HCPCS Q4355: Wound materialMedicare rate & RVUs

Report Abio XPL or Abio XPL HY by square centimeter when this material is supplied during a separately reported wound application procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4355 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4355

Wound material

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4355 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4355 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4355 covers

Q4355 identifies Abio XPL or Abio XPL HY material supplied for placement on a wound. A clinician performing the application may use the material as part of wound coverage in an office or facility. This code identifies the specific product, rather than the clinician’s work of preparing the wound and placing the material.

Select Q4355 only when the treatment record identifies Abio XPL or Abio XPL HY, and report the quantity in square centimeters. Document the product used, the wound site, the measured area, and the accompanying application procedure. CMS classifies Q4355 as an add-on code: it is billed with a primary procedure and paid within that procedure’s global period. CMS also classifies it as technical-component-only. Q4355 therefore represents the technical portion; a separate code covers interpretation when that service is reported.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4355 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4355 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4355 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4355 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4355 rate is calculated

Each of Q4355’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4355

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4355

The CMS indicators that decide how Q4355 is paid alongside other services.

CMS payment indicators · Q4355

Wound material

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4355 compared with similar codes

Compare codes

Q4355 vs Q4356 vs Q4364 vs 15271: national Medicare rates

Swap in your local Medicare rate.

  • Q4355
    Wound material · 0 wRVU
    $127.26
  • Q4356
    Wound matrix · 0 wRVU
    $127.26+$0.00
  • Q4364
    Amniotic membrane · 0 wRVU
    $127.26+$0.00
  • 15271
    Skin substitute graft · 1.46 wRVU
    $157.99+$30.73

How to choose

Q4356Wound matrix
Both codes identify Abio products by square centimeter. Q4355 is for Abio XPL or Abio XPL HY; Q4356 is for Abio MEM or Abio HYD.
Q4364Amniotic membrane
Q4364 identifies a different named amniotic membrane product. Use Q4355 only when the product record identifies Abio XPL or Abio XPL HY.
15271Skin substitute graft
Q4355 identifies the Abio material supplied. Code 15271 describes the clinician’s skin-substitute application procedure when the wound site and size meet its criteria.

Q4355 billing questions

When is Q4355 reported instead of Q4356?

Use Q4355 for Abio XPL or Abio XPL HY. Q4356 identifies Abio MEM or Abio HYD; select the code that matches the documented product.

Does Q4355 replace the wound application procedure code?

No. Q4355 identifies the material by square centimeter and is billed with a primary procedure for its application.

How are units determined for Q4355?

The code is expressed per square centimeter. The record should identify the Abio product and support the quantity reported.

Is interpretation included in Q4355?

CMS classifies Q4355 as technical-component-only. A separate code covers interpretation when that service is reported.

How does the primary procedure’s global period affect Q4355?

Q4355 is an add-on billed with the primary procedure and paid within that procedure’s global period.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4355PPRRVU2026_Oct_nonQPP.csv, line 18,442 (RVU26D)

Open CMS sourceHow we calculate rates

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