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HCPCS code Q5108: Fulphila injection, per 0.5 mg2026 Medicare rate & RVUs

Pegfilgrastim-jmdb (Fulphila) is a long-acting growth factor given after chemotherapy to reduce the risk of febrile neutropenia.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare rate · Q5108

Fulphila injection, per 0.5 mg

Office or facility?

Work RVUs
0
Total RVUs
0.00
Global days
XXX

National rate · 2026

—

Not priced in the facility setting.

See every locality for Q5108 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What Q5108 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q5108 covers

Q5108 identifies pegfilgrastim-jmdb, marketed as Fulphila, a biosimilar to pegfilgrastim. This long-acting growth factor is typically administered by subcutaneous injection after myelosuppressive chemotherapy to reduce the risk of infection associated with febrile neutropenia. Oncology practices, hospital outpatient departments, and other clinicians administering the drug may report the product code for a covered dose.

CMS assigns this Part B drug code physician fee schedule status E, which excludes it from the physician fee schedule. When Medicare covers the drug, payment is generally made under another method using CMS’s quarterly Average Sales Price drug pricing files; coverage is left to the Medicare contractor’s judgment. Each unit represents 0.5 mg of pegfilgrastim-jmdb, so 6 mg corresponds to 12 units. Q5108 identifies the drug, not the act of administering the injection.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q5108 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

Q5108 office and facility rates by payment locality
Payment localityOfficeFacility
AlabamaUnavailableUnavailable
AlaskaUnavailableUnavailable
ArizonaUnavailableUnavailable
ArkansasUnavailableUnavailable
Atlanta, GAUnavailableUnavailable
Austin, TXUnavailableUnavailable
Bakersfield, CAUnavailableUnavailable
Baltimore area, MDUnavailableUnavailable
Beaumont, TXUnavailableUnavailable
Brazoria, TXUnavailableUnavailable

Q5108 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

View every state and territory as a table
Q5108 office rate range by state
State / territoryOffice rate rangeLocalities
AKNo published base rate1
ALNo published base rate1
ARNo published base rate1
AZNo published base rate1
CANo published base rate29
CONo published base rate1
CTNo published base rate1
DCNo published base rate1
DENo published base rate1
FLNo published base rate3
GANo published base rate2
GUNo published base rate1
HINo published base rate1
IANo published base rate1
IDNo published base rate1
ILNo published base rate4
INNo published base rate1
KSNo published base rate1
KYNo published base rate1
LANo published base rate2
MANo published base rate2
MDNo published base rate3
MENo published base rate2
MINo published base rate2
MNNo published base rate1
MONo published base rate3
MSNo published base rate1
MTNo published base rate1
NCNo published base rate1
NDNo published base rate1
NENo published base rate1
NHNo published base rate1
NJNo published base rate2
NMNo published base rate1
NVNo published base rate1
NYNo published base rate5
OHNo published base rate1
OKNo published base rate1
ORNo published base rate2
PANo published base rate2
PRNo published base rate1
RINo published base rate1
SCNo published base rate1
SDNo published base rate1
TNNo published base rate1
TXNo published base rate8
UTNo published base rate1
VANo published base rate2
VINo published base rate1
VTNo published base rate1
WANo published base rate2
WINo published base rate1
WVNo published base rate1
WYNo published base rate1

How the Q5108 rate is calculated

Each of Q5108’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q5108

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense0.00

0.00 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

0.0000

Conversion factor

$33.4009

Medicare rate

$0.00

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q5108

Q5108 has no global surgery period, no multiple-procedure, bilateral or assistant-at-surgery adjustment, and no professional/technical split. What changes the payment is where the service happens: the place of service on the claim decides whether Medicare pays the office or the facility rate.

Place of service · Q5108

Which rate does Medicare pay?

The POS code on the claim line (CMS-1500 box 24B).

POS 11 · non-facility rate · national

—

Q5108 isn’t priced in this setting.

Q5108 compared with similar codes

Compare codes · National

5 codes, side by side

Office or facility?

  • Q5108

    Fulphila injection, per 0.5 mg0 wRVU

    Not priced

  • Q5111

    Udenyca injection, per 0.5 mg0 wRVU

    Not priced

  • Q5120

    Pegfilgrastim-bmez, per 0.5 mg0 wRVU

    Not priced

  • Q5122

    Nyvepria injection, per 0.5 mg0 wRVU

    Not priced

  • Q5101

    Zarxio injection, per 1 mcg0 wRVU

    Not priced

How to choose

Q5111Udenyca injectionPer 0.5 mg
Q5111 identifies pegfilgrastim-cbqv (Udenyca); Q5108 is specific to pegfilgrastim-jmdb (Fulphila). Match the code to the product administered.
Q5120Pegfilgrastim-bmezPer 0.5 mg
Q5120 identifies pegfilgrastim-bmez. It is a different pegfilgrastim biosimilar from the pegfilgrastim-jmdb identified by Q5108.
Q5122Nyvepria injectionPer 0.5 mg
Q5122 identifies Nyvepria, another pegfilgrastim biosimilar. Q5108 is used for Fulphila.
Q5101Zarxio injectionPer 1 mcg
Q5101 identifies filgrastim-sndz, not pegfilgrastim-jmdb. These are different growth factor products, so code the product actually administered.

Codes related to Q5108

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to Q5108
CodeHow it relatesNational office range
Used instead
Q5111Udenyca injection, per 0.5 mgA different pegfilgrastim biosimilar code for the same general supportive-care purpose.No office rate
Q5120Pegfilgrastim-bmez, per 0.5 mgIdentifies pegfilgrastim-bmez, another biosimilar used for supportive care after chemotherapy.No office rate
Q5122Nyvepria injection, per 0.5 mgIdentifies another pegfilgrastim biosimilar product.No office rate
Q5101Zarxio injection, per 1 mcgIdentifies filgrastim-sndz, a different growth factor product used to support neutrophil recovery.No office rate

Q5108 billing questions

When should Q5108 be used instead of Q5111?

Q5108 identifies pegfilgrastim-jmdb (Fulphila). Q5111 identifies a different pegfilgrastim biosimilar, so select the code matching the product administered.

How many units represent a 6 mg dose?

Each Q5108 unit represents 0.5 mg. A 6 mg amount corresponds to 12 units.

What route is associated with Fulphila?

Fulphila is typically administered by subcutaneous injection, commonly after myelosuppressive chemotherapy.

Does Q5108 include the injection administration service?

Q5108 identifies the drug product; it is not an administration-service code.

How does Medicare treat Q5108?

CMS assigns status E, excluding Q5108 from the physician fee schedule. When covered, it is generally paid under another method using quarterly ASP drug pricing files, and coverage is left to the Medicare contractor’s judgment.

What documentation supports the units reported?

Document the product administered and the amount given so the reported units can be reconciled to the 0.5 mg per-unit measure.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates

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