CPT code 96450: Chemotherapy administration, into central nervous system2026 Medicare rate & RVUs in Kentucky

In Kentucky, Medicare pays $148.92 for 96450 in the office and $64.88 when it’s performed in a hospital or facility.

Check a contract rate as a % of Medicare · 96450 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 96450 covers

This service covers delivery of chemotherapy into the central nervous system, most commonly by an intrathecal route through a lumbar puncture. It may be performed in an oncology or hematology clinic, hospital outpatient department, or other setting where CNS-directed treatment is administered. Patients may receive it for conditions such as CNS leukemia or leptomeningeal disease. Administration through an intraventricular access device is also a CNS route.

Select this code based on the route of drug delivery, not the drug name or the diagnosis alone. Documentation should identify the medication, CNS route, access method, and completed administration. The spinal puncture used to access the treatment site is included in this service. The chemotherapy drug itself is separate from the administration service when separately reportable. CMS assigns a 0-day global period, so same-day preoperative and postoperative care is included. Modifier 50 is inappropriate. Assistant-at-surgery payment requires medical-necessity documentation; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Kentucky compares for 96450

Across 109 of 109 payment localities, the office rate for 96450 runs from $143.89 in Arkansas to $210.95 in San Benito County, CA. Kentucky pays $148.92. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

96450 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 96450 in every payment locality

How the 96450 rate is calculated

Each of 96450’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 96450

The CMS indicators that decide how 96450 is paid alongside other services.

Codes related to 96450

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 96450 has changed in Kentucky

Price 96450 for an earlier date of service

Where the Kentucky rate applies

Kentucky is a Medicare payment area, not a city. Our Census mapping connects it to 553 cities and communities in Kentucky. Some span more than one payment area; confirm with the service ZIP.

• Adairville
• Ages
• Albany
• Alexandria
• Allen
• Allensville
• Anchorage
• Annville

Browse all communities in Kentucky

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates