HCPCS Q4366: Amniotic membraneMedicare rate & RVUs

Reports each square centimeter of DL AmnioBUR X-Mem used as a wound covering during a separately reported skin-substitute application procedure.

CMS RVU26DEffective Oct 1, 2026109 payment localities

Medicare pays $127.26 for Q4366 nationally in the office. Local office rates run $109.31–$183.51.

Medicare rate · Q4366

Amniotic membrane

Swap in your local Medicare rate.

Work RVUs
0
Total RVUs
3.81
Global days
ZZZ

National rate · 2026

$127.26

Office setting, before claim adjustments.

See every locality for Q4366 → · Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

On this page 10 sections
  1. Medicare rate
  2. What Q4366 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What Q4366 covers

Q4366 identifies the DL AmnioBUR X-Mem amniotic membrane product, counted by square centimeter. A wound-care physician, podiatrist, or surgeon may use it as a covering for a wound, such as a diabetic foot ulcer or venous leg ulcer, in an outpatient wound clinic or surgical setting. The product code represents the graft material, not the clinician’s work of preparing the wound or applying the graft.

Report the product only with a primary application procedure, such as the appropriate skin-substitute application code for the wound site and treated area. Document the product identity, wound location, area treated, and quantity used; report Q4366 units in square centimeters. CMS classifies Q4366 as a technical-component-only code, with interpretation covered by a separate code. Payment for this add-on is included within the primary procedure’s global period.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where Q4366 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$109.31 to $183.51

$109.31$146.41$183.51
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

Q4366 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$111.35Unavailable
Alaska*$135.53Unavailable
Arizona$123.31Unavailable
Arkansas$109.31Unavailable
Atlanta$129.29Unavailable
Austin$134.64Unavailable
Bakersfield$139.47Unavailable
Baltimore/Surr. Cntys$136.55Unavailable
Beaumont$115.80Unavailable
Brazoria$126.11Unavailable

Q4366 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$109.31

$161.49

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
Q4366 office rate range by state
State / territoryOffice rate rangeLocalities
AK$135.531
AL$111.351
AR$109.311
AZ$123.311
CA$139.47–$183.5129
CO$135.401
CT$137.061
DC$149.911
DE$125.731
FL$121.66–$132.473
GA$113.51–$129.292
GU$144.691
HI$144.691
IA$116.441
ID$117.081
IL$116.19–$130.694
IN$117.971
KS$115.041
KY$113.131
LA$112.62–$119.752
MA$134.00–$151.952
MD$128.78–$149.913
ME$117.08–$126.112
MI$116.19–$122.802
MN$130.951
MO$109.70–$121.153
MS$109.571
MT$127.261
NC$118.731
ND$127.261
NE$117.461
NH$132.471
NJ$138.97–$147.622
NM$116.701
NV$127.381
NY$120.89–$151.315
OH$116.191
OK$113.641
OR$126.75–$141.382
PA$116.82–$132.472
PR$128.661
RI$131.461
SC$117.591
SD$127.261
TN$115.681
TX$115.80–$134.648
UT$119.621
VA$125.09–$149.912
VI$128.661
VT$125.981
WA$134.00–$156.142
WI$121.911
WV$110.591
WY$127.261

How the Q4366 rate is calculated

Each of Q4366’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · Q4366

RVUs × geographic indexes × conversion factor

Swap in your local Medicare rate.

Work 0.00Practice expense 3.81Malpractice 0.00

3.8100 adjusted RVUs×$33.4009 conversion factor=$127.26

All indexes start at 1.000 (the national rate). Enter a ZIP or drag a slider.

Payment rules and modifiers for Q4366

The CMS indicators that decide how Q4366 is paid alongside other services.

CMS payment indicators · Q4366

Amniotic membrane

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical3Technical component only.

Q4366 compared with similar codes

Compare codes

Q4366 vs Q4365 vs Q4364 vs Q4367: national Medicare rates

Swap in your local Medicare rate.

  • Q4366
    Amniotic membrane · 0 wRVU
    $127.26
  • Q4365
    Wound product · 0 wRVU
    $127.26+$0.00
  • Q4364
    Amniotic membrane · 0 wRVU
    $127.26+$0.00
  • Q4367
    Amniotic tissue product · 0 wRVU
    $127.26+$0.00

How to choose

Q4365Wound product
Q4365 identifies a different AmnioBUR product. Choose between it and Q4366 by the specific product used, not simply because both are amniotic membrane grafts.
Q4364Amniotic membrane
Q4364 identifies another AmnioBUR product. Match the claim to the exact product name and labeling rather than treating these product codes as interchangeable.
Q4367Amniotic tissue product
Q4367 is a separate product code for Amniocore SL. Use Q4366 for DL AmnioBUR X-Mem, not for another amniotic membrane product.

Q4366 billing questions

How is Q4366 distinguished from other amniotic membrane codes?

Use Q4366 only when the product is specifically DL AmnioBUR X-Mem. Select a different product code when the graft’s product name or labeling identifies another product, even if it is also amniotic tissue.

Can Q4366 be billed without a wound application procedure?

No. CMS identifies it as an add-on code, so it must be reported with a primary procedure. The primary application code depends on the wound site and treated area.

How are the units reported?

Report the quantity in square centimeters. Documentation should identify the graft product and support the wound area and amount used.

Does Q4366 include the clinician’s work applying the graft?

No. Q4366 identifies the product. Report the appropriate primary application procedure for the clinician’s work; payment for Q4366 falls within that procedure’s global period.

What does technical-component-only mean for Q4366?

CMS classifies the code as technical-component-only and indicates that a separate code covers interpretation. Q4366 itself identifies the graft product.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for Q4366PPRRVU2026_Oct_nonQPP.csv, line 18,453 (RVU26D)

Open CMS sourceHow we calculate rates

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