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CPT code 59015: Chorionic villus sampling, placental tissue sampling2026 Medicare rate & RVUs in South Carolina

Reports prenatal placental villus sampling to obtain fetal genetic material, typically during early pregnancy when diagnostic testing is indicated.

CMS RVU26DEffective Oct 1, 2026One payment locality

In South Carolina, Medicare pays $152.23 for 59015 in the office and $112.41 when it’s performed in a hospital or facility.

$152.23Office (non-facility)
$112.41Hospital or facility
−5.2%vs the national office rate ($160.66)

Check a contract rate as a % of Medicare · 59015 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 59015 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Carolina
  2. What 59015 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 59015 covers

A clinician obtains a small sample of chorionic villi from the placenta for prenatal diagnostic testing. Sampling may use a transcervical catheter or a transabdominal needle, with ultrasound used to guide the approach. Maternal-fetal medicine specialists and obstetricians commonly perform the procedure in an outpatient setting when testing for a fetal chromosomal or genetic condition is indicated.

Report 59015 for the sampling procedure, documenting the indication, approach, and specimen obtained. The genetic analysis is a separate laboratory service when performed and reported. Medicare assigns a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to a 50% reduction. Modifier 50 is inappropriate for this sampling. Assistant-at-surgery payment requires documented medical necessity; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Carolina compares for 59015

Across 109 of 109 payment localities, the office rate for 59015 runs from $140.32 in Arkansas to $198.10 in Miami, FL. South Carolina pays $152.23. The RVUs are the same everywhere; the geographic indexes change the dollars.

59015 in South Carolina vs other payment areas
  1. South Carolina · this page$152.23
  2. Los Angeles, CA · California$168.07+$15.84
  3. Washington, DC area · District of Columbia$178.87+$26.64
  4. Miami, FL · Florida$198.10+$45.87
  5. Chicago, IL · Illinois$190.90+$38.67
  6. Manhattan, NY · New York$189.28+$37.05
  7. Alaska · Alaska$190.67+$38.44

Other areas in South Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

59015 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$142.53$104.83
ArkansasArkansas$140.32$103.31
ArizonaArizona$155.34$113.59
Bakersfield, CACalifornia$159.49$112.27
Chico, CACalifornia$157.69$110.47
El Centro, CACalifornia$157.80$110.58
Fresno, CACalifornia$157.69$110.47
Hanford, CACalifornia$157.69$110.47

59015 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$140.32

$190.67

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
59015 office rate range by state
State / territoryOffice rate rangeLocalities
AK$190.671
AL$142.531
AR$140.321
AZ$155.341
CA$157.69–$187.2529
CO$160.781
CT$171.961
DC$178.871
DE$157.931
FL$169.17–$198.103
GA$157.88–$166.502
GU$160.161
HI$160.161
IA$141.341
ID$143.401
IL$167.69–$190.904
IN$144.161
KS$143.041
KY$151.391
LA$152.10–$159.852
MA$160.70–$173.932
MD$160.31–$178.873
ME$146.78–$151.682
MI$157.83–$173.922
MN$146.591
MO$150.94–$157.533
MS$145.541
MT$160.611
NC$148.031
ND$147.171
NE$141.441
NH$160.531
NJ$171.82–$177.312
NM$159.731
NV$156.931
NY$150.61–$197.225
OH$155.091
OK$148.521
OR$153.65–$163.332
PA$153.99–$169.052
PR$161.051
RI$161.751
SC$152.231
SD$145.581
TN$144.121
TX$153.09–$169.318
UT$154.371
VA$152.86–$178.872
VI$161.051
VT$148.781
WA$159.67–$175.102
WI$142.161
WV$161.781
WY$154.751

See 59015 in every payment locality

How the 59015 rate is calculated

Each of 59015’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 59015

RVUs × geographic indexes × conversion factor

Office or facility?

Work2.15

2.15 RVUs× 1.000 GPCI

Practice expense1.98

1.98 RVUs× 1.000 GPCI

Malpractice0.68

0.68 RVUs× 1.000 GPCI

Adjusted RVUs

4.8100

Conversion factor

$33.4009

Medicare rate

$160.66

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,627

Code
59015
Physician work
2.15
Practice expense
1.98
Malpractice
0.68

GPCI2026.csv

93

Locality
South Carolina
Physician work
1.000
Practice expense
0.924
Malpractice
0.850
Office calculation for 59015 in South Carolina
ComponentRVULocality factorAdjusted
Physician work2.15× 1.0002.1500
Practice expense1.98× 0.9241.8295
Malpractice0.68× 0.8500.5780
Total RVUs4.5575
Conversion factor× 33.4009

Office rate, South Carolina$152.23

Office: (2.15 × 1 + 1.98 × 0.924 + 0.68 × 0.85) × $33.4009 = $152.23

Facility: (2.15 × 1 + 0.69 × 0.924 + 0.68 × 0.85) × $33.4009 = $112.41

Open 59015 in the RVU calculator

Payment rules and modifiers for 59015

The CMS indicators that decide how 59015 is paid alongside other services.

CMS payment indicators · 59015

Chorionic villus sampling, placental tissue sampling

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

59015 without 51 · national office

$160.66

Chorionic villus sampling, placental tissue sampling

59015-51 · Second procedure: 50%

$80.33

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 59015

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 59015
CodeHow it relatesOffice range, South Carolina
Used instead
59000Amniocentesis, diagnostic fluid samplingDiagnostic amniotic-fluid sampling is an alternative prenatal testing procedure using a different specimen.$112.70
59012Cordocentesis, prenatal fetal blood samplingPrenatal fetal blood sampling is a different invasive diagnostic approach when fetal blood is needed.No office rate
Often billed with
76945CVS ultrasound guidance, during CVSReports ultrasound guidance for chorionic villus sampling when performed and documented.No office rate

How 59015 has changed in South Carolina

59015 · Office / nonfacility

$152.23

Effective 2026-10-01

The base rate is $7.22 higher than on 2025-10-01, moving from $145.01 to $152.23 (5.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $145.01changed to$152.23

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 2.20 changed to 2.15
    • Practice expense RVU 1.91 changed to 1.98
    • Malpractice RVU 0.66 changed to 0.68
    • Practice expense GPCI 0.913 changed to 0.924
    • Malpractice GPCI 0.817 changed to 0.850

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $149.47changed to$145.01

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 1.90 changed to 1.91
    • Malpractice RVU 0.68 changed to 0.66

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $147.03changed to$149.47

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $149.00changed to$147.03

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 1.87 changed to 1.90
    • Malpractice RVU 0.66 changed to 0.68
    • Practice expense GPCI 0.908 changed to 0.913
    • Malpractice GPCI 0.756 changed to 0.817

  5. January 1, 2023

    RVU23A

    $147.29changed to$149.00

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 1.80 changed to 1.87
    • Malpractice RVU 0.62 changed to 0.66
    • Practice expense GPCI 0.903 changed to 0.908
    • Malpractice GPCI 0.695 changed to 0.756

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $147.89changed to$147.29

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 1.78 changed to 1.80

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $148.88changed to$147.89

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 1.71 changed to 1.78
    • Malpractice RVU 0.60 changed to 0.62
    • Practice expense GPCI 0.907 changed to 0.903
    • Malpractice GPCI 0.624 changed to 0.695

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $146.65changed to$148.88

    • Conversion factor 36.0391 changed to 36.0896
    • Malpractice RVU 0.56 changed to 0.60
    • Practice expense GPCI 0.912 changed to 0.907
    • Malpractice GPCI 0.553 changed to 0.624

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $147.15changed to$146.65

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 1.73 changed to 1.71

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $148.22changed to$147.15

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 1.72 changed to 1.73
    • Malpractice RVU 0.57 changed to 0.56
    • Malpractice GPCI 0.634 changed to 0.553

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $149.27changed to$148.22

    • Conversion factor 35.8043 changed to 35.8887
    • Malpractice RVU 0.56 changed to 0.57
    • Malpractice GPCI 0.715 changed to 0.634

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $150.32changed to$149.27

    • Conversion factor 35.9335 changed to 35.8043
    • Malpractice RVU 0.58 changed to 0.56

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $149.57changed to$150.32

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $148.22changed to$149.57

    • Conversion factor 35.8228 changed to 35.7547
    • Malpractice RVU 0.60 changed to 0.58
    • Practice expense GPCI 0.911 changed to 0.912
    • Malpractice GPCI 0.618 changed to 0.715

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $144.14changed to$148.22

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 1.88 changed to 1.72
    • Malpractice RVU 0.63 changed to 0.60
    • Practice expense GPCI 0.909 changed to 0.911
    • Malpractice GPCI 0.520 changed to 0.618

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $144.14

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$152.23$112.41RVU26D
2026-07-01$152.23$112.41RVU26C
2026-04-01$152.23$112.41RVU26B
2026-01-01$152.23$112.41RVU26A
2025-10-01$145.01$120.50RVU25D
2025-07-01$145.01$120.50RVU25C
2025-04-01$145.01$120.50RVU25B
2025-01-01$145.01$120.50RVU25A
2024-10-01$149.47$124.24RVU24D
2024-07-01$149.47$124.24RVU24C
2024-04-01$149.47$124.24RVU24B
2024-03-09$149.47$124.24RVU24AR
2024-01-01$147.03$122.22RVU24A
2023-10-01$149.00$123.77RVU23D
2023-07-01$149.00$123.77RVU23C
2023-04-01$149.00$123.77RVU23B
2023-01-01$149.00$123.77RVU23A
2022-10-01$147.29$123.23RVU22D
2022-07-01$147.29$123.23RVU22C
2022-04-01$147.29$123.23RVU22B
2022-01-01$147.29$123.23RVU22A
2021-10-01$147.89$124.57RVU21D
2021-07-01$147.89$124.57RVU21C
2021-04-01$147.89$124.57RVU21B
2021-01-01$147.89$124.57RVU21A
2020-10-01$148.88$126.30RVU20D
2020-07-01$148.88$126.30RVU20C
2020-04-01$148.88$126.30RVU20B
2020-01-01$148.88$126.30RVU20A
2019-10-01$146.65$123.97RVU19D
2019-07-01$146.65$123.97RVU19C
2019-04-01$146.65$123.97RVU19B
2019-01-01$146.65$123.97RVU19A
2018-10-01$147.15$124.82RVU18D
2018-07-01$147.15$124.82RVU18C
2018-04-01$147.15$124.82RVU18B
2018-01-01$147.15$124.82RVU18AR1
2017-10-01$148.22$127.27RVU17D
2017-07-01$148.22$127.27RVU17C
2017-04-01$148.22$127.27RVU17B
2017-01-01$148.22$127.27RVU17A
2016-10-01$149.27$127.72RVU16D
2016-07-01$149.27$127.72RVU16C
2016-04-01$149.27$127.72RVU16B
2016-01-01$149.27$127.72RVU16A
2015-10-01$150.32$129.02RVU15D
2015-07-01$150.32$129.02RVU15C
2015-04-01$149.57$128.38RVU15B
2015-01-01$149.57$128.38RVU15A
2014-10-01$148.22$127.01RVU14D
2014-07-01$148.22$127.01RVU14C
2014-04-01$148.22$127.01RVU14B
2014-01-01$148.22$127.01RVU14A
2013-10-01$144.14$121.87RVU13D
2013-07-01$144.14$121.87RVU13C
2013-04-01$144.14$121.87RVU13B
2013-01-01$144.14$121.87RVU13AR

Price 59015 for an earlier date of service

Where the South Carolina rate applies

South Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 475 cities and communities in South Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Abney Crossroads
  • Adams Run
  • Aiken
  • Alcolu
  • Allendale
  • Anderson
  • Andrews

Browse all communities in South Carolina

59015 billing questions

How is chorionic villus sampling different from diagnostic amniocentesis?

59015 reports sampling placental villi, while 59000 reports sampling amniotic fluid. The appropriate procedure depends on the diagnostic method and specimen obtained.

Can ultrasound guidance be reported with 59015?

CPT 76945 describes ultrasound guidance for chorionic villus sampling. Report it when the guidance service is performed and documented.

Is the genetic laboratory analysis included in 59015?

No. Code 59015 represents obtaining the placental tissue; laboratory analysis is a distinct service when performed and reported.

Should modifier 50 be used for sampling from both sides of the placenta?

No. Modifier 50 is inappropriate for this procedure. Document the sampling performed and the approach used.

What same-session payment rules affect 59015?

Same-day preoperative and postoperative care is included in its 0-day global period. In a session with multiple procedures, the highest-valued procedure is paid in full and other procedures are subject to a 50% reduction.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 59015PPRRVU2026_Oct_nonQPP.csv, line 6,627 (RVU26D)
Geographic factors for South CarolinaGPCI2026.csv, line 93 (RVU26D)

Open CMS sourceHow we calculate rates

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