HCPCS code G0452: Molecular interpretation, physician interpretation and report2026 Medicare rate & RVUs in Riverside, CA

Reports a physician’s interpretation of molecular pathology test results, separately from or as part of the global diagnostic service.

CMS RVU26DEffective Oct 1, 2026One payment locality163.3K Medicare services in 2024

In Riverside, CA, Medicare pays $48.72 for G0452 in the office.

$48.72Office (non-facility)
Not available in this settingHospital or facility
+4.2%vs the national office rate ($46.76)

Check a contract rate as a % of Medicare · G0452 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open G0452 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Riverside, CA
  2. What G0452 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What G0452 covers

A physician reviews results from a molecular pathology assay and prepares an interpretation and report. The testing may analyze DNA or RNA from sources such as tumor tissue or blood to identify molecular findings relevant to diagnosis or treatment. A pathologist or another qualified physician may provide this service in a hospital, reference laboratory, or other setting where molecular diagnostic testing is performed.

Report G0452 for the physician’s interpretive service when supported by the work documented; the assay itself is represented by its applicable test code. CMS recognizes professional and technical components: modifier 26 identifies the interpretation, and modifier TC identifies the technical work, including equipment and staff. Without either modifier, the claim represents the global service. Documentation should identify the test results reviewed and include the physician’s interpretive findings and report. CMS lists modifiers 26 and TC as separately priced.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Riverside, CA compares for G0452

Across 109 of 109 payment localities, the office rate for G0452 runs from $44.22 in Arkansas to $62.68 in Alaska. Riverside, CA pays $48.72. The RVUs are the same everywhere; the geographic indexes change the dollars.

G0452 in Riverside, CA vs other payment areas
  1. Riverside, CA · this page$48.72
  2. Bakersfield, CA · California$48.58−$0.14
  3. Chico, CA · California$48.48−$0.24
  4. El Centro, CA · California$48.48−$0.24
  5. Fresno, CA · California$48.48−$0.24
  6. Hanford, CA · California$48.48−$0.24
  7. Los Angeles, CA · California$50.66+$1.94

Other areas in California first, then benchmark localities. Bars start at $0.

Every other payment area

G0452 in every other Medicare payment locality
Payment localityOfficeFacility
Madera, CACalifornia$48.48—
Merced, CACalifornia$48.48—
Modesto, CACalifornia$48.48—
Napa, CACalifornia$53.34—
Oxnard, CACalifornia$50.22—
Redding, CACalifornia$48.48—
Rest of CaliforniaCalifornia$48.48—
Sacramento, CACalifornia$50.10—

G0452 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$44.22

$62.68

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
G0452 office rate range by state
State / territoryOffice rate rangeLocalities
AK$62.681
AL$44.511
AR$44.221
AZ$46.181
CA$48.48–$56.7329
CO$47.981
CT$48.721
DC$51.271
DE$46.661
FL$46.41–$48.433
GA$45.19–$47.242
GU$48.631
HI$48.631
IA$45.021
ID$45.151
IL$45.77–$47.924
IN$45.271
KS$44.921
KY$44.961
LA$44.93–$45.932
MA$47.94–$50.982
MD$47.20–$51.273
ME$45.25–$46.372
MI$45.48–$46.672
MN$46.751
MO$44.58–$46.013
MS$44.401
MT$46.761
NC$45.471
ND$46.361
NE$45.141
NH$47.321
NJ$49.49–$51.232
NM$45.591
NV$46.671
NY$45.78–$52.255
OH$45.401
OK$44.931
OR$46.50–$48.822
PA$45.44–$48.082
PR$46.921
RI$47.781
SC$45.471
SD$46.321
TN$45.021
TX$45.30–$47.668
UT$45.751
VA$46.30–$51.272
VI$46.921
VT$46.271
WA$47.83–$51.722
WI$45.641
WV$44.991
WY$46.591

See G0452 in every payment locality

How the G0452 rate is calculated

Each of G0452’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · G0452

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.91

0.91 RVUs× 1.000 GPCI

Practice expense0.47

0.47 RVUs× 1.000 GPCI

Malpractice0.02

0.02 RVUs× 1.000 GPCI

Adjusted RVUs

1.4000

Conversion factor

$33.4009

Medicare rate

$46.76

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Riverside, CA inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

15,270

Code
G0452
Physician work
0.91
Practice expense
0.47
Malpractice
0.02

GPCI2026.csv

20

Locality
Riverside, CA
Physician work
1.018
Practice expense
1.096
Malpractice
0.853
Office calculation for G0452 in Riverside, CA
ComponentRVULocality factorAdjusted
Physician work0.91× 1.0180.9264
Practice expense0.47× 1.0960.5151
Malpractice0.02× 0.8530.0171
Total RVUs1.4586
Conversion factor× 33.4009

Office rate, Riverside, CA$48.72

Office: (0.91 × 1.018 + 0.47 × 1.096 + 0.02 × 0.853) × $33.4009 = $48.72

Open G0452 in the RVU calculator

Payment rules and modifiers for G0452

The CMS indicators that decide how G0452 is paid alongside other services.

CMS payment indicators · G0452

Molecular interpretation, physician interpretation and report

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical1Diagnostic test with separate professional (26) and technical (TC) components.

What modifiers do to the payment

Modifier 26 · payment effect

With and without the modifier

G0452 without 26 · national office

$46.76

Molecular interpretation, physician interpretation and report

G0452-26 · Professional component

$43.76

Pays only the interpretation and report.

When to use modifier 26

How G0452 has changed in Riverside, CA

G0452 · Office / nonfacility

$48.72

Effective 2026-10-01

The base rate is $0.39 lower than on 2025-10-01, moving from $49.11 to $48.72 (0.8%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $49.11changed to$48.72

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.93 changed to 0.91
    • Practice expense RVU 0.51 changed to 0.47
    • Work GPCI 1.014 changed to 1.018
    • Practice expense GPCI 1.093 changed to 1.096
    • Malpractice GPCI 0.892 changed to 0.853

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $50.84changed to$49.11

    • Conversion factor 33.2875 changed to 32.3465
    • Malpractice RVU 0.03 changed to 0.02

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $50.01changed to$50.84

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $51.76changed to$50.01

    • Conversion factor 33.8872 changed to 32.7442
    • Work GPCI 1.021 changed to 1.014
    • Practice expense GPCI 1.079 changed to 1.093
    • Malpractice GPCI 0.924 changed to 0.892
  5. January 1, 2023

    RVU23A

    $50.92changed to$51.76

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.44 changed to 0.51
    • Malpractice RVU 0.05 changed to 0.03
    • Work GPCI 1.027 changed to 1.021
    • Practice expense GPCI 1.065 changed to 1.079
    • Malpractice GPCI 0.955 changed to 0.924

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $51.24changed to$50.92

    • Conversion factor 34.8931 changed to 34.6062
    • Malpractice GPCI 0.896 changed to 0.955

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    No ratechanged to$51.24

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$48.72Not available in this settingRVU26D
2026-07-01$48.72Not available in this settingRVU26C
2026-04-01$48.72Not available in this settingRVU26B
2026-01-01$48.72Not available in this settingRVU26A
2025-10-01$49.11Not available in this settingRVU25D
2025-07-01$49.11Not available in this settingRVU25C
2025-04-01$49.11Not available in this settingRVU25B
2025-01-01$49.11Not available in this settingRVU25A
2024-10-01$50.84Not available in this settingRVU24D
2024-07-01$50.84Not available in this settingRVU24C
2024-04-01$50.84Not available in this settingRVU24B
2024-03-09$50.84Not available in this settingRVU24AR
2024-01-01$50.01Not available in this settingRVU24A
2023-10-01$51.76Not available in this settingRVU23D
2023-07-01$51.76Not available in this settingRVU23C
2023-04-01$51.76Not available in this settingRVU23B
2023-01-01$51.76Not available in this settingRVU23A
2022-10-01$50.92Not available in this settingRVU22D
2022-07-01$50.92Not available in this settingRVU22C
2022-04-01$50.92Not available in this settingRVU22B
2022-01-01$50.92Not available in this settingRVU22A
2021-10-01$51.24Not available in this settingRVU21D
2021-07-01$51.24Not available in this settingRVU21C
2021-04-01$51.24Not available in this settingRVU21B
2021-01-01$51.24Not available in this settingRVU21A
2020-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU20D
2020-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU20C
2020-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU20B
2020-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU20A
2019-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU19D
2019-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU19C
2019-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU19B
2019-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU19A
2018-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU18D
2018-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU18C
2018-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU18B
2018-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU18AR1
2017-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU17D
2017-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU17C
2017-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU17B
2017-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU17A
2016-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU16D
2016-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU16C
2016-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU16B
2016-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU16A
2015-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU15D
2015-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU15C
2015-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU15B
2015-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU15A
2014-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU14D
2014-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU14C
2014-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU14B
2014-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU14A
2013-10-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU13D
2013-07-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU13C
2013-04-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU13B
2013-01-01No unmodified rate in this releaseNo unmodified rate in this releaseRVU13AR

Price G0452 for an earlier date of service

Where the Riverside, CA rate applies

Riverside, CA is a Medicare payment area, not a city. Our Census mapping connects it to 127 cities and communities in California. Some span more than one payment area; confirm with the service ZIP.

  • Ontario
  • Riverside
  • San Bernardino
  • Adelanto
  • Aguanga
  • Anza
  • Apple Valley
  • Baker

Browse all communities in California

G0452 billing questions

When should G0452 be reported instead of the molecular assay code?

G0452 represents the physician’s interpretation and report, not the laboratory procedure that generates the molecular results. Report the applicable assay code for the testing itself.

How do modifiers 26 and TC affect G0452?

Modifier 26 reports the professional interpretation, while modifier TC reports the technical work, including equipment and staff. Without a modifier, G0452 represents the global service.

What documentation supports G0452?

Document the molecular test results reviewed and the physician’s interpretation and report. The record should make clear that the reported service includes interpretive work, not only test performance.

Can G0452 be reported with a molecular assay code?

Yes, the interpretation may be reported with the applicable molecular assay code when both the test and the physician’s interpretive service are furnished and documented.

Does G0452 describe a particular gene panel or specimen?

No. G0452 identifies the interpretation and report service; the assay code identifies the specific molecular test and its scope.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for G0452PPRRVU2026_Oct_nonQPP.csv, line 15,270 (RVU26D)
Geographic factors for Riverside, CAGPCI2026.csv, line 20 (RVU26D)

Open CMS sourceHow we calculate rates

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