CPT code 88367: ISH analysis, automated morphometric analysis2026 Medicare rate & RVUs in New Hampshire
Automated morphometric analysis of in situ hybridization signals in tissue helps quantify or assess a molecular finding, such as tumor gene amplification.
In New Hampshire, Medicare pays $108.10 for 88367 in the office.
Check a contract rate as a % of Medicare · 88367 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 88367 covers
This service covers automated morphometric analysis of in situ hybridization signals in a tissue specimen. A pathology laboratory uses imaging equipment and software to assess signal patterns, while a pathologist interprets the findings in the clinical and morphologic context. A familiar application is evaluating HER2 gene amplification in tumor tissue, including breast or gastric specimens, when the assay and analysis method support this code. It represents image-based analysis, not simply the preparation or staining of a probe slide.
Select the code based on the documented analysis method and the applicable CPT distinction between automated and manual analysis. The record should support the specimen analyzed, the in situ hybridization method, the automated analysis performed, and the pathologist’s interpretation. CMS recognizes professional and technical components: report modifier 26 for the interpretation, modifier TC for the equipment and staff, or neither modifier when billing the global service. The CMS fee schedule prices modifiers 26 and TC separately.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How New Hampshire compares for 88367
Across 109 of 109 payment localities, the office rate for 88367 runs from $93.20 in Arkansas to $142.76 in San Benito County, CA. New Hampshire pays $108.10. The RVUs are the same everywhere; the geographic indexes change the dollars.
- New Hampshire · this page$108.10
- Los Angeles, CA · California$120.36+$12.26
- Washington, DC area · District of Columbia$120.56+$12.46
- Miami, FL · Florida$109.20+$1.10
- Chicago, IL · Illinois$106.31−$1.79
- Manhattan, NY · New York$119.83+$11.73
- Alaska · Alaska$121.67+$13.57
Other areas in New Hampshire first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlabamaAlabama | $94.53 | — |
| ArkansasArkansas | $93.20 | — |
| ArizonaArizona | $102.29 | — |
| Bakersfield, CACalifornia | $112.80 | — |
| Chico, CACalifornia | $112.70 | — |
| El Centro, CACalifornia | $112.70 | — |
| Fresno, CACalifornia | $112.70 | — |
| Hanford, CACalifornia | $112.70 | — |
| Madera, CACalifornia | $112.70 | — |
| Merced, CACalifornia | $112.70 | — |
| Modesto, CACalifornia | $112.70 | — |
| Napa, CACalifornia | $131.64 | — |
| Oxnard, CACalifornia | $119.94 | — |
| Redding, CACalifornia | $112.70 | — |
| Rest of CaliforniaCalifornia | $112.70 | — |
| Riverside, CACalifornia | $112.94 | — |
| Sacramento, CACalifornia | $118.54 | — |
| Salinas, CACalifornia | $118.10 | — |
| San Diego, CACalifornia | $121.06 | — |
| Marin County, CACalifornia | $139.77 | — |
| San Francisco, CACalifornia | $139.75 | — |
| San Benito County, CACalifornia | $142.76 | — |
| Santa Clara County, CACalifornia | $142.66 | — |
| San Luis Obispo, CACalifornia | $116.16 | — |
| Santa Cruz, CACalifornia | $122.37 | — |
| Santa Maria, CACalifornia | $118.60 | — |
| Santa Rosa, CACalifornia | $123.63 | — |
| Stockton, CACalifornia | $112.70 | — |
| Vallejo, CACalifornia | $131.61 | — |
| Visalia, CACalifornia | $112.70 | — |
| Yuba City, CACalifornia | $112.70 | — |
| ColoradoColorado | $110.17 | — |
| ConnecticutConnecticut | $111.69 | — |
| DelawareDelaware | $103.96 | — |
| Fort Lauderdale, FLFlorida | $106.47 | — |
| Rest of FloridaFlorida | $101.67 | — |
| Atlanta, GAGeorgia | $106.37 | — |
| Rest of GeorgiaGeorgia | $96.31 | — |
| Hawaii, Guam, HIHawaii | $115.63 | — |
| IowaIowa | $97.63 | — |
| IdahoIdaho | $98.09 | — |
| East St. Louis, ILIllinois | $99.12 | — |
| Rest of IllinoisIllinois | $98.25 | — |
| Suburban Chicago, ILIllinois | $107.73 | — |
| IndianaIndiana | $98.66 | — |
| KansasKansas | $96.82 | — |
| KentuckyKentucky | $95.89 | — |
| New Orleans, LALouisiana | $100.22 | — |
| Rest of LouisianaLouisiana | $95.59 | — |
| Metropolitan Boston, MAMassachusetts | $121.39 | — |
| Rest of MassachusettsMassachusetts | $109.39 | — |
| Baltimore area, MDMaryland | $111.29 | — |
| Rest of MarylandMaryland | $106.03 | — |
| Rest of MaineMaine | $98.19 | — |
| Southern Maine, MEMaine | $103.91 | — |
| Detroit, MIMichigan | $102.52 | — |
| Rest of MichiganMichigan | $97.96 | — |
| MinnesotaMinnesota | $106.74 | — |
| Metropolitan Kansas City, MOMissouri | $99.95 | — |
| Metropolitan St. Louis, MOMissouri | $101.02 | — |
| Rest of MissouriMissouri | $93.75 | — |
| MississippiMississippi | $93.52 | — |
| MontanaMontana | $104.88 | — |
| North CarolinaNorth Carolina | $99.24 | — |
| North DakotaNorth Dakota | $104.48 | — |
| NebraskaNebraska | $98.27 | — |
| Northern New JerseyNew Jersey | $119.30 | — |
| Rest of New JerseyNew Jersey | $113.30 | — |
| New MexicoNew Mexico | $98.33 | — |
| NevadaNevada | $104.85 | — |
| NYC suburbs and Long Island, NYNew York | $122.18 | — |
| Poughkeepsie and northern NYC suburbs, NYNew York | $113.73 | — |
| Queens, NYNew York | $121.34 | — |
| Rest of New YorkNew York | $100.66 | — |
| OhioOhio | $97.88 | — |
| OklahomaOklahoma | $96.12 | — |
| Portland, OROregon | $114.02 | — |
| Rest of OregonOregon | $104.36 | — |
| Metropolitan Philadelphia, PAPennsylvania | $108.73 | — |
| Rest of PennsylvaniaPennsylvania | $98.24 | — |
| Puerto RicoPuerto Rico | $105.75 | — |
| Rhode IslandRhode Island | $107.91 | — |
| South CarolinaSouth Carolina | $98.66 | — |
| South DakotaSouth Dakota | $104.44 | — |
| TennesseeTennessee | $97.24 | — |
| Austin, TXTexas | $109.52 | — |
| Beaumont, TXTexas | $97.59 | — |
| Brazoria, TXTexas | $104.20 | — |
| Dallas, TXTexas | $104.68 | — |
| Fort Worth, TXTexas | $103.88 | — |
| Galveston, TXTexas | $104.39 | — |
| Houston, TXTexas | $104.76 | — |
| Rest of TexasTexas | $100.71 | — |
| UtahUtah | $99.98 | — |
| VirginiaVirginia | $103.31 | — |
| Virgin Islands, VIUnited States Virgin Islands | $105.75 | — |
| VermontVermont | $103.74 | — |
| Rest of WashingtonWashington | $109.29 | — |
| King County, WAWashington | $124.21 | — |
| WisconsinWisconsin | $101.04 | — |
| West VirginiaWest Virginia | $94.62 | — |
| WyomingWyoming | $104.71 | — |
88367 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$93.20
$127.73
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $121.67 | 1 |
| AL | $94.53 | 1 |
| AR | $93.20 | 1 |
| AZ | $102.29 | 1 |
| CA | $112.70–$142.76 | 29 |
| CO | $110.17 | 1 |
| CT | $111.69 | 1 |
| DC | $120.56 | 1 |
| DE | $103.96 | 1 |
| FL | $101.67–$109.20 | 3 |
| GA | $96.31–$106.37 | 2 |
| GU | $115.63 | 1 |
| HI | $115.63 | 1 |
| IA | $97.63 | 1 |
| ID | $98.09 | 1 |
| IL | $98.25–$107.73 | 4 |
| IN | $98.66 | 1 |
| KS | $96.82 | 1 |
| KY | $95.89 | 1 |
| LA | $95.59–$100.22 | 2 |
| MA | $109.39–$121.39 | 2 |
| MD | $106.03–$120.56 | 3 |
| ME | $98.19–$103.91 | 2 |
| MI | $97.96–$102.52 | 2 |
| MN | $106.74 | 1 |
| MO | $93.75–$101.02 | 3 |
| MS | $93.52 | 1 |
| MT | $104.88 | 1 |
| NC | $99.24 | 1 |
| ND | $104.48 | 1 |
| NE | $98.27 | 1 |
| NH | $108.10 | 1 |
| NJ | $113.30–$119.30 | 2 |
| NM | $98.33 | 1 |
| NV | $104.85 | 1 |
| NY | $100.66–$122.18 | 5 |
| OH | $97.88 | 1 |
| OK | $96.12 | 1 |
| OR | $104.36–$114.02 | 2 |
| PA | $98.24–$108.73 | 2 |
| PR | $105.75 | 1 |
| RI | $107.91 | 1 |
| SC | $98.66 | 1 |
| SD | $104.44 | 1 |
| TN | $97.24 | 1 |
| TX | $97.59–$109.52 | 8 |
| UT | $99.98 | 1 |
| VA | $103.31–$120.56 | 2 |
| VI | $105.75 | 1 |
| VT | $103.74 | 1 |
| WA | $109.29–$124.21 | 2 |
| WI | $101.04 | 1 |
| WV | $94.62 | 1 |
| WY | $104.71 | 1 |
How the 88367 rate is calculated
Each of 88367’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 88367
RVUs × geographic indexes × conversion factor
Work0.71
0.71 RVUs× 1.000 GPCI
Practice expense2.41
2.41 RVUs× 1.000 GPCI
Malpractice0.02
0.02 RVUs× 1.000 GPCI
Adjusted RVUs
3.1400
Conversion factor
$33.4009
Medicare rate
$104.88
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact New Hampshire inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
11,294
- Code
- 88367
- Physician work
- 0.71
- Practice expense
- 2.41
- Malpractice
- 0.02
GPCI2026.csv
74
- Locality
- New Hampshire
- Physician work
- 1.000
- Practice expense
- 1.041
- Malpractice
- 0.875
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.71 | × 1.000 | 0.7100 |
| Practice expense | 2.41 | × 1.041 | 2.5088 |
| Malpractice | 0.02 | × 0.875 | 0.0175 |
| Total RVUs | 3.2363 | ||
| Conversion factor | × 33.4009 | ||
Office rate, New Hampshire$108.10
Office: (0.71 × 1 + 2.41 × 1.041 + 0.02 × 0.875) × $33.4009 = $108.10
Payment rules and modifiers for 88367
The CMS indicators that decide how 88367 is paid alongside other services.
CMS payment indicators · 88367
ISH analysis, automated morphometric analysis
| Rule | CMS value | What it means |
|---|---|---|
| Global period | XXX | The global surgery concept doesn’t apply. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 1 | Diagnostic test with separate professional (26) and technical (TC) components. |
What modifiers do to the payment
Modifier 26 · payment effect
With and without the modifier
88367 without 26 · national office
$104.88
ISH analysis, automated morphometric analysis
88367-26 · Professional component
$31.06
Pays only the interpretation and report.
How 88367 has changed in New Hampshire
88367 · Office / nonfacility
$108.10
Effective 2026-10-01
The base rate is $0.33 lower than on 2025-10-01, moving from $108.43 to $108.10 (0.3%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$108.43changed to$108.10
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 0.73 changed to 0.71
- Practice expense RVU 2.51 changed to 2.41
- Malpractice RVU 0.03 changed to 0.02
- Practice expense GPCI 1.034 changed to 1.041
- Malpractice GPCI 0.898 changed to 0.875
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
$114.39changed to$108.43
- Conversion factor 33.2875 changed to 32.3465
- Practice expense RVU 2.60 changed to 2.51
- Malpractice RVU 0.02 changed to 0.03
Held through RVU25B, RVU25C, RVU25D.
March 9, 2024
RVU24AR
$112.52changed to$114.39
- Conversion factor 32.7442 changed to 33.2875
Held through RVU24B, RVU24C, RVU24D.
January 1, 2024
RVU24A
$118.04changed to$112.52
- Conversion factor 33.8872 changed to 32.7442
- Practice expense RVU 2.64 changed to 2.60
- Practice expense GPCI 1.036 changed to 1.034
- Malpractice GPCI 0.907 changed to 0.898
January 1, 2023
RVU23A
$118.21changed to$118.04
- Conversion factor 34.6062 changed to 33.8872
- Practice expense RVU 2.57 changed to 2.64
- Practice expense GPCI 1.038 changed to 1.036
- Malpractice GPCI 0.917 changed to 0.907
Held through RVU23B, RVU23C, RVU23D.
January 1, 2022
RVU22A
$119.19changed to$118.21
- Conversion factor 34.8931 changed to 34.6062
Held through RVU22B, RVU22C, RVU22D.
January 1, 2021
RVU21A
$118.81changed to$119.19
- Conversion factor 36.0896 changed to 34.8931
- Practice expense RVU 2.44 changed to 2.57
- Practice expense GPCI 1.042 changed to 1.038
- Malpractice GPCI 0.984 changed to 0.917
Held through RVU21B, RVU21C, RVU21D.
January 1, 2020
RVU20A
$114.82changed to$118.81
- Conversion factor 36.0391 changed to 36.0896
- Practice expense RVU 2.33 changed to 2.44
- Practice expense GPCI 1.045 changed to 1.042
- Malpractice GPCI 1.050 changed to 0.984
Held through RVU20B, RVU20C, RVU20D.
January 1, 2019
RVU19A
$113.18changed to$114.82
- Conversion factor 35.9996 changed to 36.0391
- Practice expense RVU 2.29 changed to 2.33
Held through RVU19B, RVU19C, RVU19D.
January 1, 2018
RVU18AR1
$111.46changed to$113.18
- Conversion factor 35.8887 changed to 35.9996
- Practice expense RVU 2.24 changed to 2.29
- Practice expense GPCI 1.052 changed to 1.045
- Malpractice GPCI 0.962 changed to 1.050
Held through RVU18B, RVU18C, RVU18D.
January 1, 2017
RVU17A
$111.62changed to$111.46
- Conversion factor 35.8043 changed to 35.8887
- Practice expense GPCI 1.058 changed to 1.052
- Malpractice GPCI 0.873 changed to 0.962
Held through RVU17B, RVU17C, RVU17D.
January 1, 2016
RVU16A
$112.40changed to$111.62
- Conversion factor 35.9335 changed to 35.8043
- Practice expense RVU 2.25 changed to 2.24
Held through RVU16B, RVU16C, RVU16D.
July 1, 2015
RVU15C
$111.84changed to$112.40
- Conversion factor 35.7547 changed to 35.9335
Held through RVU15D.
January 1, 2015
RVU15A
$266.05changed to$111.84
- Conversion factor 35.8228 changed to 35.7547
- Work RVU 1.30 changed to 0.73
- Practice expense RVU 5.78 changed to 2.25
- Malpractice RVU 0.06 changed to 0.02
- Practice expense GPCI 1.051 changed to 1.058
- Malpractice GPCI 0.867 changed to 0.873
Held through RVU15B.
January 1, 2014
RVU14A
No ratechanged to$266.05
Held through RVU14B, RVU14C, RVU14D.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $108.10 | Not available in this setting | RVU26D |
| 2026-07-01 | $108.10 | Not available in this setting | RVU26C |
| 2026-04-01 | $108.10 | Not available in this setting | RVU26B |
| 2026-01-01 | $108.10 | Not available in this setting | RVU26A |
| 2025-10-01 | $108.43 | Not available in this setting | RVU25D |
| 2025-07-01 | $108.43 | Not available in this setting | RVU25C |
| 2025-04-01 | $108.43 | Not available in this setting | RVU25B |
| 2025-01-01 | $108.43 | Not available in this setting | RVU25A |
| 2024-10-01 | $114.39 | Not available in this setting | RVU24D |
| 2024-07-01 | $114.39 | Not available in this setting | RVU24C |
| 2024-04-01 | $114.39 | Not available in this setting | RVU24B |
| 2024-03-09 | $114.39 | Not available in this setting | RVU24AR |
| 2024-01-01 | $112.52 | Not available in this setting | RVU24A |
| 2023-10-01 | $118.04 | Not available in this setting | RVU23D |
| 2023-07-01 | $118.04 | Not available in this setting | RVU23C |
| 2023-04-01 | $118.04 | Not available in this setting | RVU23B |
| 2023-01-01 | $118.04 | Not available in this setting | RVU23A |
| 2022-10-01 | $118.21 | Not available in this setting | RVU22D |
| 2022-07-01 | $118.21 | Not available in this setting | RVU22C |
| 2022-04-01 | $118.21 | Not available in this setting | RVU22B |
| 2022-01-01 | $118.21 | Not available in this setting | RVU22A |
| 2021-10-01 | $119.19 | Not available in this setting | RVU21D |
| 2021-07-01 | $119.19 | Not available in this setting | RVU21C |
| 2021-04-01 | $119.19 | Not available in this setting | RVU21B |
| 2021-01-01 | $119.19 | Not available in this setting | RVU21A |
| 2020-10-01 | $118.81 | Not available in this setting | RVU20D |
| 2020-07-01 | $118.81 | Not available in this setting | RVU20C |
| 2020-04-01 | $118.81 | Not available in this setting | RVU20B |
| 2020-01-01 | $118.81 | Not available in this setting | RVU20A |
| 2019-10-01 | $114.82 | Not available in this setting | RVU19D |
| 2019-07-01 | $114.82 | Not available in this setting | RVU19C |
| 2019-04-01 | $114.82 | Not available in this setting | RVU19B |
| 2019-01-01 | $114.82 | Not available in this setting | RVU19A |
| 2018-10-01 | $113.18 | Not available in this setting | RVU18D |
| 2018-07-01 | $113.18 | Not available in this setting | RVU18C |
| 2018-04-01 | $113.18 | Not available in this setting | RVU18B |
| 2018-01-01 | $113.18 | Not available in this setting | RVU18AR1 |
| 2017-10-01 | $111.46 | Not available in this setting | RVU17D |
| 2017-07-01 | $111.46 | Not available in this setting | RVU17C |
| 2017-04-01 | $111.46 | Not available in this setting | RVU17B |
| 2017-01-01 | $111.46 | Not available in this setting | RVU17A |
| 2016-10-01 | $111.62 | Not available in this setting | RVU16D |
| 2016-07-01 | $111.62 | Not available in this setting | RVU16C |
| 2016-04-01 | $111.62 | Not available in this setting | RVU16B |
| 2016-01-01 | $111.62 | Not available in this setting | RVU16A |
| 2015-10-01 | $112.40 | Not available in this setting | RVU15D |
| 2015-07-01 | $112.40 | Not available in this setting | RVU15C |
| 2015-04-01 | $111.84 | Not available in this setting | RVU15B |
| 2015-01-01 | $111.84 | Not available in this setting | RVU15A |
| 2014-10-01 | $266.05 | Not available in this setting | RVU14D |
| 2014-07-01 | $266.05 | Not available in this setting | RVU14C |
| 2014-04-01 | $266.05 | Not available in this setting | RVU14B |
| 2014-01-01 | $266.05 | Not available in this setting | RVU14A |
| 2013-10-01 | Rate data unavailable | Not available in this setting | RVU13D |
| 2013-07-01 | Rate data unavailable | Not available in this setting | RVU13C |
| 2013-04-01 | Rate data unavailable | Not available in this setting | RVU13B |
| 2013-01-01 | Rate data unavailable | Not available in this setting | RVU13AR |
Where the New Hampshire rate applies
New Hampshire is a Medicare payment area, not a city. Our Census mapping connects it to 100 cities and communities in New Hampshire. Some span more than one payment area; confirm with the service ZIP.
- Alton
- Amherst
- Antrim
- Ashland
- Bartlett
- Belmont
- Bennington
- Berlin
88367 billing questions
How does this differ from 88368?
88367 represents automated morphometric analysis of in situ hybridization signals. Use 88368 when the morphometric analysis is performed manually.
Is this code for the probe stain itself?
No. It represents automated morphometric analysis of the in situ hybridization signals, rather than the probe stain procedure alone.
When should modifier 26 or TC be used?
Use modifier 26 for the professional interpretation and modifier TC for the technical service, including equipment and staff. Report the global service without either modifier.
What documentation supports reporting 88367?
Document the tissue specimen, in situ hybridization method, automated morphometric analysis performed, and the pathologist’s interpretation.
Is the unit based on the slide or the specimen?
The code is described per specimen. The report should identify the specimen analyzed rather than treating each image or slide as a separate unit automatically.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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