CPT code 88367: ISH analysis, automated morphometric analysis2026 Medicare rate & RVUs in Riverside, CA

Automated morphometric analysis of in situ hybridization signals in tissue helps quantify or assess a molecular finding, such as tumor gene amplification.

CMS RVU26DEffective Oct 1, 2026One payment locality4.6K Medicare services in 2024

In Riverside, CA, Medicare pays $112.94 for 88367 in the office.

$112.94Office (non-facility)
Not available in this settingHospital or facility
+7.7%vs the national office rate ($104.88)

Check a contract rate as a % of Medicare · 88367 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88367 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Riverside, CA
  2. What 88367 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88367 covers

This service covers automated morphometric analysis of in situ hybridization signals in a tissue specimen. A pathology laboratory uses imaging equipment and software to assess signal patterns, while a pathologist interprets the findings in the clinical and morphologic context. A familiar application is evaluating HER2 gene amplification in tumor tissue, including breast or gastric specimens, when the assay and analysis method support this code. It represents image-based analysis, not simply the preparation or staining of a probe slide.

Select the code based on the documented analysis method and the applicable CPT distinction between automated and manual analysis. The record should support the specimen analyzed, the in situ hybridization method, the automated analysis performed, and the pathologist’s interpretation. CMS recognizes professional and technical components: report modifier 26 for the interpretation, modifier TC for the equipment and staff, or neither modifier when billing the global service. The CMS fee schedule prices modifiers 26 and TC separately.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Riverside, CA compares for 88367

Across 109 of 109 payment localities, the office rate for 88367 runs from $93.20 in Arkansas to $142.76 in San Benito County, CA. Riverside, CA pays $112.94. The RVUs are the same everywhere; the geographic indexes change the dollars.

88367 in Riverside, CA vs other payment areas
  1. Riverside, CA · this page$112.94
  2. Bakersfield, CA · California$112.80−$0.14
  3. Chico, CA · California$112.70−$0.24
  4. El Centro, CA · California$112.70−$0.24
  5. Fresno, CA · California$112.70−$0.24
  6. Hanford, CA · California$112.70−$0.24
  7. Los Angeles, CA · California$120.36+$7.42

Other areas in California first, then benchmark localities. Bars start at $0.

Every other payment area

88367 in every other Medicare payment locality
Payment localityOfficeFacility
Madera, CACalifornia$112.70—
Merced, CACalifornia$112.70—
Modesto, CACalifornia$112.70—
Napa, CACalifornia$131.64—
Oxnard, CACalifornia$119.94—
Redding, CACalifornia$112.70—
Rest of CaliforniaCalifornia$112.70—
Sacramento, CACalifornia$118.54—

88367 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$93.20

$127.73

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88367 office rate range by state
State / territoryOffice rate rangeLocalities
AK$121.671
AL$94.531
AR$93.201
AZ$102.291
CA$112.70–$142.7629
CO$110.171
CT$111.691
DC$120.561
DE$103.961
FL$101.67–$109.203
GA$96.31–$106.372
GU$115.631
HI$115.631
IA$97.631
ID$98.091
IL$98.25–$107.734
IN$98.661
KS$96.821
KY$95.891
LA$95.59–$100.222
MA$109.39–$121.392
MD$106.03–$120.563
ME$98.19–$103.912
MI$97.96–$102.522
MN$106.741
MO$93.75–$101.023
MS$93.521
MT$104.881
NC$99.241
ND$104.481
NE$98.271
NH$108.101
NJ$113.30–$119.302
NM$98.331
NV$104.851
NY$100.66–$122.185
OH$97.881
OK$96.121
OR$104.36–$114.022
PA$98.24–$108.732
PR$105.751
RI$107.911
SC$98.661
SD$104.441
TN$97.241
TX$97.59–$109.528
UT$99.981
VA$103.31–$120.562
VI$105.751
VT$103.741
WA$109.29–$124.212
WI$101.041
WV$94.621
WY$104.711

See 88367 in every payment locality

How the 88367 rate is calculated

Each of 88367’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88367

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.71

0.71 RVUs× 1.000 GPCI

Practice expense2.41

2.41 RVUs× 1.000 GPCI

Malpractice0.02

0.02 RVUs× 1.000 GPCI

Adjusted RVUs

3.1400

Conversion factor

$33.4009

Medicare rate

$104.88

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Riverside, CA inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,294

Code
88367
Physician work
0.71
Practice expense
2.41
Malpractice
0.02

GPCI2026.csv

20

Locality
Riverside, CA
Physician work
1.018
Practice expense
1.096
Malpractice
0.853
Office calculation for 88367 in Riverside, CA
ComponentRVULocality factorAdjusted
Physician work0.71× 1.0180.7228
Practice expense2.41× 1.0962.6414
Malpractice0.02× 0.8530.0171
Total RVUs3.3812
Conversion factor× 33.4009

Office rate, Riverside, CA$112.94

Office: (0.71 × 1.018 + 2.41 × 1.096 + 0.02 × 0.853) × $33.4009 = $112.94

Open 88367 in the RVU calculator

Payment rules and modifiers for 88367

The CMS indicators that decide how 88367 is paid alongside other services.

CMS payment indicators · 88367

ISH analysis, automated morphometric analysis

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

88367 without 26 · national office

$104.88

ISH analysis, automated morphometric analysis

88367-26 · Professional component

$31.06

Pays only the interpretation and report.

When to use modifier 26

How 88367 has changed in Riverside, CA

88367 · Office / nonfacility

$112.94

Effective 2026-10-01

The base rate is $0.61 lower than on 2025-10-01, moving from $113.55 to $112.94 (0.5%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $113.55changed to$112.94

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.73 changed to 0.71
    • Practice expense RVU 2.51 changed to 2.41
    • Malpractice RVU 0.03 changed to 0.02
    • Work GPCI 1.014 changed to 1.018
    • Practice expense GPCI 1.093 changed to 1.096
    • Malpractice GPCI 0.892 changed to 0.853

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $119.83changed to$113.55

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 2.60 changed to 2.51
    • Malpractice RVU 0.02 changed to 0.03

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $117.87changed to$119.83

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $122.41changed to$117.87

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 2.64 changed to 2.60
    • Work GPCI 1.021 changed to 1.014
    • Practice expense GPCI 1.079 changed to 1.093
    • Malpractice GPCI 0.924 changed to 0.892
  5. January 1, 2023

    RVU23A

    $121.32changed to$122.41

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 2.57 changed to 2.64
    • Work GPCI 1.027 changed to 1.021
    • Practice expense GPCI 1.065 changed to 1.079
    • Malpractice GPCI 0.955 changed to 0.924

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $122.29changed to$121.32

    • Conversion factor 34.8931 changed to 34.6062
    • Malpractice GPCI 0.896 changed to 0.955

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $121.80changed to$122.29

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 2.44 changed to 2.57
    • Work GPCI 1.024 changed to 1.027
    • Practice expense GPCI 1.070 changed to 1.065
    • Malpractice GPCI 0.830 changed to 0.896

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $117.59changed to$121.80

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 2.33 changed to 2.44
    • Work GPCI 1.021 changed to 1.024
    • Practice expense GPCI 1.074 changed to 1.070
    • Malpractice GPCI 0.753 changed to 0.830

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $115.84changed to$117.59

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 2.29 changed to 2.33
    • Work GPCI 1.020 changed to 1.021
    • Malpractice GPCI 0.689 changed to 0.753

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $114.02changed to$115.84

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 2.24 changed to 2.29
    • Work GPCI 1.024 changed to 1.020
    • Practice expense GPCI 1.079 changed to 1.074
    • Malpractice GPCI 0.626 changed to 0.689

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    No ratechanged to$114.02

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$112.94Not available in this settingRVU26D
2026-07-01$112.94Not available in this settingRVU26C
2026-04-01$112.94Not available in this settingRVU26B
2026-01-01$112.94Not available in this settingRVU26A
2025-10-01$113.55Not available in this settingRVU25D
2025-07-01$113.55Not available in this settingRVU25C
2025-04-01$113.55Not available in this settingRVU25B
2025-01-01$113.55Not available in this settingRVU25A
2024-10-01$119.83Not available in this settingRVU24D
2024-07-01$119.83Not available in this settingRVU24C
2024-04-01$119.83Not available in this settingRVU24B
2024-03-09$119.83Not available in this settingRVU24AR
2024-01-01$117.87Not available in this settingRVU24A
2023-10-01$122.41Not available in this settingRVU23D
2023-07-01$122.41Not available in this settingRVU23C
2023-04-01$122.41Not available in this settingRVU23B
2023-01-01$122.41Not available in this settingRVU23A
2022-10-01$121.32Not available in this settingRVU22D
2022-07-01$121.32Not available in this settingRVU22C
2022-04-01$121.32Not available in this settingRVU22B
2022-01-01$121.32Not available in this settingRVU22A
2021-10-01$122.29Not available in this settingRVU21D
2021-07-01$122.29Not available in this settingRVU21C
2021-04-01$122.29Not available in this settingRVU21B
2021-01-01$122.29Not available in this settingRVU21A
2020-10-01$121.80Not available in this settingRVU20D
2020-07-01$121.80Not available in this settingRVU20C
2020-04-01$121.80Not available in this settingRVU20B
2020-01-01$121.80Not available in this settingRVU20A
2019-10-01$117.59Not available in this settingRVU19D
2019-07-01$117.59Not available in this settingRVU19C
2019-04-01$117.59Not available in this settingRVU19B
2019-01-01$117.59Not available in this settingRVU19A
2018-10-01$115.84Not available in this settingRVU18D
2018-07-01$115.84Not available in this settingRVU18C
2018-04-01$115.84Not available in this settingRVU18B
2018-01-01$115.84Not available in this settingRVU18AR1
2017-10-01$114.02Not available in this settingRVU17D
2017-07-01$114.02Not available in this settingRVU17C
2017-04-01$114.02Not available in this settingRVU17B
2017-01-01$114.02Not available in this settingRVU17A
2016-10-01Rate data unavailableNot available in this settingRVU16D
2016-07-01Rate data unavailableNot available in this settingRVU16C
2016-04-01Rate data unavailableNot available in this settingRVU16B
2016-01-01Rate data unavailableNot available in this settingRVU16A
2015-10-01Rate data unavailableNot available in this settingRVU15D
2015-07-01Rate data unavailableNot available in this settingRVU15C
2015-04-01Rate data unavailableNot available in this settingRVU15B
2015-01-01Rate data unavailableNot available in this settingRVU15A
2014-10-01Rate data unavailableNot available in this settingRVU14D
2014-07-01Rate data unavailableNot available in this settingRVU14C
2014-04-01Rate data unavailableNot available in this settingRVU14B
2014-01-01Rate data unavailableNot available in this settingRVU14A
2013-10-01Rate data unavailableNot available in this settingRVU13D
2013-07-01Rate data unavailableNot available in this settingRVU13C
2013-04-01Rate data unavailableNot available in this settingRVU13B
2013-01-01Rate data unavailableNot available in this settingRVU13AR

Price 88367 for an earlier date of service

Where the Riverside, CA rate applies

Riverside, CA is a Medicare payment area, not a city. Our Census mapping connects it to 127 cities and communities in California. Some span more than one payment area; confirm with the service ZIP.

  • Ontario
  • Riverside
  • San Bernardino
  • Adelanto
  • Aguanga
  • Anza
  • Apple Valley
  • Baker

Browse all communities in California

88367 billing questions

How does this differ from 88368?

88367 represents automated morphometric analysis of in situ hybridization signals. Use 88368 when the morphometric analysis is performed manually.

Is this code for the probe stain itself?

No. It represents automated morphometric analysis of the in situ hybridization signals, rather than the probe stain procedure alone.

When should modifier 26 or TC be used?

Use modifier 26 for the professional interpretation and modifier TC for the technical service, including equipment and staff. Report the global service without either modifier.

What documentation supports reporting 88367?

Document the tissue specimen, in situ hybridization method, automated morphometric analysis performed, and the pathologist’s interpretation.

Is the unit based on the slide or the specimen?

The code is described per specimen. The report should identify the specimen analyzed rather than treating each image or slide as a separate unit automatically.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88367PPRRVU2026_Oct_nonQPP.csv, line 11,294 (RVU26D)
Geographic factors for Riverside, CAGPCI2026.csv, line 20 (RVU26D)

Open CMS sourceHow we calculate rates

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