HCPCS code Q4391: Wound product2026 Medicare rate & RVUs in Ohio
Q4391 reports Amnioplast Double by square centimeter as a wound product supplied with a separately reported skin-substitute application procedure.
Medicare pays $116.19 for Q4391 in the office in Ohio (Ohio). Which amount applies depends on the service address.
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 9 sections
What Q4391 covers
Q4391 identifies the Amnioplast Double wound product by surface area. It represents the product, not the clinician’s work to prepare the wound or apply the material. Wound-care clinicians may use this type of product in outpatient treatment of chronic wounds, including diabetic foot and venous leg ulcers. The application procedure is reported separately using the code that fits the wound site and treated area.
Report the quantity in square centimeters and retain documentation identifying the product and the amount used. CMS classifies Q4391 as an add-on: it must be billed with a primary procedure, and payment falls within that procedure’s global period. CMS also classifies it as technical-component-only; a separate code covers interpretation. The record should support both the product quantity and the separately reported application service.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Q4391 in Ohio
| Payment locality | Office | Facility |
|---|---|---|
| Ohio | $116.19 | Unavailable |
How the Q4391 rate is calculated
Each of Q4391’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4391
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for Q4391
The CMS indicators that decide how Q4391 is paid alongside other services.
CMS payment indicators · Q4391
Wound product
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
Q4391 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 15271Skin substitute graft
- This CPT code reports application of a skin substitute for its specified site and area; Q4391 reports the Amnioplast Double product by square centimeter.
- Q4392Skin substitute
- Q4392 identifies Grafix Duo, a different product. Use the code matching the product supplied rather than choosing by wound type alone.
- Q4379Wound graft
- Q4379 identifies AmnioDefend. Q4391 is specific to Amnioplast Double, even though both are wound-product codes.
Q4391 billing questions
Does Q4391 include applying the product?
No. Q4391 reports the Amnioplast Double product; report the applicable skin-substitute application procedure separately.
What procedure must accompany Q4391?
It must be billed with a primary procedure. For wound treatment, the application code depends on the wound site and treated area.
How is the quantity reported?
Q4391 is billed by square centimeter. Document the product used and the supported quantity in the clinical and billing records.
How does the global-period rule affect payment?
CMS treats Q4391 as an add-on paid within the primary procedure’s global period, so it is not a stand-alone service.
Does this code include interpretation?
No. CMS classifies Q4391 as technical-component-only; a separate code covers interpretation.
Is Q4391 interchangeable with another amniotic wound product code?
No. Select Q4391 when the product supplied is Amnioplast Double; another product’s HCPCS code identifies that distinct product.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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