HCPCS Q4341: Wound matrixMedicare rate & RVUs

Medicare pays $127.26 for Q4341 nationally in the office. Local office rates run $109.31–$183.51.

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What Q4341 covers

Q4341 represents the Simplimax product used as a wound matrix during wound coverage or reconstruction. Wound-care clinicians and surgeons may use it when treating wounds that require a matrix product; the code identifies the material, not the wound-preparation or application work. The appropriate amount is tied to the area of product used, rather than simply the number of wounds or applications.

Report Q4341 with the primary procedure for applying the product, and document the product name, treated wound, dimensions or area covered, and quantity used. CMS classifies it as an add-on code, so it is billed only with a primary procedure and paid within that procedure’s global period. It is technical-component-only; a separate code covers interpretation. The application procedure and Q4341 represent distinct parts of the service, so the product code does not replace reporting the appropriate application procedure.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4341 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 of 109 payment localities

Q4341 rates by state

Office rate range in each state. Select a state to see its payment localities.

How the Q4341 rate is calculated

Each of Q4341’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for Q4341

The CMS indicators that decide how Q4341 is paid alongside other services.

Q4341 compared with similar codes

How to choose

Q4340Skin substitute

Q4340 identifies Simpligraft; Q4341 identifies Simplimax. Use the product-specific code matching the material supplied.

Q4342Skin substitute

Q4342 identifies Theramend rather than Simplimax. These codes distinguish products, not wound size or anatomical site.

15271Skin substitute graft

15271 reports the wound application procedure for specified body sites; Q4341 reports the Simplimax product supply used with a primary procedure.

Codes related to Q4341

Related codes aren’t interchangeable: bill the code that matches the service performed.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates