HCPCS Q4377: Skin substituteMedicare rate & RVUs in Ohio

Report Q4377 for Trigraft supplied for wound coverage, measured in square centimeters and billed with the applicable primary application procedure.

CMS RVU26DEffective Oct 1, 20261 payment locality

Medicare pays $116.19 for Q4377 in the office in Ohio (Ohio). Which amount applies depends on the service address.

$116.19Office (non-facility)
—Hospital or facility

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open Q4377 for the payment locality that covers the ZIP.

On this page 9 sections
  1. Rate in Ohio
  2. What Q4377 covers
  3. By payment locality
  4. How it’s calculated
  5. Payment rules
  6. Similar codes
  7. Related codes
  8. Billing questions
  9. Sources

What Q4377 covers

Q4377 identifies the Trigraft product supplied for wound coverage, with reporting based on square centimeters. A wound-care clinician, surgeon, or other treating practitioner may use the product during a wound-care encounter after preparing the wound bed. The HCPCS code identifies the product, not the clinical work of preparing the site or applying the material.

Report the quantity supported by the product used, and document the product identity, wound site, area treated, and associated application procedure. Q4377 is an add-on code: submit it only with a primary procedure, and its payment falls within that procedure’s global period. CMS classifies it as technical-component-only; a separate code covers interpretation. The applicable primary procedure depends on the wound location and treated area, so the product code does not replace the application service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Q4377 in Ohio

Q4377 office and facility rates by payment locality
Payment localityOfficeFacility
Ohio$116.19Unavailable

How the Q4377 rate is calculated

Each of Q4377’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4377

RVUs × geographic indexes × conversion factor

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4377

The CMS indicators that decide how Q4377 is paid alongside other services.

CMS payment indicators · Q4377

Skin substitute

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4377 compared with similar codes

Compare codes · National

4 codes, side by side

  • Q4377

    Skin substitute0 wRVU

    $127.26

  • Q4378

    Wound matrix0 wRVU

    $127.26+$0.00

  • Q4379

    Wound graft0 wRVU

    $127.26+$0.00

  • 15271

    Skin substitute graft1.46 wRVU

    $157.99+$30.73

How to choose

Q4378Wound matrix
Q4378 identifies Renew FT Matrix, while Q4377 identifies Trigraft. Select the code for the product supplied; both descriptors use square-centimeter units.
Q4379Wound graft
Q4379 identifies Amniodefend FT rather than Trigraft. The product identity, not the wound’s size alone, distinguishes these codes.
15271Skin substitute graft
15271 reports the primary application service for specified wound locations and area; Q4377 identifies the Trigraft product used with a primary procedure.

Q4377 billing questions

How is Q4377 different from another skin-substitute product code?

Q4377 identifies Trigraft specifically. Use the code matching the product actually supplied rather than choosing among product codes based only on wound size or location.

Is Q4377 reported by wound or by square centimeter?

The descriptor is per square centimeter. Document the product quantity used in square centimeters and the area treated.

Can Q4377 be billed by itself?

No. CMS identifies it as an add-on code that must be billed with a primary procedure.

Does Q4377 include the wound application service?

No. Q4377 identifies the Trigraft product. Report the applicable primary application procedure for the clinical service.

How does the global-period rule affect Q4377?

Payment for Q4377 falls within the primary procedure’s global period. Submit it with that primary procedure rather than as a standalone service.

What does the technical-component designation mean here?

CMS classifies Q4377 as technical-component-only, with interpretation covered by a separate code.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4377PPRRVU2026_Oct_nonQPP.csv, line 18,463 (RVU26D)
Geographic factors for OhioGPCI2026.csv, line 85 (RVU26D)

Open CMS sourceHow we calculate rates

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