HCPCS code Q4364: Amniotic membrane2026 Medicare rate & RVUs

Reports the AmnioBurrx XPL amniotic membrane product by square centimeter when supplied for application to a wound during a primary procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4364 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4364

Amniotic membrane

Office or facility?

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4364 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What Q4364 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4364 covers

Q4364 identifies the AmnioBurrx XPL amniotic membrane product, reported by the square centimeter. It represents the wound-covering product, not the clinician’s work to prepare the wound or apply the material. A physician or other qualified practitioner may use an amniotic membrane product during treatment of a wound, such as a chronic ulcer, in an office or outpatient setting. The product code is distinct from codes describing the application service.

Report the measured amount of product used in square-centimeter units and pair Q4364 with the applicable primary procedure. CMS treats this as an add-on code paid within the primary procedure’s global period. CMS also classifies it as technical-component-only, with a separate code covering interpretation. Documentation should identify the product, wound treated, amount applied, and the associated primary procedure so the billed units and pairing are supported.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4364 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4364 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta, GA$129.29Unavailable
Austin, TX$134.64Unavailable
Bakersfield, CA$139.47Unavailable
Baltimore area, MD$136.55Unavailable
Beaumont, TX$115.80Unavailable
Brazoria, TX$126.11Unavailable

Q4364 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4364 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4364 rate is calculated

Each of Q4364’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4364

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.00

0.00 RVUs× 1.000 GPCI

Practice expense3.81

3.81 RVUs× 1.000 GPCI

Malpractice0.00

0.00 RVUs× 1.000 GPCI

Adjusted RVUs

3.8100

Conversion factor

$33.4009

Medicare rate

$127.26

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4364

The CMS indicators that decide how Q4364 is paid alongside other services.

CMS payment indicators · Q4364

Amniotic membrane

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4364 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • Q4364

    Amniotic membrane0 wRVU

    $127.26

  • Q4363

    Amniotic membrane0 wRVU

    $127.26+$0.00

  • Q4365

    Wound product0 wRVU

    $127.26+$0.00

  • Q4366

    Amniotic membrane0 wRVU

    $127.26+$0.00

How to choose

Q4363Amniotic membrane
Q4363 identifies the AmnioBurr hydro membrane product; Q4364 identifies the XPL product. Match the claim to the specific product supplied.
Q4365Wound product
Q4365 identifies a dual-layer AmnioBurr membrane product. Q4364 is the XPL product, so the product documentation determines which code applies.
Q4366Amniotic membrane
Q4366 identifies the dual-layer AmnioBurr X-membrane product. Do not substitute it for Q4364 when the supplied product is the XPL membrane.

Q4364 billing questions

How is Q4364 different from Q4363?

Both identify AmnioBurr membrane products, but Q4364 is the XPL product. Select the code matching the product documented and supplied; Q4363 identifies the hydro product.

What should be billed with Q4364?

CMS classifies Q4364 as an add-on code, so report it only with the applicable primary procedure. For wound treatment, the primary procedure generally describes the skin-substitute application.

How are units counted?

The code is reported per square centimeter. Document the area of product used to support the units submitted.

What does the global-period rule mean for this code?

Q4364 is paid within the associated primary procedure’s global period and is not reported on its own as a standalone service.

Does Q4364 include interpretation?

No. CMS identifies Q4364 as technical-component-only; a separate code covers interpretation.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4364PPRRVU2026_Oct_nonQPP.csv, line 18,451 (RVU26D)

Open CMS sourceHow we calculate rates

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