88373 represents manual ISH morphometric analysis. This code is for the computer-assisted method.
On this page
CMS RVU26D · Effective 2026-10-01
88374 in Merced
Office / nonfacility
$288.99
Base rate per service
Facility setting
Not available in this setting
Base rate per service
Amounts below use the non-QP conversion factor for participating physicians. These are base physician payments before claim-level adjustments, not patient costs or total hospital charges.
Surgical pathology
About 88374: Computer-assisted ISH morphometric analysis
Reports computer-assisted quantitative or semiquantitative morphometric analysis of in situ hybridization findings in a tissue specimen.
A pathology laboratory uses image-analysis technology to quantify or semiquantify in situ hybridization signals in a tissue specimen. The analysis supports interpretation of molecular markers visible in cells or tissue, such as gene-copy patterns assessed in a tumor biopsy. A pathologist reviews the findings and incorporates them into the diagnostic workup; the technical work is generally performed by laboratory staff using specialized imaging equipment.
Select this service when the requested work is morphometric analysis of an in situ hybridization assay using computer-assisted technology, rather than manual measurement or tumor immunohistochemistry analysis. The record should identify the specimen, the assay and target, the quantitative or semiquantitative analysis performed, and the resulting interpretation. CMS recognizes separately priced professional and technical components: modifier 26 identifies the professional interpretation, modifier TC identifies the equipment-and-staff portion, and reporting without either modifier represents the global service.
CMS billing rules for 88374
- Professional and technical components
- Diagnostic test with a professional component (modifier 26, interpretation) and a technical component (modifier TC, equipment and staff); billing without a modifier is the global service.
Where the value comes from
- Work RVU0.91 · 11%
- Practice expense (office) RVU7.04 · 88%
- Malpractice RVU0.02 · 0%
181K
Medicare services in 2024 · #403 by national volume
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
88374 compared with similar codes
Office rates for Merced, from the same CMS release.
88360 concerns morphometric analysis of tumor immunohistochemistry using a manual method. This code concerns ISH findings analyzed with computer assistance.
88361 is computer-assisted morphometric analysis of tumor immunohistochemistry; this code is for computer-assisted morphometric analysis of ISH.
The same code, a different location
How does Merced compare?
In Bakersfield, the office rate for 88374 is $289.10—$0.11 higher than the $288.99 rate in Merced. Both use the same code, release and participation basis.
88374 across payment areas
Same release and payment basis · bars start at $0
Merced · This locality
$288.99
$289.10
$0.11 higher than Merced
$288.99
The same base rate than Merced
$288.99
The same base rate than Merced
$288.99
The same base rate than Merced
$288.99
The same base rate than Merced
$21.27 higher than Merced
Other payment areas listed in California appear first, followed by selected cross-country examples. The chart compares amounts, not distance.
Across 109 of 109 CMS payment localities with a supported office rate, 88374 ranges from $232.73 in Arkansas to $373.17 in San Jose-Sunnyvale-Santa Clara (San Benito Cnty). This is a geographic range, not an average.
The code’s RVUs stay the same in these comparisons. Geographic adjustments to work, practice expense and malpractice change the dollar amount. A city name alone may not identify the payment area for a service address.
Compare all 108 other payment areas
Madera
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Modesto
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Napa
California · 88374
Office
$342.57
Facility
Unavailable
$53.58 higher than Merced for the office setting.
Oxnard-Thousand Oaks-Ventura
California · 88374
Office
$309.60
Facility
Unavailable
$20.61 higher than Merced for the office setting.
Redding
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Rest Of California
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Riverside-San Bernardino-Ontario
California · 88374
Office
$289.23
Facility
Unavailable
$0.24 higher than Merced for the office setting.
Sacramento-Roseville-Folsom
California · 88374
Office
$305.32
Facility
Unavailable
$16.33 higher than Merced for the office setting.
Salinas
California · 88374
Office
$304.23
Facility
Unavailable
$15.24 higher than Merced for the office setting.
San Diego-Chula Vista-Carlsbad
California · 88374
Office
$312.90
Facility
Unavailable
$23.91 higher than Merced for the office setting.
San Francisco-Oakland-Berkeley (Marin Cnty)
California · 88374
Office
$365.14
Facility
Unavailable
$76.15 higher than Merced for the office setting.
San Francisco-Oakland-Berkeley (San Francisco/San Mateo/Alameda/Contra Costa Cnty)
California · 88374
Office
$365.12
Facility
Unavailable
$76.13 higher than Merced for the office setting.
San Jose-Sunnyvale-Santa Clara (San Benito Cnty)
California · 88374
Office
$373.17
Facility
Unavailable
$84.18 higher than Merced for the office setting.
San Jose-Sunnyvale-Santa Clara (Santa Clara Cnty)
California · 88374
Office
$373.08
Facility
Unavailable
$84.09 higher than Merced for the office setting.
San Luis Obispo-Paso Robles
California · 88374
Office
$299.10
Facility
Unavailable
$10.11 higher than Merced for the office setting.
Santa Cruz-Watsonville
California · 88374
Office
$317.09
Facility
Unavailable
$28.10 higher than Merced for the office setting.
Santa Maria-Santa Barbara
California · 88374
Office
$305.78
Facility
Unavailable
$16.79 higher than Merced for the office setting.
Santa Rosa-Petaluma
California · 88374
Office
$320.42
Facility
Unavailable
$31.43 higher than Merced for the office setting.
Stockton
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Vallejo
California · 88374
Office
$342.53
Facility
Unavailable
$53.54 higher than Merced for the office setting.
Visalia
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Yuba City
California · 88374
Office
$288.99
Facility
Unavailable
The same base rate than Merced for the office setting.
Dc + Md/Va Suburbs
District of Columbia · 88374
Office
$309.78
Facility
Unavailable
$20.79 higher than Merced for the office setting.
Miami
Florida · 88374
Office
$276.87
Facility
Unavailable
$12.12 lower than Merced for the office setting.
Chicago
Illinois · 88374
Office
$268.46
Facility
Unavailable
$20.53 lower than Merced for the office setting.
Manhattan
New York · 88374
Office
$306.63
Facility
Unavailable
$17.64 higher than Merced for the office setting.
Alaska*
Alaska · 88374
Office
$296.39
Facility
Unavailable
$7.40 higher than Merced for the office setting.
Alabama
Alabama · 88374
Office
$236.52
Facility
Unavailable
$52.47 lower than Merced for the office setting.
Arkansas
Arkansas · 88374
Office
$232.73
Facility
Unavailable
$56.26 lower than Merced for the office setting.
Arizona
Arizona · 88374
Office
$258.82
Facility
Unavailable
$30.17 lower than Merced for the office setting.
Colorado
Colorado · 88374
Office
$281.47
Facility
Unavailable
$7.52 lower than Merced for the office setting.
Connecticut
Connecticut · 88374
Office
$285.06
Facility
Unavailable
$3.93 lower than Merced for the office setting.
Delaware
Delaware · 88374
Office
$263.47
Facility
Unavailable
$25.52 lower than Merced for the office setting.
Fort Lauderdale
Florida · 88374
Office
$269.80
Facility
Unavailable
$19.19 lower than Merced for the office setting.
Rest Of Florida
Florida · 88374
Office
$256.19
Facility
Unavailable
$32.80 lower than Merced for the office setting.
Atlanta
Georgia · 88374
Office
$270.19
Facility
Unavailable
$18.80 lower than Merced for the office setting.
Rest Of Georgia
Georgia · 88374
Office
$240.94
Facility
Unavailable
$48.05 lower than Merced for the office setting.
Hawaii, Guam
Hawaii · 88374
Office
$298.14
Facility
Unavailable
$9.15 higher than Merced for the office setting.
Iowa
Iowa · 88374
Office
$245.82
Facility
Unavailable
$43.17 lower than Merced for the office setting.
Idaho
Idaho · 88374
Office
$247.04
Facility
Unavailable
$41.95 lower than Merced for the office setting.
East St. Louis
Illinois · 88374
Office
$248.07
Facility
Unavailable
$40.92 lower than Merced for the office setting.
Rest Of Illinois
Illinois · 88374
Office
$246.12
Facility
Unavailable
$42.87 lower than Merced for the office setting.
Suburban Chicago
Illinois · 88374
Office
$273.28
Facility
Unavailable
$15.71 lower than Merced for the office setting.
Indiana
Indiana · 88374
Office
$248.70
Facility
Unavailable
$40.29 lower than Merced for the office setting.
Kansas
Kansas · 88374
Office
$243.30
Facility
Unavailable
$45.69 lower than Merced for the office setting.
Kentucky
Kentucky · 88374
Office
$240.05
Facility
Unavailable
$48.94 lower than Merced for the office setting.
New Orleans
Louisiana · 88374
Office
$252.42
Facility
Unavailable
$36.57 lower than Merced for the office setting.
Rest Of Louisiana
Louisiana · 88374
Office
$239.14
Facility
Unavailable
$49.85 lower than Merced for the office setting.
Metropolitan Boston
Massachusetts · 88374
Office
$313.00
Facility
Unavailable
$24.01 higher than Merced for the office setting.
Rest Of Massachusetts
Massachusetts · 88374
Office
$279.02
Facility
Unavailable
$9.97 lower than Merced for the office setting.
Baltimore/Surr. Cntys
Maryland · 88374
Office
$284.02
Facility
Unavailable
$4.97 lower than Merced for the office setting.
Rest Of Maryland
Maryland · 88374
Office
$269.28
Facility
Unavailable
$19.71 lower than Merced for the office setting.
Rest Of Maine
Maine · 88374
Office
$247.14
Facility
Unavailable
$41.85 lower than Merced for the office setting.
Southern Maine
Maine · 88374
Office
$263.84
Facility
Unavailable
$25.15 lower than Merced for the office setting.
Detroit
Michigan · 88374
Office
$258.43
Facility
Unavailable
$30.56 lower than Merced for the office setting.
Rest Of Michigan
Michigan · 88374
Office
$245.83
Facility
Unavailable
$43.16 lower than Merced for the office setting.
Minnesota
Minnesota · 88374
Office
$272.55
Facility
Unavailable
$16.44 lower than Merced for the office setting.
Metropolitan Kansas City
Missouri · 88374
Office
$251.85
Facility
Unavailable
$37.14 lower than Merced for the office setting.
Metropolitan St. Louis
Missouri · 88374
Office
$254.92
Facility
Unavailable
$34.07 lower than Merced for the office setting.
Rest Of Missouri
Missouri · 88374
Office
$233.74
Facility
Unavailable
$55.25 lower than Merced for the office setting.
Mississippi
Mississippi · 88374
Office
$233.35
Facility
Unavailable
$55.64 lower than Merced for the office setting.
Montana**
Montana · 88374
Office
$266.20
Facility
Unavailable
$22.79 lower than Merced for the office setting.
North Carolina
North Carolina · 88374
Office
$250.21
Facility
Unavailable
$38.78 lower than Merced for the office setting.
North Dakota**
North Dakota · 88374
Office
$265.81
Facility
Unavailable
$23.18 lower than Merced for the office setting.
Nebraska
Nebraska · 88374
Office
$247.68
Facility
Unavailable
$41.31 lower than Merced for the office setting.
New Hampshire
New Hampshire · 88374
Office
$275.76
Facility
Unavailable
$13.23 lower than Merced for the office setting.
Northern Nj
New Jersey · 88374
Office
$305.79
Facility
Unavailable
$16.80 higher than Merced for the office setting.
Rest Of New Jersey
New Jersey · 88374
Office
$289.12
Facility
Unavailable
$0.13 higher than Merced for the office setting.
New Mexico
New Mexico · 88374
Office
$246.82
Facility
Unavailable
$42.17 lower than Merced for the office setting.
Nevada**
Nevada · 88374
Office
$266.33
Facility
Unavailable
$22.66 lower than Merced for the office setting.
Nyc Suburbs/Long Island
New York · 88374
Office
$313.16
Facility
Unavailable
$24.17 higher than Merced for the office setting.
Poughkpsie/N Nyc Suburbs
New York · 88374
Office
$290.05
Facility
Unavailable
$1.06 higher than Merced for the office setting.
Queens
New York · 88374
Office
$311.24
Facility
Unavailable
$22.25 higher than Merced for the office setting.
Rest Of New York
New York · 88374
Office
$254.25
Facility
Unavailable
$34.74 lower than Merced for the office setting.
Ohio
Ohio · 88374
Office
$245.75
Facility
Unavailable
$43.24 lower than Merced for the office setting.
Oklahoma
Oklahoma · 88374
Office
$240.90
Facility
Unavailable
$48.09 lower than Merced for the office setting.
Portland
Oregon · 88374
Office
$292.62
Facility
Unavailable
$3.63 higher than Merced for the office setting.
Rest Of Oregon
Oregon · 88374
Office
$265.07
Facility
Unavailable
$23.92 lower than Merced for the office setting.
Metropolitan Philadelphia
Pennsylvania · 88374
Office
$276.52
Facility
Unavailable
$12.47 lower than Merced for the office setting.
Rest Of Pennsylvania
Pennsylvania · 88374
Office
$246.89
Facility
Unavailable
$42.10 lower than Merced for the office setting.
Puerto Rico
Puerto Rico · 88374
Office
$268.78
Facility
Unavailable
$20.21 lower than Merced for the office setting.
Rhode Island
Rhode Island · 88374
Office
$274.47
Facility
Unavailable
$14.52 lower than Merced for the office setting.
South Carolina
South Carolina · 88374
Office
$248.23
Facility
Unavailable
$40.76 lower than Merced for the office setting.
South Dakota**
South Dakota · 88374
Office
$265.76
Facility
Unavailable
$23.23 lower than Merced for the office setting.
Tennessee
Tennessee · 88374
Office
$244.50
Facility
Unavailable
$44.49 lower than Merced for the office setting.
Austin
Texas · 88374
Office
$279.83
Facility
Unavailable
$9.16 lower than Merced for the office setting.
Beaumont
Texas · 88374
Office
$244.99
Facility
Unavailable
$44.00 lower than Merced for the office setting.
Brazoria
Texas · 88374
Office
$264.19
Facility
Unavailable
$24.80 lower than Merced for the office setting.
Dallas
Texas · 88374
Office
$265.44
Facility
Unavailable
$23.55 lower than Merced for the office setting.
Fort Worth
Texas · 88374
Office
$263.10
Facility
Unavailable
$25.89 lower than Merced for the office setting.
Galveston
Texas · 88374
Office
$264.69
Facility
Unavailable
$24.30 lower than Merced for the office setting.
Houston
Texas · 88374
Office
$265.05
Facility
Unavailable
$23.94 lower than Merced for the office setting.
Rest Of Texas
Texas · 88374
Office
$254.15
Facility
Unavailable
$34.84 lower than Merced for the office setting.
Utah
Utah · 88374
Office
$252.03
Facility
Unavailable
$36.96 lower than Merced for the office setting.
Virginia
Virginia · 88374
Office
$262.01
Facility
Unavailable
$26.98 lower than Merced for the office setting.
Virgin Islands
United States Virgin Islands · 88374
Office
$268.78
Facility
Unavailable
$20.21 lower than Merced for the office setting.
Vermont
Vermont · 88374
Office
$263.52
Facility
Unavailable
$25.47 lower than Merced for the office setting.
Rest Of Washington
Washington · 88374
Office
$278.90
Facility
Unavailable
$10.09 lower than Merced for the office setting.
Seattle (King Cnty)
Washington · 88374
Office
$320.98
Facility
Unavailable
$31.99 higher than Merced for the office setting.
Wisconsin
Wisconsin · 88374
Office
$255.87
Facility
Unavailable
$33.12 lower than Merced for the office setting.
West Virginia
West Virginia · 88374
Office
$235.69
Facility
Unavailable
$53.30 lower than Merced for the office setting.
Wyoming**
Wyoming · 88374
Office
$266.03
Facility
Unavailable
$22.96 lower than Merced for the office setting.
See how rates vary across the country
88374 · Office / nonfacility · Non-QP. Choose a state to explore its payment localities. A range means the amount varies within that state.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$232.73
$331.08
Color shows the midpoint of each state’s locality range.
View all state and territory rates as a table
| State / territory | Rate range | Localities |
|---|---|---|
| AK | $296.39 | 1 |
| AL | $236.52 | 1 |
| AR | $232.73 | 1 |
| AZ | $258.82 | 1 |
| CA | $288.99–$373.17 | 29 |
| CO | $281.47 | 1 |
| CT | $285.06 | 1 |
| DC | $309.78 | 1 |
| DE | $263.47 | 1 |
| FL | $256.19–$276.87 | 3 |
| GA | $240.94–$270.19 | 2 |
| GU | $298.14 | 1 |
| HI | $298.14 | 1 |
| IA | $245.82 | 1 |
| ID | $247.04 | 1 |
| IL | $246.12–$273.28 | 4 |
| IN | $248.70 | 1 |
| KS | $243.30 | 1 |
| KY | $240.05 | 1 |
| LA | $239.14–$252.42 | 2 |
| MA | $279.02–$313.00 | 2 |
| MD | $269.28–$309.78 | 3 |
| ME | $247.14–$263.84 | 2 |
| MI | $245.83–$258.43 | 2 |
| MN | $272.55 | 1 |
| MO | $233.74–$254.92 | 3 |
| MS | $233.35 | 1 |
| MT | $266.20 | 1 |
| NC | $250.21 | 1 |
| ND | $265.81 | 1 |
| NE | $247.68 | 1 |
| NH | $275.76 | 1 |
| NJ | $289.12–$305.79 | 2 |
| NM | $246.82 | 1 |
| NV | $266.33 | 1 |
| NY | $254.25–$313.16 | 5 |
| OH | $245.75 | 1 |
| OK | $240.90 | 1 |
| OR | $265.07–$292.62 | 2 |
| PA | $246.89–$276.52 | 2 |
| PR | $268.78 | 1 |
| RI | $274.47 | 1 |
| SC | $248.23 | 1 |
| SD | $265.76 | 1 |
| TN | $244.50 | 1 |
| TX | $244.99–$279.83 | 8 |
| UT | $252.03 | 1 |
| VA | $262.01–$309.78 | 2 |
| VI | $268.78 | 1 |
| VT | $263.52 | 1 |
| WA | $278.90–$320.98 | 2 |
| WI | $255.87 | 1 |
| WV | $235.69 | 1 |
| WY | $266.03 | 1 |
Where does this rate apply?
Merced is a Medicare payment area. Our Census mapping connects it to 24 cities and communities in California, including the examples shown here.
Some communities span more than one payment area. Follow a city link to compare all of its mapped areas, or check the service-location ZIP above for an address-level starting point.
Use this rate
What is a percentage of Medicare worth?
Turn a percentage into dollars for 88374 in Merced. This uses the base rate on this page, so the locality and release stay consistent.
Reference amount per service
$317.89
$288.99 × 110% = $317.89
A contract may specify another Medicare year or additional adjustments. This is percentage arithmetic on the displayed base rate, not a claim adjudication.
Working with a whole code list?
Compare an offer across your annual code mix, including an older Medicare schedule or flat per-code rates.
How this local rate is calculated
Each RVU component is multiplied by its own geographic practice cost index (GPCI). The three adjusted components are added, then multiplied by the conversion factor. These are the inputs used for 88374 in Merced.
PPRRVU2026_Oct_nonQPP.csv
11,310
- Code
- 88374
- Physician work
- 0.91
- Practice expense
- 7.04
- Malpractice
- 0.02
GPCI2026.csv
15
- Locality
- Merced
- Physician work
- 1.017
- Practice expense
- 1.096
- Malpractice
- 0.536
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.91 | × 1.017 | 0.9255 |
| Practice expense | 7.04 | × 1.096 | 7.7158 |
| Malpractice | 0.02 | × 0.536 | 0.0107 |
| Total RVUs | 8.6520 | ||
| Conversion factor | × 33.4009 | ||
Office / nonfacility rate, Merced$288.99
Open 88374 in the RVU calculator →
Explore RVUs, geographic factors and the full formula
Office / nonfacility
| Component | RVU | Local GPCI |
|---|---|---|
| Work | 0.91 | 1.017 |
| Practice expense | 7.04 | 1.096 |
| Malpractice | 0.02 | 0.536 |
(0.91 × 1.017 + 7.04 × 1.096 + 0.02 × 0.536) × $33.4009 = $288.99
The office and facility calculations use their respective practice-expense RVUs. The facility amount here is the physician fee, not a separate hospital or facility bill.
How this rate has changed
88374 · Office / nonfacility
$288.99
Effective 2026-10-01
The base rate is $3.04 higher than on 2025-10-01, moving from $285.95 to $288.99 (1.1%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$285.95changed to$288.99
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 0.93 changed to 0.91
- Practice expense RVU 7.21 changed to 7.04
- Malpractice RVU 0.03 changed to 0.02
- Work GPCI 1.014 changed to 1.017
- Practice expense GPCI 1.093 changed to 1.096
- Malpractice GPCI 0.560 changed to 0.536
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
Earliest loaded release: $285.95
Held through RVU25B, RVU25C, RVU25D.
Explore release dates and calculate this code in an earlier period →
Each row uses the accepted CMS release effective on that date and the same contractor and locality identifiers. Missing rates stay visible. Historical boundaries may differ; verify the service address for an older claim.
Inspect every release and its CMS source
| Effective from | Office / nonfacility | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $288.99 | Not available in this setting | RVU26D |
| 2026-07-01 | $288.99 | Not available in this setting | RVU26C |
| 2026-04-01 | $288.99 | Not available in this setting | RVU26B |
| 2026-01-01 | $288.99 | Not available in this setting | RVU26A |
| 2025-10-01 | $285.95 | Not available in this setting | RVU25D |
| 2025-07-01 | $285.95 | Not available in this setting | RVU25C |
| 2025-04-01 | $285.95 | Not available in this setting | RVU25B |
| 2025-01-01 | $285.95 | Not available in this setting | RVU25A |
88374 billing questions
How does this differ from manual ISH morphometric analysis?
This code is for quantitative or semiquantitative ISH morphometric analysis performed with computer-assisted technology. Use the manual counterpart when the morphometric analysis is performed manually.
Is this the same as tumor immunohistochemistry analysis?
No. This service analyzes in situ hybridization findings; tumor immunohistochemistry analysis evaluates immunostaining and is reported with the applicable IHC morphometric-analysis code.
Which modifiers identify the components?
Modifier 26 reports the professional interpretation, and modifier TC reports the technical service, including equipment and staff. Without either modifier, the claim represents the global service.
What documentation supports reporting this service?
Document the specimen and ISH assay, the use of computer-assisted quantitative or semiquantitative morphometric analysis, and the pathologist's interpretation of the findings.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense, and malpractice RVUs, adjusted by each locality’s geographic indices and the applicable conversion factor. Unavailable or separately priced services are labeled rather than assigned a made-up amount.
Source: RVU26D. Effective 2026-10-01 through the day before 2027-01-01.
