$117.46
Q4221 identifies AmnioWrap2; Q4227 identifies Amniocore. Select the code matching the product used, not simply the wound area.
On this page
CMS RVU26D · Effective 2026-10-01
Q4227 Amniocore Medicare reimbursement rates in Nebraska
Report Amniocore per square centimeter when this amniotic membrane product is applied with a primary wound procedure, such as treatment of an ulcer. Compare Q4227 office and facility rates across CMS payment localities in Nebraska.
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
What does Medicare pay for Q4227 in Nebraska?
Nebraska has 1 payment locality in this comparison. Use the service location to choose the applicable amount. These are the supported base rates for the payment area shown below, using the same CMS release.
Office / nonfacility
$117.46
1 of 1 localities have a supported rate.
Payment area: Nebraska
One mapped payment locality.
Facility setting
No supported rate
These are locality ranges, not averages or address-specific quotes. A facility-setting amount covers the physician service; it does not include a hospital’s separate bill. Choose a locality below to inspect its calculation, compare other payment areas, or price a percentage of Medicare.
Wound care biologic
About Q4227: Amniocore wound membrane supply
Report Amniocore per square centimeter when this amniotic membrane product is applied with a primary wound procedure, such as treatment of an ulcer.
Amniocore is an amniotic membrane product reported by the square centimeter when used as part of wound treatment. Wound care clinicians and surgeons may apply it to a prepared wound in an outpatient clinic, hospital department, or surgical setting. Examples include chronic ulcers and surgical wounds; the product supply is distinct from the procedure that prepares and treats the wound.
Report Q4227 with the primary procedure that applies the product, using the quantity of Amniocore applied. Documentation should identify the product, wound site, treated area, and quantity so the reported units can be supported. CMS classifies this as an add-on code paid within the primary procedure’s global period. It is technical-component-only; a separate code covers interpretation. Its CMS relative-value profile assigns practice expense and no physician work RVU.
CMS billing rules for Q4227
- Global period
- Add-on code: billed only together with a primary procedure and paid within that procedure's global period.
- Professional and technical components
- Technical-component-only code: a separate code covers interpretation.
Where the value comes from
- Work RVU0.00 · 0%
- Practice expense (office) RVU3.81 · 100%
- Malpractice RVU0.00 · 0%
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4227 compared with similar codes
Office rates for Nebraska, from the same CMS release.
$117.46
Q4229 identifies Cogenex amniotic membrane, while Q4227 identifies Amniocore. The product name determines which supply code applies.
Q4226
No office rateMyown harv prep proc sq cm
Q4226 describes the MyOwn harvest and preparation process. Q4227 reports Amniocore product by square centimeter.
Compare Q4227 by payment locality
Find the payment area for your service address, then open its rate page for calculation inputs, release history and the percentage-of-Medicare tool. A city may cross payment-area boundaries; the ZIP lookup above helps resolve the location.
1 of 1 payment localities
Nebraska →
Office / nonfacility
$117.46
Facility
Unavailable
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How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for Q4227 in Nebraska.
PPRRVU2026_Oct_nonQPP.csv
18,318
- Code
- Q4227
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
72
- Locality
- Nebraska
- Physician work
- 1.000
- Practice expense
- 0.923
- Malpractice
- 0.378
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.000 | 0.0000 |
| Practice expense | 3.81 | × 0.923 | 3.5166 |
| Malpractice | 0.00 | × 0.378 | 0.0000 |
| Total RVUs | 3.5166 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Nebraska$117.46
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0 | 1 |
| Practice expense | 3.81 | 0.923 |
| Malpractice | 0 | 0.378 |
(0 × 1 + 3.81 × 0.923 + 0 × 0.378) × $33.4009 = $117.46
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
Q4227 billing questions
Can Q4227 be reported by itself?
No. CMS identifies Q4227 as an add-on code that must be billed with a primary procedure.
How is the quantity reported?
The descriptor is per square centimeter. Document the Amniocore quantity applied and the treated wound area to support the reported units.
Does Q4227 include interpretation?
No. It is a technical-component-only code, and a separate code covers interpretation.
What documentation supports Q4227?
Record the Amniocore product, wound site, treated area, quantity applied, and the primary procedure performed.
How does the global period affect payment?
CMS pays Q4227 within the global period of the primary procedure; it is not a stand-alone procedure code.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
18,315Q4224,,Hhf10-p per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,316Q4225,,"Amnio or derma tl, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,317Q4226,,Myown harv prep proc sq cm,E,,0.00,0.00,,0.00,,0.00,0.00,0.00,9,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
18,318Q4227,,Amniocore per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,319Q4229,,Cogenex amnio memb per sq cm,A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
18,320Q4230,,Cogenex flow amnion 0.5 cc,C,,0.00,0.00,,0.00,,0.00,0.00,0.00,3,XXX,0.00,0.00,0.00,9,9,9,9,9,9,,33.4009,09,0,99,0.00,0.00,0.00
18,321Q4232,,"Corplex, per sq cm",A,,0.00,3.81,,3.81,NA,0.00,3.81,3.81,3,ZZZ,0.00,0.00,0.00,0,0,0,0,0,9,,33.4009,09,0,99,0.00,0.00,0.00
6905302,MO,01,METROPOLITAN ST. LOUIS,1.000,0.952,1.002
7005302,MO,99,REST OF MISSOURI,1.000,0.862,0.974
7103202,MT,01,MONTANA**,1.000,1.000,0.998
7205402,NE,00,NEBRASKA,1.000,0.923,0.378
7301312,NV,00,NEVADA**,1.000,1.001,0.833
7414312,NH,40,NEW HAMPSHIRE,1.000,1.041,0.875
7512402,NJ,01,NORTHERN NJ,1.063,1.160,1.068