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CPT code 41108: Oral biopsy, floor of mouth2026 Medicare rate & RVUs in Virginia

Report this service when a clinician biopsies a lesion or abnormal tissue arising from the floor of the mouth for diagnostic evaluation.

CMS RVU26DEffective Oct 1, 2026One payment locality966 Medicare services in 2024

In Virginia, Medicare pays $166.34 for 41108 in the office and $81.96 when it’s performed in a hospital or facility.

$166.34Office (non-facility)
$81.96Hospital or facility
−2.2%vs the national office rate ($170.01)

Check a contract rate as a % of Medicare · 41108 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 41108 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Virginia
  2. What 41108 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 41108 covers

A clinician removes a tissue sample from the floor of the mouth for diagnostic examination, often when an oral lesion or unexplained tissue change needs evaluation. Oral and maxillofacial surgeons, otolaryngologists, and other clinicians qualified to perform oral procedures may do the biopsy in an office or facility. The specimen is generally submitted for pathologic examination; the biopsy code describes the tissue-sampling procedure, not the pathology interpretation.

Select this code for a biopsy at the floor of the mouth, rather than a biopsy of the tongue or an excision of a lesion. The operative note should identify the sampled site and document that tissue was obtained for diagnosis. CMS assigns a 10-day global period, so related postoperative visits during that period are included. When multiple procedures are performed in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% reduction. Do not use modifier 50 for this anatomy. CMS does not pay an assistant at surgery, and co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Virginia compares for 41108

Across 109 of 109 payment localities, the office rate for 41108 runs from $149.35 in Arkansas to $228.75 in San Benito County, CA. Virginia pays $166.34. The RVUs are the same everywhere; the geographic indexes change the dollars.

41108 in Virginia vs other payment areas
  1. Virginia · this page$166.34
  2. Los Angeles, CA · California$193.45+$27.11
  3. Washington, DC area · District of Columbia$195.52+$29.18
  4. Miami, FL · Florida$182.97+$16.63
  5. Chicago, IL · Illinois$177.40+$11.06
  6. Manhattan, NY · New York$196.17+$29.83
  7. Alaska · Alaska$194.03+$27.69

Other areas in Virginia first, then benchmark localities. Bars start at $0.

Every other payment area

41108 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$151.68$76.57
ArkansasArkansas$149.35$75.62
ArizonaArizona$165.28$82.10
Bakersfield, CACalifornia$181.14$87.06
Chico, CACalifornia$180.70$86.62
El Centro, CACalifornia$180.73$86.65
Fresno, CACalifornia$180.70$86.62
Hanford, CACalifornia$180.70$86.62

41108 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$149.35

$204.73

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
41108 office rate range by state
State / territoryOffice rate rangeLocalities
AK$194.031
AL$151.681
AR$149.351
AZ$165.281
CA$180.70–$228.7529
CO$177.611
CT$181.731
DC$195.521
DE$168.131
FL$166.84–$182.973
GA$157.01–$173.192
GU$185.611
HI$185.611
IA$156.001
ID$157.031
IL$161.59–$177.624
IN$158.001
KS$155.121
KY$155.241
LA$154.94–$163.072
MA$176.42–$196.002
MD$171.51–$195.523
ME$157.78–$167.002
MI$159.41–$168.922
MN$170.231
MO$152.04–$163.823
MS$150.741
MT$170.001
NC$159.541
ND$167.031
NE$156.941
NH$174.681
NJ$183.82–$193.282
NM$160.291
NV$169.301
NY$162.06–$201.025
OH$158.801
OK$155.061
OR$168.01–$183.652
PA$159.14–$176.922
PR$171.361
RI$174.411
SC$159.441
SD$166.681
TN$155.931
TX$158.02–$177.018
UT$161.741
VA$166.34–$195.522
VI$171.361
VT$166.241
WA$176.13–$200.222
WI$161.111
WV$155.241
WY$168.711

See 41108 in every payment locality

How the 41108 rate is calculated

Each of 41108’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 41108

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.07

1.07 RVUs× 1.000 GPCI

Practice expense3.87

3.87 RVUs× 1.000 GPCI

Malpractice0.15

0.15 RVUs× 1.000 GPCI

Adjusted RVUs

5.0900

Conversion factor

$33.4009

Medicare rate

$170.01

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Virginia inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

4,897

Code
41108
Physician work
1.07
Practice expense
3.87
Malpractice
0.15

GPCI2026.csv

106

Locality
Virginia
Physician work
1.000
Practice expense
0.983
Malpractice
0.706
Office calculation for 41108 in Virginia
ComponentRVULocality factorAdjusted
Physician work1.07× 1.0001.0700
Practice expense3.87× 0.9833.8042
Malpractice0.15× 0.7060.1059
Total RVUs4.9801
Conversion factor× 33.4009

Office rate, Virginia$166.34

Office: (1.07 × 1 + 3.87 × 0.983 + 0.15 × 0.706) × $33.4009 = $166.34

Facility: (1.07 × 1 + 1.3 × 0.983 + 0.15 × 0.706) × $33.4009 = $81.96

Open 41108 in the RVU calculator

Payment rules and modifiers for 41108

41108 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 41108

Oral biopsy, floor of mouth

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 41108

Oral biopsy, floor of mouth

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

41108 without 51 · national office

$170.01

Oral biopsy, floor of mouth

41108-51 · Second procedure: 50%

$85.01

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 41108

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 41108
CodeHow it relatesOffice range, Virginia
Used instead
41100Tongue biopsy, anterior two-thirdsUse for biopsy of tongue tissue rather than tissue from the floor of the mouth.$183.88
41105Tongue biopsy, posterior one-thirdA tongue-biopsy option when the sampled site is the tongue, not the floor of the mouth.$185.13
41116Oral lesion excision, floor of mouthRepresents excision of a mouth lesion when the procedure removes the lesion rather than sampling tissue.$327.71
40808Mouth biopsy, oral vestibuleBiopsy option for a lesion in the vestibule of the mouth, a different anatomic site.$164.43
Often billed with
88305Tissue pathology exam, level IV specimenPathology may separately report examination of the submitted biopsy specimen.$69.18

How 41108 has changed in Virginia

41108 · Office / nonfacility

$166.34

Effective 2026-10-01

The base rate is $6.47 higher than on 2025-10-01, moving from $159.87 to $166.34 (4.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $159.87changed to$166.34

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.10 changed to 1.07
    • Practice expense RVU 3.78 changed to 3.87
    • Malpractice RVU 0.16 changed to 0.15
    • Work GPCI 1.002 changed to 1.000
    • Practice expense GPCI 0.984 changed to 0.983
    • Malpractice GPCI 0.755 changed to 0.706

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $165.58changed to$159.87

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 3.82 changed to 3.78
    • Malpractice RVU 0.15 changed to 0.16

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $162.88changed to$165.58

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $170.52changed to$162.88

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 3.83 changed to 3.82
    • Malpractice RVU 0.17 changed to 0.15
    • Work GPCI 1.000 changed to 1.002
    • Practice expense GPCI 0.990 changed to 0.984
    • Malpractice GPCI 0.826 changed to 0.755

  5. January 1, 2023

    RVU23A

    $172.91changed to$170.52

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 3.79 changed to 3.83
    • Malpractice RVU 0.14 changed to 0.17
    • Practice expense GPCI 0.995 changed to 0.990
    • Malpractice GPCI 0.897 changed to 0.826

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $171.19changed to$172.91

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 3.69 changed to 3.79
    • Malpractice RVU 0.15 changed to 0.14

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $158.38changed to$171.19

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 3.20 changed to 3.69
    • Malpractice RVU 0.13 changed to 0.15
    • Practice expense GPCI 0.991 changed to 0.995
    • Malpractice GPCI 0.903 changed to 0.897

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $155.36changed to$158.38

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 3.10 changed to 3.20
    • Malpractice RVU 0.17 changed to 0.13
    • Practice expense GPCI 0.986 changed to 0.991
    • Malpractice GPCI 0.908 changed to 0.903

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $151.29changed to$155.36

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 2.99 changed to 3.10

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $151.17changed to$151.29

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 3.01 changed to 2.99
    • Practice expense GPCI 0.985 changed to 0.986
    • Malpractice GPCI 0.866 changed to 0.908

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $151.75changed to$151.17

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 3.05 changed to 3.01
    • Practice expense GPCI 0.983 changed to 0.985
    • Malpractice GPCI 0.824 changed to 0.866

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $151.94changed to$151.75

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 3.04 changed to 3.05

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $151.19changed to$151.94

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $150.10changed to$151.19

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 3.05 changed to 3.04
    • Malpractice RVU 0.13 changed to 0.17
    • Practice expense GPCI 0.980 changed to 0.983
    • Malpractice GPCI 0.778 changed to 0.824

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $152.93changed to$150.10

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 3.37 changed to 3.05
    • Malpractice RVU 0.14 changed to 0.13
    • Practice expense GPCI 0.977 changed to 0.980
    • Malpractice GPCI 0.731 changed to 0.778

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $152.93

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$166.34$81.96RVU26D
2026-07-01$166.34$81.96RVU26C
2026-04-01$166.34$81.96RVU26B
2026-01-01$166.34$81.96RVU26A
2025-10-01$159.87$88.26RVU25D
2025-07-01$159.87$88.26RVU25C
2025-04-01$159.87$88.26RVU25B
2025-01-01$159.87$88.26RVU25A
2024-10-01$165.58$89.92RVU24D
2024-07-01$165.58$89.92RVU24C
2024-04-01$165.58$89.92RVU24B
2024-03-09$165.58$89.92RVU24AR
2024-01-01$162.88$88.45RVU24A
2023-10-01$170.52$91.69RVU23D
2023-07-01$170.52$91.69RVU23C
2023-04-01$170.52$91.69RVU23B
2023-01-01$170.52$91.69RVU23A
2022-10-01$172.91$91.31RVU22D
2022-07-01$172.91$91.31RVU22C
2022-04-01$172.91$91.31RVU22B
2022-01-01$172.91$91.31RVU22A
2021-10-01$171.19$92.03RVU21D
2021-07-01$171.19$92.03RVU21C
2021-04-01$171.19$92.03RVU21B
2021-01-01$171.19$92.03RVU21A
2020-10-01$158.38$90.07RVU20D
2020-07-01$158.38$90.07RVU20C
2020-04-01$158.38$90.07RVU20B
2020-01-01$158.38$90.07RVU20A
2019-10-01$155.36$91.76RVU19D
2019-07-01$155.36$91.76RVU19C
2019-04-01$155.36$91.76RVU19B
2019-01-01$155.36$91.76RVU19A
2018-10-01$151.29$92.37RVU18D
2018-07-01$151.29$92.37RVU18C
2018-04-01$151.29$92.37RVU18B
2018-01-01$151.29$92.37RVU18AR1
2017-10-01$151.17$93.19RVU17D
2017-07-01$151.17$93.19RVU17C
2017-04-01$151.17$93.19RVU17B
2017-01-01$151.17$93.19RVU17A
2016-10-01$151.75$93.32RVU16D
2016-07-01$151.75$93.32RVU16C
2016-04-01$151.75$93.32RVU16B
2016-01-01$151.75$93.32RVU16A
2015-10-01$151.94$93.31RVU15D
2015-07-01$151.94$93.31RVU15C
2015-04-01$151.19$92.84RVU15B
2015-01-01$151.19$92.84RVU15A
2014-10-01$150.10$92.18RVU14D
2014-07-01$150.10$92.18RVU14C
2014-04-01$150.10$92.18RVU14B
2014-01-01$150.10$92.18RVU14A
2013-10-01$152.93$91.77RVU13D
2013-07-01$152.93$91.77RVU13C
2013-04-01$152.93$91.77RVU13B
2013-01-01$152.93$91.77RVU13AR

Price 41108 for an earlier date of service

Where the Virginia rate applies

Virginia is a Medicare payment area, not a city. Our Census mapping connects it to 628 cities and communities in Virginia. Some span more than one payment area; confirm with the service ZIP.

  • Abbs Valley
  • Abingdon
  • Accomac
  • Adwolf
  • Afton
  • Alberta
  • Aldie
  • Allison Gap

Browse all communities in Virginia

41108 billing questions

How is 41108 distinguished from a tongue biopsy?

Use 41108 when the sampled tissue is from the floor of the mouth. A biopsy of tongue tissue is coded according to the tongue site instead.

Can the pathology examination be reported separately?

The biopsy reports the clinician's tissue-sampling procedure. The pathologist's examination of the submitted specimen is a separate service when performed and reportable.

Is modifier 50 appropriate for bilateral floor-of-mouth biopsies?

No. CMS identifies bilateral adjustment as inappropriate for this code's descriptor and anatomy; do not append modifier 50.

What happens when another procedure is performed in the same session?

Under the standard multiple procedure reduction, the highest-valued procedure is paid in full and the other procedures are paid at 50% when performed in the same session.

Are assistant surgeons or co-surgeons payable for 41108?

CMS does not pay an assistant at surgery for this service. Co-surgeons and team surgery are not permitted.

Are related postoperative visits included?

Yes. The code has a 10-day global period, which includes related postoperative visits during those 10 days.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 41108PPRRVU2026_Oct_nonQPP.csv, line 4,897 (RVU26D)
Geographic factors for VirginiaGPCI2026.csv, line 106 (RVU26D)

Open CMS sourceHow we calculate rates

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