HCPCS Q4340: Skin substituteMedicare rate & RVUs

Report Q4340 for Simpligraft used as wound graft material, with units reflecting the square-centimeter quantity and a primary wound procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4340 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4340

Skin substitute

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4340 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4340 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4340 covers

Q4340 identifies Simpligraft, a product-specific graft supply measured by square centimeters. Wound-care clinicians and surgeons may apply the graft to a prepared wound bed when graft coverage is part of wound treatment. The product line identifies the material used; it is distinct from the service of preparing the wound and applying the graft.

Report Q4340 only with a primary procedure, and base the units on the documented square-centimeter quantity used. Record the product, wound site, amount applied, and the primary procedure supporting the supply line. CMS treats Q4340 as an add-on paid within the primary procedure’s global period. Its CMS component designation is technical-only; a separate code covers interpretation.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4340 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4340 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4340 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4340 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4340 rate is calculated

Each of Q4340’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4340

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4340

The CMS indicators that decide how Q4340 is paid alongside other services.

CMS payment indicators · Q4340

Skin substitute

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4340 compared with similar codes

Compare codes

Q4340 vs Q4341 vs Q4331 vs Q4332: national Medicare rates

Swap in your local Medicare rate.

  • Q4340
    Skin substitute · 0 wRVU
    $127.26
  • Q4341
    Wound matrix · 0 wRVU
    $127.26+$0.00
  • Q4331
    Wound matrix · 0 wRVU
    $127.26+$0.00
  • Q4332
    Wound graft · 0 wRVU
    $127.26+$0.00

How to choose

Q4341Wound matrix
Q4341 identifies Simplimax; Q4340 identifies Simpligraft. Select the supply code for the product actually used.
Q4331Wound matrix
Q4331 identifies Axolotl graft, while Q4340 identifies Simpligraft. The product used, not wound area alone, distinguishes the codes.
Q4332Wound graft
Q4332 identifies Axolotl dualgraft; Q4340 identifies Simpligraft. Report the code corresponding to the documented graft product.

Q4340 billing questions

When should Q4340 be chosen over another graft supply code?

Use Q4340 when the product used is Simpligraft. Other product-specific codes identify different graft supplies; the code is not selected solely by wound size.

Can Q4340 be reported without a primary procedure?

No. CMS identifies Q4340 as an add-on that is billed only with a primary procedure.

How should units be determined?

Report the square-centimeter quantity of Simpligraft used, supported by documentation of the amount applied to the wound.

What documentation supports the Q4340 line?

Document Simpligraft as the product used, the wound site, the square-centimeter quantity, and the primary procedure performed.

Does Q4340 include interpretation?

No. CMS classifies Q4340 as technical-component-only; a separate code covers interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4340PPRRVU2026_Oct_nonQPP.csv, line 18,427 (RVU26D)

Open CMS sourceHow we calculate rates

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