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CPT code 46916: Anal lesion treatment, cryosurgery, simple lesions2026 Medicare rate & RVUs in Minnesota

Reports simple destruction of anal lesion(s) by freezing, commonly for anal condylomata, when cryosurgery is the documented treatment method.

CMS RVU26DEffective Oct 1, 2026One payment locality561 Medicare services in 2024

In Minnesota, Medicare pays $254.85 for 46916 in the office and $119.09 when it’s performed in a hospital or facility.

$254.85Office (non-facility)
$119.09Hospital or facility
+0.3%vs the national office rate ($254.18)

Check a contract rate as a % of Medicare · 46916 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 46916 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Minnesota
  2. What 46916 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 46916 covers

Code 46916 represents destruction of one or more anal lesions by freezing, most commonly anal condylomata. A colorectal or general surgeon typically applies a cryogenic agent to the lesion or lesions in an office procedure room or a facility setting. The code is distinguished by the cryosurgical method and simple treatment level, rather than extensive destruction.

Report it when the clinician documents cryosurgery and an extent consistent with simple treatment. The record should identify the treated lesion(s), anal site, method, and extent. The 10-day global period includes related postoperative visits during that period. When multiple procedures subject to the standard reduction are performed in one session, the highest-valued procedure is paid in full and the others at 50%. Modifier 50 is inappropriate; assistant-at-surgery payment is barred by statutory restriction, and co-surgeon and team-surgery billing are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Minnesota compares for 46916

Across 109 of 109 payment localities, the office rate for 46916 runs from $224.80 in Arkansas to $339.85 in San Benito County, CA. Minnesota pays $254.85. The RVUs are the same everywhere; the geographic indexes change the dollars.

46916 in Minnesota vs other payment areas
  1. Minnesota · this page$254.85
  2. Los Angeles, CA · California$288.41+$33.56
  3. Washington, DC area · District of Columbia$291.29+$36.44
  4. Miami, FL · Florida$272.00+$17.15
  5. Chicago, IL · Illinois$264.19+$9.34
  6. Manhattan, NY · New York$292.10+$37.25
  7. Alaska · Alaska$294.29+$39.44

Other areas in Minnesota first, then benchmark localities. Bars start at $0.

Every other payment area

46916 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$228.11$112.67
ArkansasArkansas$224.80$111.47
ArizonaArizona$247.47$119.63
Bakersfield, CACalifornia$270.55$125.95
Chico, CACalifornia$269.93$125.33
El Centro, CACalifornia$269.97$125.37
Fresno, CACalifornia$269.93$125.33
Hanford, CACalifornia$269.93$125.33

46916 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$224.80

$304.89

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
46916 office rate range by state
State / territoryOffice rate rangeLocalities
AK$294.291
AL$228.111
AR$224.801
AZ$247.471
CA$269.93–$339.8529
CO$265.331
CT$271.101
DC$291.291
DE$251.591
FL$249.38–$272.003
GA$235.44–$258.682
GU$276.761
HI$276.761
IA$234.401
ID$235.831
IL$241.81–$264.784
IN$237.211
KS$233.071
KY$233.041
LA$232.58–$244.152
MA$263.64–$291.962
MD$256.48–$291.293
ME$236.83–$250.052
MI$238.91–$252.282
MN$254.851
MO$228.43–$245.303
MS$226.671
MT$254.171
NC$239.351
ND$250.211
NE$235.751
NH$260.951
NJ$274.37–$288.212
NM$240.141
NV$253.251
NY$242.93–$298.925
OH$238.111
OK$232.861
OR$251.46–$274.042
PA$238.61–$264.192
PR$256.121
RI$260.761
SC$239.091
SD$249.751
TN$234.221
TX$237.02–$264.308
UT$242.381
VA$249.07–$291.292
VI$256.121
VT$249.031
WA$263.22–$298.142
WI$241.771
WV$232.781
WY$252.441

See 46916 in every payment locality

How the 46916 rate is calculated

Each of 46916’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 46916

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.86

1.86 RVUs× 1.000 GPCI

Practice expense5.55

5.55 RVUs× 1.000 GPCI

Malpractice0.20

0.20 RVUs× 1.000 GPCI

Adjusted RVUs

7.6100

Conversion factor

$33.4009

Medicare rate

$254.18

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Minnesota inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

5,632

Code
46916
Physician work
1.86
Practice expense
5.55
Malpractice
0.20

GPCI2026.csv

66

Locality
Minnesota
Physician work
1.000
Practice expense
1.029
Malpractice
0.296
Office calculation for 46916 in Minnesota
ComponentRVULocality factorAdjusted
Physician work1.86× 1.0001.8600
Practice expense5.55× 1.0295.7109
Malpractice0.20× 0.2960.0592
Total RVUs7.6301
Conversion factor× 33.4009

Office rate, Minnesota$254.85

Office: (1.86 × 1 + 5.55 × 1.029 + 0.2 × 0.296) × $33.4009 = $254.85

Facility: (1.86 × 1 + 1.6 × 1.029 + 0.2 × 0.296) × $33.4009 = $119.09

Open 46916 in the RVU calculator

Payment rules and modifiers for 46916

46916 has a 10-day global period: related visits in that window are included in the surgery payment.

CMS payment indicators · 46916

Anal lesion treatment, cryosurgery, simple lesions

RuleCMS valueWhat it means
Global period010Minor procedure: the day of the procedure plus 10 days after are included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.
Split (54/55/56)0.10/0.80/0.10Share of the payment for pre-op, the procedure itself, and post-op care.

Global surgery period · 46916

Anal lesion treatment, cryosurgery, simple lesions

10-day global period ends

Oct 11, 2026

Covers Oct 1, 2026 through Oct 11, 2026 (11 days).

Visit on Oct 31, 2026

After the global period ends: visits and procedures are billed normally.

SurgeryVisit
Sep 28, 2026Oct 14, 2026

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

46916 without 51 · national office

$254.18

Anal lesion treatment, cryosurgery, simple lesions

46916-51 · Second procedure: 50%

$127.09

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 46916

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 46916
CodeHow it relatesOffice range, Minnesota
Same family
46900Anal lesion destruction, simple lesionsSimple anal lesion destruction using a chemical method rather than cryosurgery.$268.16
46910Anal lesion destruction, extensive lesionsSimple anal lesion destruction using an electrosurgical method.$296.05
46917Anal lesion laser, simple, laser surgerySimple anal lesion destruction using laser surgery.$468.83
46924Anal lesion destruction, extensive treatmentFor extensive anal lesion destruction, rather than simple cryosurgical treatment.$626.44
Used instead
46922Anal lesion excision, one or more lesionsRemoves anal lesion tissue rather than destroying it by freezing.$343.73

How 46916 has changed in Minnesota

46916 · Office / nonfacility

$254.85

Effective 2026-10-01

The base rate is $4.37 higher than on 2025-10-01, moving from $250.48 to $254.85 (1.7%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $250.48changed to$254.85

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.91 changed to 1.86
    • Practice expense RVU 5.63 changed to 5.55
    • Malpractice RVU 0.21 changed to 0.20
    • Practice expense GPCI 1.025 changed to 1.029
    • Malpractice GPCI 0.300 changed to 0.296

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $261.28changed to$250.48

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 5.73 changed to 5.63
    • Malpractice RVU 0.22 changed to 0.21

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $257.02changed to$261.28

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $264.80changed to$257.02

    • Conversion factor 33.8872 changed to 32.7442
    • Malpractice RVU 0.20 changed to 0.22
    • Practice expense GPCI 1.019 changed to 1.025
    • Malpractice GPCI 0.326 changed to 0.300

  5. January 1, 2023

    RVU23A

    $268.71changed to$264.80

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 5.71 changed to 5.73
    • Practice expense GPCI 1.013 changed to 1.019
    • Malpractice GPCI 0.353 changed to 0.326

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $264.45changed to$268.71

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 5.53 changed to 5.71
    • Malpractice RVU 0.19 changed to 0.20

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $250.58changed to$264.45

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 4.91 changed to 5.53
    • Malpractice RVU 0.18 changed to 0.19
    • Practice expense GPCI 1.012 changed to 1.013
    • Malpractice GPCI 0.357 changed to 0.353

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $242.02changed to$250.58

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 4.66 changed to 4.91
    • Malpractice RVU 0.26 changed to 0.18
    • Practice expense GPCI 1.011 changed to 1.012
    • Malpractice GPCI 0.362 changed to 0.357

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $234.11changed to$242.02

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 4.45 changed to 4.66

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $232.17changed to$234.11

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 4.40 changed to 4.45
    • Practice expense GPCI 1.016 changed to 1.011
    • Malpractice GPCI 0.341 changed to 0.362

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $230.95changed to$232.17

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 4.37 changed to 4.40
    • Practice expense GPCI 1.020 changed to 1.016
    • Malpractice GPCI 0.319 changed to 0.341

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $231.55changed to$230.95

    • Conversion factor 35.9335 changed to 35.8043
    • Malpractice RVU 0.24 changed to 0.26

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $230.40changed to$231.55

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $225.91changed to$230.40

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 4.25 changed to 4.37
    • Malpractice RVU 0.26 changed to 0.24
    • Practice expense GPCI 1.016 changed to 1.020
    • Malpractice GPCI 0.301 changed to 0.319

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $233.53changed to$225.91

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 4.82 changed to 4.25
    • Malpractice RVU 0.27 changed to 0.26
    • Practice expense GPCI 1.012 changed to 1.016
    • Malpractice GPCI 0.282 changed to 0.301

    Held through RVU14B, RVU14C, RVU14D.

  16. October 1, 2013

    RVU13D

    No ratechanged to$233.53

  17. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$254.85$119.09RVU26D
2026-07-01$254.85$119.09RVU26C
2026-04-01$254.85$119.09RVU26B
2026-01-01$254.85$119.09RVU26A
2025-10-01$250.48$136.10RVU25D
2025-07-01$250.48$136.10RVU25C
2025-04-01$250.48$136.10RVU25B
2025-01-01$250.48$136.10RVU25A
2024-10-01$261.28$139.13RVU24D
2024-07-01$261.28$139.13RVU24C
2024-04-01$261.28$139.13RVU24B
2024-03-09$261.28$139.13RVU24AR
2024-01-01$257.02$136.86RVU24A
2023-10-01$264.80$139.79RVU23D
2023-07-01$264.80$139.79RVU23C
2023-04-01$264.80$139.79RVU23B
2023-01-01$264.80$139.79RVU23A
2022-10-01$268.71$140.06RVU22D
2022-07-01$268.71$140.06RVU22C
2022-04-01$268.71$140.06RVU22B
2022-01-01$268.71$140.06RVU22A
2021-10-01$264.45$140.03RVU21D
2021-07-01$264.45$140.03RVU21C
2021-04-01$264.45$140.03RVU21B
2021-01-01$264.45$140.03RVU21A
2020-10-01$250.58$143.20RVU20D
2020-07-01$250.58$143.20RVU20C
2020-04-01$250.58$143.20RVU20B
2020-01-01$250.58$143.20RVU20A
2019-10-01$242.02$144.00RVU19D
2019-07-01$242.02$144.00RVU19C
2019-04-01$242.02$144.00RVU19B
2019-01-01$242.02$144.00RVU19A
2018-10-01$234.11$144.21RVU18D
2018-07-01$234.11$144.21RVU18C
2018-04-01$234.11$144.21RVU18B
2018-01-01$234.11$144.21RVU18AR1
2017-10-01$232.17$143.20RVU17D
2017-07-01$232.17$143.20RVU17C
2017-04-01$232.17$143.20RVU17B
2017-01-01$232.17$143.20RVU17A
2016-10-01$230.95$142.57RVU16D
2016-07-01$230.95$142.57RVU16C
2016-04-01$230.95$142.57RVU16B
2016-01-01$230.95$142.57RVU16A
2015-10-01$231.55$143.22RVU15D
2015-07-01$231.55$143.22RVU15C
2015-04-01$230.40$142.51RVU15B
2015-01-01$230.40$142.51RVU15A
2014-10-01$225.91$140.01RVU14D
2014-07-01$225.91$140.01RVU14C
2014-04-01$225.91$140.01RVU14B
2014-01-01$225.91$140.01RVU14A
2013-10-01$233.53$141.26RVU13D
2013-07-01Rate data unavailableRate data unavailableRVU13C
2013-04-01Rate data unavailableRate data unavailableRVU13B
2013-01-01Rate data unavailableRate data unavailableRVU13AR

Price 46916 for an earlier date of service

Where the Minnesota rate applies

Minnesota is a Medicare payment area, not a city. Our Census mapping connects it to 916 cities and communities in Minnesota. Some span more than one payment area; confirm with the service ZIP.

  • Ada
  • Adams
  • Adrian
  • Afton
  • Aitkin
  • Akeley
  • Albany
  • Albert Lea

Browse all communities in Minnesota

46916 billing questions

How does 46916 differ from 46900 or 46910?

46916 identifies cryosurgery. The neighboring codes distinguish other simple destruction methods, including chemical treatment and electrosurgical treatment.

When should extensive destruction be considered instead?

Use 46924 when the documented destruction is extensive. Code 46916 is for simple treatment by cryosurgery.

Can modifier 50 be reported?

No. The CMS bilateral adjustment does not apply to this code, and modifier 50 is inappropriate.

Are postoperative visits separately reported during the global period?

Related postoperative visits during the 10-day global period are included in the procedure.

How does Medicare apply the multiple-procedure reduction?

For qualifying procedures in the same session, the highest-valued procedure is paid in full and the others at 50%. Assistant-at-surgery payment is restricted, and co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 46916PPRRVU2026_Oct_nonQPP.csv, line 5,632 (RVU26D)
Geographic factors for MinnesotaGPCI2026.csv, line 66 (RVU26D)

Open CMS sourceHow we calculate rates

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