Billing code 78122: Blood volume testMedicare rate & RVUs

A nuclear medicine blood volume study measures circulating whole blood volume when a clinician needs a direct assessment beyond routine blood counts.

CMS RVU26DEffective Oct 1, 2026109 payment localities312 Medicare services in 2024

Medicare pays $101.20 for 78122 nationally in the office. Local office rates run $88.32–$139.24.

Medicare rate · 78122

Blood volume test

Swap in your local Medicare rate.

Work RVUs
0.44
Total RVUs
3.03
Global days
XXX

National rate · 2026

$101.20

Office setting, before claim adjustments.

See every locality for 78122 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 78122 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 78122 covers

This study uses a tracer-dilution technique to estimate circulating whole blood volume from patient samples and measurement of the tracer. It is typically performed in a hospital nuclear medicine department, with a nuclear medicine technologist handling the technical procedure and a physician interpreting the results. Clinicians may request it when evaluating suspected abnormalities in circulating blood volume, including certain hematologic disorders.

Report 78122 when the service determines whole blood volume, rather than only plasma volume or red cell mass. The record should support the clinical reason for testing, the tracer and sampling procedure performed, the measurements used, and the physician’s interpretation. CMS recognizes professional and technical components: report modifier 26 for the interpretation, modifier TC for the equipment and staff portion, or neither modifier when billing the global service. CMS separately prices the 26 and TC services.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 78122 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$88.32 to $139.24

$88.32$113.78$139.24
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

78122 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$89.77Unavailable
Alaska*$113.15Unavailable
Arizona$98.30Unavailable
Arkansas$88.32Unavailable
Atlanta$103.00Unavailable
Austin$105.91Unavailable
Bakersfield$108.81Unavailable
Baltimore/Surr. Cntys$108.08Unavailable
Beaumont$93.46Unavailable
Brazoria$100.12Unavailable

78122 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$88.32

$123.94

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
78122 office rate range by state
State / territoryOffice rate rangeLocalities
AK$113.151
AL$89.771
AR$88.321
AZ$98.301
CA$108.64–$139.2429
CO$106.351
CT$108.431
DC$117.271
DE$100.061
FL$98.49–$107.733
GA$92.46–$103.002
GU$111.941
HI$111.941
IA$92.811
ID$93.391
IL$94.98–$105.144
IN$94.011
KS$92.101
KY$91.651
LA$91.40–$96.492
MA$105.51–$117.982
MD$102.20–$117.273
ME$93.69–$99.702
MI$94.11–$99.622
MN$102.241
MO$89.49–$97.153
MS$88.941
MT$101.201
NC$94.821
ND$100.011
NE$93.451
NH$104.421
NJ$109.76–$115.792
NM$94.591
NV$100.951
NY$96.38–$119.835
OH$93.871
OK$91.721
OR$100.27–$110.312
PA$94.17–$105.322
PR$102.101
RI$104.061
SC$94.481
SD$99.871
TN$92.591
TX$93.46–$105.918
UT$95.931
VA$99.18–$117.272
VI$102.101
VT$99.371
WA$105.40–$120.762
WI$96.271
WV$91.001
WY$100.681

How the 78122 rate is calculated

Each of 78122’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 78122

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.44Practice expense 2.53Malpractice 0.06

3.0300 adjusted RVUs×$33.4009 conversion factor=$101.20

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 78122

The CMS indicators that decide how 78122 is paid alongside other services.

CMS payment indicators · 78122

Blood volume test

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

78122 without 26 · national office

$101.20

Blood volume test

78122-26 · Professional component

$20.71

Pays only the interpretation and report.

When to use modifier 26

78122 compared with similar codes

Compare codes

78122 vs 78110 vs 78111 vs 78120: national Medicare rates

Swap in your local Medicare rate.

  • 78122
    Blood volume test · 0.44 wRVU
    $101.20
  • 78110
    Plasma volume · 0.19 wRVU
    $71.14−$30.06
  • 78111
    Plasma volume · 0.21 wRVU
    $96.86−$4.34
  • 78120
    Red cell mass · 0.22 wRVU
    $72.48−$28.72

How to choose

78110Plasma volume
Choose 78110 when the study determines plasma volume alone; 78122 is for determination of whole blood volume.
78111Plasma volume
78111 is the multiple-sample plasma volume service. It does not represent whole blood volume determination.
78120Red cell mass
78120 determines red cell mass. Report 78122 when the study determines whole blood volume instead.

78122 billing questions

How is 78122 different from a plasma volume study?

78122 determines whole blood volume. Use a plasma volume code when the measured quantity is plasma volume alone.

How is 78122 different from red cell mass testing?

78122 measures whole blood volume; red cell mass codes concern the circulating red cell component. Select the code that matches the quantity actually determined.

When should modifier 26 or TC be reported?

Use modifier 26 for the physician’s interpretation and report, or TC for the technical service involving equipment and staff. Bill without either modifier for the global service.

What documentation supports 78122?

Document the clinical indication, tracer and sampling procedure, measurements used to determine whole blood volume, and the interpreting physician’s findings.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 78122PPRRVU2026_Oct_nonQPP.csv, line 9,236 (RVU26D)

Open CMS sourceHow we calculate rates

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