CPT code 88350: Immunofluorescence, each additional antibody stain2026 Medicare rate & RVUs in Connecticut

In Connecticut, Medicare pays $114.10 for 88350 in the office.

Check a contract rate as a % of Medicare · 88350 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 88350 covers

A pathology laboratory performs an additional immunofluorescence stain to detect a specific antibody or immune reactant in tissue. The pathologist interprets the staining pattern and reports the findings. Common settings include evaluation of renal biopsy tissue for immune deposits and direct immunofluorescence studies of skin biopsies when an autoimmune blistering disorder is suspected. Laboratory staff prepare and stain the tissue; the pathologist provides the diagnostic interpretation.

Report 88350 for each additional single-antibody stain after the first stain reported with 88346. The record should identify the tissue studied, the antibodies tested, and the results supporting each stain. This is an add-on code, so it is billed with its primary procedure and paid within that procedure’s global period. Modifier 26 identifies the professional interpretation, while modifier TC identifies the technical work, equipment, and staff; reporting without either modifier represents the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Connecticut compares for 88350

Across 109 of 109 payment localities, the office rate for 88350 runs from $94.31 in Arkansas to $147.09 in San Benito County, CA. Connecticut pays $114.10. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

88350 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 88350 in every payment locality

How the 88350 rate is calculated

Each of 88350’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 88350

The CMS indicators that decide how 88350 is paid alongside other services.

What modifiers do to the payment

When to use modifier 26

Codes related to 88350

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 88350 has changed in Connecticut

Price 88350 for an earlier date of service

Where the Connecticut rate applies

Connecticut is a Medicare payment area, not a city. Our Census mapping connects it to 215 cities and communities in Connecticut. Some span more than one payment area; confirm with the service ZIP.

• Ansonia
• Ball Pond
• Baltic
• Bantam
• Bethel
• Bethlehem Village
• Bigelow Corners
• Blue Hills

Browse all communities in Connecticut

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates