Billing code 54235: Penile injectionMedicare rate & RVUs

Reports injection of a pharmacologic agent into the corpora cavernosa, commonly to induce an erection during evaluation of erectile dysfunction.

CMS RVU26DEffective Oct 1, 2026109 payment localities15.7K Medicare services in 2024

Medicare pays $94.86 for 54235 nationally in the office and $68.14 in a hospital or facility. Local office rates run $85.22–$119.38.

Medicare rate · 54235

Penile injection

Swap in your local Medicare rate.

Work RVUs
1.16
Total RVUs
2.84
Global days
000

National rate · 2026

$94.86

Office setting, before claim adjustments.

See every locality for 54235 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What 54235 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 54235 covers

A clinician injects a pharmacologic agent into the corpora cavernosa to produce an erection, commonly as part of an evaluation for erectile dysfunction. Urologists typically perform the procedure in an office or outpatient setting. The service centers on administration of the agent into the erectile tissue; it is distinct from injecting medication into a Peyronie’s plaque or irrigating the corpora for priapism.

Documentation should identify the clinical reason, the agent administered, the injection, and the observed response when assessed. The code has a 0-day global period, so same-day preoperative and postoperative care is included. When multiple procedures occur in the same session, the highest-valued procedure is paid in full and other procedures are subject to the standard 50% multiple-procedure reduction. Modifier 50 is inappropriate for this service. Medicare does not pay an assistant at surgery for it; co-surgeons and team surgery are not permitted.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 54235 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$85.22 to $119.38

$85.22$102.30$119.38
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

54235 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$86.30$62.92
Alaska*$115.30$86.85
Arizona$92.55$66.66
Arkansas$85.22$62.27
Atlanta$96.80$69.65
Austin$97.33$69.06
Bakersfield$98.54$69.26
Baltimore/Surr. Cntys$100.40$71.73
Beaumont$89.90$65.59
Brazoria$93.61$67.13

54235 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$85.22

$115.30

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
54235 office rate range by state
State / territoryOffice rate rangeLocalities
AK$115.301
AL$86.301
AR$85.221
AZ$92.551
CA$98.10–$119.3829
CO$97.501
CT$100.621
DC$106.611
DE$93.931
FL$95.13–$104.613
GA$90.30–$96.802
GU$99.751
HI$99.751
IA$87.491
ID$88.131
IL$93.23–$101.874
IN$88.551
KS$87.471
KY$88.761
LA$88.77–$92.522
MA$97.17–$105.812
MD$95.45–$106.613
ME$88.88–$92.552
MI$91.06–$96.512
MN$92.811
MO$87.68–$92.423
MS$86.451
MT$94.851
NC$89.631
ND$91.881
NE$87.811
NH$96.331
NJ$101.60–$105.822
NM$91.621
NV$94.071
NY$90.82–$111.295
OH$90.451
OK$88.271
OR$93.17–$99.872
PA$90.39–$98.622
PR$95.351
RI$96.741
SC$90.221
SD$91.531
TN$87.891
TX$89.90–$97.338
UT$91.281
VA$92.52–$106.612
VI$95.351
VT$91.871
WA$96.87–$107.482
WI$89.251
WV$90.321
WY$93.561

How the 54235 rate is calculated

Each of 54235’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 54235

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 1.16Practice expense 1.53Malpractice 0.15

2.8400 adjusted RVUs×$33.4009 conversion factor=$94.86

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for 54235

The CMS indicators that decide how 54235 is paid alongside other services.

CMS payment indicators · 54235

Penile injection

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures2Standard reduction: highest-valued procedure at 100%, others at 50%.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

54235 without 51 · national office

$94.86

Penile injection

54235-51 · Second procedure: 50%

$47.43

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

54235 compared with similar codes

Compare codes

54235 vs 54200 vs 54220 vs 54230 vs 54231: national Medicare rates

Swap in your local Medicare rate.

  • 54235
    Penile injection · 1.16 wRVU
    $94.86
  • 54200
    Plaque injection · 1.08 wRVU
    $121.25+$26.39
  • 54220
    Corporal irrigation · 2.36 wRVU
    $252.18+$157.32
  • 54230
    Cavernosography · 1.31 wRVU
    $110.56+$15.70
  • 54231
    Cavernosometry · 1.99 wRVU
    $148.97+$54.11

How to choose

54200Plaque injection
Use 54235 for pharmacologic injection into the corpora cavernosa. Code 54200 addresses injection treatment for Peyronie’s disease.
54220Corporal irrigation
54220 is irrigation of the corpora cavernosa for priapism; 54235 is pharmacologic injection for an erectile-function evaluation.
54230Cavernosography
54235 reports pharmacologic injection into the corpora cavernosa. Code 54230 is the injection procedure for cavernosography.
54231Cavernosometry
54231 reports dynamic cavernosometry, which measures penile pressure. 54235 reports the pharmacologic injection itself.

54235 billing questions

How does this differ from a Peyronie’s disease injection?

54235 describes pharmacologic injection into the corpora cavernosa, commonly to assess erectile response. Code 54200 is for injection treatment directed at Peyronie’s disease.

Is modifier 50 appropriate when both sides are injected?

No. The CMS bilateral adjustment does not apply to 54235, and modifier 50 is inappropriate.

What same-day care is included?

The 0-day global period includes same-day preoperative and postoperative care. The pharmacologic injection itself is the service reported.

How are other procedures handled in the same session?

The highest-valued procedure is paid in full, and other procedures are subject to the standard multiple-procedure reduction. The rule applies when procedures are performed in the same session.

Can an assistant or another surgeon be reported?

Medicare does not pay an assistant at surgery for 54235. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 54235PPRRVU2026_Oct_nonQPP.csv, line 6,265 (RVU26D)

Open CMS sourceHow we calculate rates

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