 78122 when the study determines whole blood volume instead.
Compare 78122 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
3 of 3 payment localities
Metropolitan Kansas City →
Office / nonfacility
$96.00
Facility
Unavailable
Metropolitan St. Louis →
Office / nonfacility
$97.15
Facility
Unavailable
Rest Of Missouri →
Office / nonfacility
$89.49
Facility
Unavailable
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78122 billing questions
How is 78122 different from a plasma volume study?
78122 determines whole blood volume. Use a plasma volume code when the measured quantity is plasma volume alone.
How is 78122 different from red cell mass testing?
78122 measures whole blood volume; red cell mass codes concern the circulating red cell component. Select the code that matches the quantity actually determined.
When should modifier 26 or TC be reported?
Use modifier 26 for the physician’s interpretation and report, or TC for the technical service involving equipment and staff. Bill without either modifier for the global service.
What documentation supports 78122?
Document the clinical indication, tracer and sampling procedure, measurements used to determine whole blood volume, and the interpreting physician’s findings.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
9,23378121,,Red cell mass multiple,A,,0.31,2.56,,2.56,NA,0.05,2.92,2.92,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
9,23478121,26,Red cell mass multiple,A,,0.31,0.12,,0.12,,0.01,0.44,0.44,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
9,23578121,TC,Red cell mass multiple,A,,0.00,2.44,,2.44,NA,0.04,2.48,2.48,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,01,0,99,0.00,0.00,0.00
9,23678122,,Whl bld volume determination,A,,0.44,2.53,,2.53,NA,0.06,3.03,3.03,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
9,23778122,26,Whl bld volume determination,A,,0.44,0.16,,0.16,,0.02,0.62,0.62,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
9,23878122,TC,Whl bld volume determination,A,,0.00,2.37,,2.37,NA,0.04,2.41,2.41,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,01,0,99,0.00,0.00,0.00
9,23978130,,Red cell survival study,A,,0.59,3.14,,3.14,NA,0.07,3.80,3.80,1,XXX,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00