HCPCS code Q4315: Amniotic allograft, regenelink product2026 Medicare rate & RVUs in Puerto Rico
Report Q4315 for Regenelink amniotic membrane allograft used with a primary wound-treatment procedure, with units supported by the amount applied.
In Puerto Rico, Medicare pays $128.66 for Q4315 in the office.
Check a contract rate as a % of Medicare · Q4315 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What Q4315 covers
Q4315 identifies the Regenelink amniotic membrane allograft supplied for wound treatment. The graft is placed over a prepared wound as a covering or adjunct to wound care. Wound-care clinicians, podiatrists, and surgeons may use amniotic membrane products in outpatient settings for wounds such as diabetic foot ulcers or venous leg ulcers; the specific product documented must be Regenelink for this code to apply.
Report Q4315 with the primary procedure for the graft application; CMS classifies it as an add-on code paid within that procedure’s global period. The record should identify the product, wound site, application procedure, and amount applied, with units reflecting the product’s per-square-centimeter billing basis. CMS classifies this code as technical-component-only, with interpretation covered by a separate code. The Q4315 line represents the product’s technical portion, not interpretation.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Puerto Rico compares for Q4315
Across 109 of 109 payment localities, the office rate for Q4315 runs from $109.31 in Arkansas to $183.51 in Santa Clara County, CA. Puerto Rico pays $128.66. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Puerto Rico · this page$128.66
- Los Angeles, CA · California$150.55+$21.89
- Washington, DC area · District of Columbia$149.91+$21.25
- Miami, FL · Florida$132.47+$3.81
- Chicago, IL · Illinois$127.89−$0.77
- Manhattan, NY · New York$147.87+$19.21
- Alaska · Alaska$135.53+$6.87
Other areas in Puerto Rico first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlabamaAlabama | $111.35 | — |
| ArkansasArkansas | $109.31 | — |
| ArizonaArizona | $123.31 | — |
| Bakersfield, CACalifornia | $139.47 | — |
| Chico, CACalifornia | $139.47 | — |
| El Centro, CACalifornia | $139.47 | — |
| Fresno, CACalifornia | $139.47 | — |
| Hanford, CACalifornia | $139.47 | — |
| Madera, CACalifornia | $139.47 | — |
| Merced, CACalifornia | $139.47 | — |
| Modesto, CACalifornia | $139.47 | — |
| Napa, CACalifornia | $167.73 | — |
| Oxnard, CACalifornia | $150.42 | — |
| Redding, CACalifornia | $139.47 | — |
| Rest of CaliforniaCalifornia | $139.47 | — |
| Riverside, CACalifornia | $139.47 | — |
| Sacramento, CACalifornia | $148.00 | — |
| Salinas, CACalifornia | $147.49 | — |
| San Diego, CACalifornia | $152.20 | — |
| Marin County, CACalifornia | $179.43 | — |
| San Francisco, CACalifornia | $179.43 | — |
| San Benito County, CACalifornia | $183.51 | — |
| Santa Clara County, CACalifornia | $183.51 | — |
| San Luis Obispo, CACalifornia | $144.95 | — |
| Santa Cruz, CACalifornia | $154.62 | — |
| Santa Maria, CACalifornia | $148.38 | — |
| Santa Rosa, CACalifornia | $156.27 | — |
| Stockton, CACalifornia | $139.47 | — |
| Vallejo, CACalifornia | $167.73 | — |
| Visalia, CACalifornia | $139.47 | — |
| Yuba City, CACalifornia | $139.47 | — |
| ColoradoColorado | $135.40 | — |
| ConnecticutConnecticut | $137.06 | — |
| DelawareDelaware | $125.73 | — |
| Fort Lauderdale, FLFlorida | $128.91 | — |
| Rest of FloridaFlorida | $121.66 | — |
| Atlanta, GAGeorgia | $129.29 | — |
| Rest of GeorgiaGeorgia | $113.51 | — |
| Hawaii, Guam, HIHawaii | $144.69 | — |
| IowaIowa | $116.44 | — |
| IdahoIdaho | $117.08 | — |
| East St. Louis, ILIllinois | $117.08 | — |
| Rest of IllinoisIllinois | $116.19 | — |
| Suburban Chicago, ILIllinois | $130.69 | — |
| IndianaIndiana | $117.97 | — |
| KansasKansas | $115.04 | — |
| KentuckyKentucky | $113.13 | — |
| New Orleans, LALouisiana | $119.75 | — |
| Rest of LouisianaLouisiana | $112.62 | — |
| Metropolitan Boston, MAMassachusetts | $151.95 | — |
| Rest of MassachusettsMassachusetts | $134.00 | — |
| Baltimore area, MDMaryland | $136.55 | — |
| Rest of MarylandMaryland | $128.78 | — |
| Rest of MaineMaine | $117.08 | — |
| Southern Maine, MEMaine | $126.11 | — |
| Detroit, MIMichigan | $122.80 | — |
| Rest of MichiganMichigan | $116.19 | — |
| MinnesotaMinnesota | $130.95 | — |
| Metropolitan Kansas City, MOMissouri | $119.49 | — |
| Metropolitan St. Louis, MOMissouri | $121.15 | — |
| Rest of MissouriMissouri | $109.70 | — |
| MississippiMississippi | $109.57 | — |
| MontanaMontana | $127.26 | — |
| North CarolinaNorth Carolina | $118.73 | — |
| North DakotaNorth Dakota | $127.26 | — |
| NebraskaNebraska | $117.46 | — |
| New HampshireNew Hampshire | $132.47 | — |
| Northern New JerseyNew Jersey | $147.62 | — |
| Rest of New JerseyNew Jersey | $138.97 | — |
| New MexicoNew Mexico | $116.70 | — |
| NevadaNevada | $127.38 | — |
| NYC suburbs and Long Island, NYNew York | $151.31 | — |
| Poughkeepsie and northern NYC suburbs, NYNew York | $139.35 | — |
| Queens, NYNew York | $150.42 | — |
| Rest of New YorkNew York | $120.89 | — |
| OhioOhio | $116.19 | — |
| OklahomaOklahoma | $113.64 | — |
| Portland, OROregon | $141.38 | — |
| Rest of OregonOregon | $126.75 | — |
| Metropolitan Philadelphia, PAPennsylvania | $132.47 | — |
| Rest of PennsylvaniaPennsylvania | $116.82 | — |
| Rhode IslandRhode Island | $131.46 | — |
| South CarolinaSouth Carolina | $117.59 | — |
| South DakotaSouth Dakota | $127.26 | — |
| TennesseeTennessee | $115.68 | — |
| Austin, TXTexas | $134.64 | — |
| Beaumont, TXTexas | $115.80 | — |
| Brazoria, TXTexas | $126.11 | — |
| Dallas, TXTexas | $126.75 | — |
| Fort Worth, TXTexas | $125.48 | — |
| Galveston, TXTexas | $126.37 | — |
| Houston, TXTexas | $126.37 | — |
| Rest of TexasTexas | $120.77 | — |
| UtahUtah | $119.62 | — |
| VirginiaVirginia | $125.09 | — |
| Virgin Islands, VIUnited States Virgin Islands | $128.66 | — |
| VermontVermont | $125.98 | — |
| Rest of WashingtonWashington | $134.00 | — |
| King County, WAWashington | $156.14 | — |
| WisconsinWisconsin | $121.91 | — |
| West VirginiaWest Virginia | $110.59 | — |
| WyomingWyoming | $127.26 | — |
Q4315 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$109.31
$161.49
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $135.53 | 1 |
| AL | $111.35 | 1 |
| AR | $109.31 | 1 |
| AZ | $123.31 | 1 |
| CA | $139.47–$183.51 | 29 |
| CO | $135.40 | 1 |
| CT | $137.06 | 1 |
| DC | $149.91 | 1 |
| DE | $125.73 | 1 |
| FL | $121.66–$132.47 | 3 |
| GA | $113.51–$129.29 | 2 |
| GU | $144.69 | 1 |
| HI | $144.69 | 1 |
| IA | $116.44 | 1 |
| ID | $117.08 | 1 |
| IL | $116.19–$130.69 | 4 |
| IN | $117.97 | 1 |
| KS | $115.04 | 1 |
| KY | $113.13 | 1 |
| LA | $112.62–$119.75 | 2 |
| MA | $134.00–$151.95 | 2 |
| MD | $128.78–$149.91 | 3 |
| ME | $117.08–$126.11 | 2 |
| MI | $116.19–$122.80 | 2 |
| MN | $130.95 | 1 |
| MO | $109.70–$121.15 | 3 |
| MS | $109.57 | 1 |
| MT | $127.26 | 1 |
| NC | $118.73 | 1 |
| ND | $127.26 | 1 |
| NE | $117.46 | 1 |
| NH | $132.47 | 1 |
| NJ | $138.97–$147.62 | 2 |
| NM | $116.70 | 1 |
| NV | $127.38 | 1 |
| NY | $120.89–$151.31 | 5 |
| OH | $116.19 | 1 |
| OK | $113.64 | 1 |
| OR | $126.75–$141.38 | 2 |
| PA | $116.82–$132.47 | 2 |
| PR | $128.66 | 1 |
| RI | $131.46 | 1 |
| SC | $117.59 | 1 |
| SD | $127.26 | 1 |
| TN | $115.68 | 1 |
| TX | $115.80–$134.64 | 8 |
| UT | $119.62 | 1 |
| VA | $125.09–$149.91 | 2 |
| VI | $128.66 | 1 |
| VT | $125.98 | 1 |
| WA | $134.00–$156.14 | 2 |
| WI | $121.91 | 1 |
| WV | $110.59 | 1 |
| WY | $127.26 | 1 |
How the Q4315 rate is calculated
Each of Q4315’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · Q4315
RVUs × geographic indexes × conversion factor
Work0.00
0.00 RVUs× 1.000 GPCI
Practice expense3.81
3.81 RVUs× 1.000 GPCI
Malpractice0.00
0.00 RVUs× 1.000 GPCI
Adjusted RVUs
3.8100
Conversion factor
$33.4009
Medicare rate
$127.26
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Puerto Rico inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
18,402
- Code
- Q4315
- Physician work
- 0.00
- Practice expense
- 3.81
- Malpractice
- 0.00
GPCI2026.csv
91
- Locality
- Puerto Rico
- Physician work
- 1.000
- Practice expense
- 1.011
- Malpractice
- 0.985
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.00 | × 1.000 | 0.0000 |
| Practice expense | 3.81 | × 1.011 | 3.8519 |
| Malpractice | 0.00 | × 0.985 | 0.0000 |
| Total RVUs | 3.8519 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Puerto Rico$128.66
Office: (0 × 1 + 3.81 × 1.011 + 0 × 0.985) × $33.4009 = $128.66
Payment rules and modifiers for Q4315
The CMS indicators that decide how Q4315 is paid alongside other services.
CMS payment indicators · Q4315
Amniotic allograft, regenelink product
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 3 | Technical component only. |
How Q4315 has changed in Puerto Rico
Q4315 · Office / nonfacility
$128.66
Effective 2026-10-01
A rate is unavailable in one of these releases, so a change cannot be calculated.
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
No ratechanged to$128.66
Held through RVU26B, RVU26C, RVU26D.
July 1, 2024
RVU24C
No ratechanged toNo rate
Held through RVU24D, RVU25A, RVU25B, RVU25C, RVU25D.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D, RVU14A, RVU14B, RVU14C, RVU14D, RVU15A, RVU15B, RVU15C, RVU15D, RVU16A, RVU16B, RVU16C, RVU16D, RVU17A, RVU17B, RVU17C, RVU17D, RVU18AR1, RVU18B, RVU18C, RVU18D, RVU19A, RVU19B, RVU19C, RVU19D, RVU20A, RVU20B, RVU20C, RVU20D, RVU21A, RVU21B, RVU21C, RVU21D, RVU22A, RVU22B, RVU22C, RVU22D, RVU23A, RVU23B, RVU23C, RVU23D, RVU24A, RVU24AR, RVU24B.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $128.66 | Not available in this setting | RVU26D |
| 2026-07-01 | $128.66 | Not available in this setting | RVU26C |
| 2026-04-01 | $128.66 | Not available in this setting | RVU26B |
| 2026-01-01 | $128.66 | Not available in this setting | RVU26A |
| 2025-10-01 | Separate payment rules apply | Separate payment rules apply | RVU25D |
| 2025-07-01 | Separate payment rules apply | Separate payment rules apply | RVU25C |
| 2025-04-01 | Separate payment rules apply | Separate payment rules apply | RVU25B |
| 2025-01-01 | Separate payment rules apply | Separate payment rules apply | RVU25A |
| 2024-10-01 | Separate payment rules apply | Separate payment rules apply | RVU24D |
| 2024-07-01 | Separate payment rules apply | Separate payment rules apply | RVU24C |
| 2024-04-01 | Not in this release | Not in this release | RVU24B |
| 2024-03-09 | Not in this release | Not in this release | RVU24AR |
| 2024-01-01 | Not in this release | Not in this release | RVU24A |
| 2023-10-01 | Not in this release | Not in this release | RVU23D |
| 2023-07-01 | Not in this release | Not in this release | RVU23C |
| 2023-04-01 | Not in this release | Not in this release | RVU23B |
| 2023-01-01 | Not in this release | Not in this release | RVU23A |
| 2022-10-01 | Not in this release | Not in this release | RVU22D |
| 2022-07-01 | Not in this release | Not in this release | RVU22C |
| 2022-04-01 | Not in this release | Not in this release | RVU22B |
| 2022-01-01 | Not in this release | Not in this release | RVU22A |
| 2021-10-01 | Not in this release | Not in this release | RVU21D |
| 2021-07-01 | Not in this release | Not in this release | RVU21C |
| 2021-04-01 | Not in this release | Not in this release | RVU21B |
| 2021-01-01 | Not in this release | Not in this release | RVU21A |
| 2020-10-01 | Not in this release | Not in this release | RVU20D |
| 2020-07-01 | Not in this release | Not in this release | RVU20C |
| 2020-04-01 | Not in this release | Not in this release | RVU20B |
| 2020-01-01 | Not in this release | Not in this release | RVU20A |
| 2019-10-01 | Not in this release | Not in this release | RVU19D |
| 2019-07-01 | Not in this release | Not in this release | RVU19C |
| 2019-04-01 | Not in this release | Not in this release | RVU19B |
| 2019-01-01 | Not in this release | Not in this release | RVU19A |
| 2018-10-01 | Not in this release | Not in this release | RVU18D |
| 2018-07-01 | Not in this release | Not in this release | RVU18C |
| 2018-04-01 | Not in this release | Not in this release | RVU18B |
| 2018-01-01 | Not in this release | Not in this release | RVU18AR1 |
| 2017-10-01 | Not in this release | Not in this release | RVU17D |
| 2017-07-01 | Not in this release | Not in this release | RVU17C |
| 2017-04-01 | Not in this release | Not in this release | RVU17B |
| 2017-01-01 | Not in this release | Not in this release | RVU17A |
| 2016-10-01 | Not in this release | Not in this release | RVU16D |
| 2016-07-01 | Not in this release | Not in this release | RVU16C |
| 2016-04-01 | Not in this release | Not in this release | RVU16B |
| 2016-01-01 | Not in this release | Not in this release | RVU16A |
| 2015-10-01 | Not in this release | Not in this release | RVU15D |
| 2015-07-01 | Not in this release | Not in this release | RVU15C |
| 2015-04-01 | Not in this release | Not in this release | RVU15B |
| 2015-01-01 | Not in this release | Not in this release | RVU15A |
| 2014-10-01 | Not in this release | Not in this release | RVU14D |
| 2014-07-01 | Not in this release | Not in this release | RVU14C |
| 2014-04-01 | Not in this release | Not in this release | RVU14B |
| 2014-01-01 | Not in this release | Not in this release | RVU14A |
| 2013-10-01 | Not in this release | Not in this release | RVU13D |
| 2013-07-01 | Not in this release | Not in this release | RVU13C |
| 2013-04-01 | Not in this release | Not in this release | RVU13B |
| 2013-01-01 | Not in this release | Not in this release | RVU13AR |
Where the Puerto Rico rate applies
Puerto Rico is a Medicare payment area, not a city. Our Census mapping connects it to 292 cities and communities in Puerto Rico. Some span more than one payment area; confirm with the service ZIP.
- Aceitunas
- Adjuntas
- Aguada
- Aguadilla
- Aguas Buenas
- Aguas Claras
- Aguilita
- Aibonito
Q4315 billing questions
When should Q4315 be selected instead of another amniotic membrane product code?
Use Q4315 when the product supplied and applied is Regenelink. Choose another product-specific code when the record identifies a different product; the general tissue type alone does not determine the code.
Can Q4315 be reported without a wound-application procedure?
No. CMS identifies Q4315 as an add-on code that must be billed with a primary procedure, and its payment falls within that procedure’s global period.
How should units for Q4315 be supported?
Document the wound site and the amount of Regenelink applied. Report units on the code’s per-square-centimeter basis.
Does Q4315 include interpretation?
No. CMS classifies Q4315 as technical-component-only and indicates that a separate code covers interpretation.
What documentation supports reporting Q4315?
The record should identify Regenelink by product name, describe the treated wound and application, and support the quantity reported. It should also show the primary procedure billed with the add-on code.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
Fee sheets · Coming soon
Put Q4315 and the rest of your codes on one sheet
Your codes at your locality, with payer contracts beside Medicare.
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