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CPT code 52287: Bladder chemodenervation, cystoscopic injection2026 Medicare rate & RVUs in Mississippi

Reports cystoscopic injection of a chemodenervation agent into the bladder for conditions such as overactive bladder or neurogenic detrusor overactivity.

CMS RVU26DEffective Oct 1, 2026One payment locality84K Medicare services in 2024

In Mississippi, Medicare pays $325.91 for 52287 in the office and $140.99 when it’s performed in a hospital or facility.

$325.91Office (non-facility)
$140.99Hospital or facility
−10.4%vs the national office rate ($363.74)

Check a contract rate as a % of Medicare · 52287 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 52287 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Mississippi
  2. What 52287 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 52287 covers

A urologist typically performs this procedure by passing a cystoscope through the urethra and injecting a chemodenervation agent into the bladder wall. Common indications include overactive bladder with inadequate response or intolerance to medication and neurogenic detrusor overactivity. The code represents the cystoscopic injection service, not a biopsy or treatment of a bladder lesion. When the practice supplies onabotulinumtoxinA, the drug may be reported separately using the applicable drug code.

Report the service for the cystoscopic chemodenervation session; document the indication, agent and dose, injection sites, and procedure performed. The procedure has a 0-day global period, so same-day preoperative and postoperative care is included. When related endoscopies are performed together, endoscopy-family pricing applies. Modifier 50 is inappropriate for this service. Medicare does not pay an assistant at surgery, and co-surgeon and team-surgery reporting are not permitted. The physician fee schedule has different practice-expense inputs for office and facility settings.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Mississippi compares for 52287

Across 109 of 109 payment localities, the office rate for 52287 runs from $322.20 in Arkansas to $476.90 in San Benito County, CA. Mississippi pays $325.91. The RVUs are the same everywhere; the geographic indexes change the dollars.

52287 in Mississippi vs other payment areas
  1. Mississippi · this page$325.91
  2. Los Angeles, CA · California$408.05+$82.14
  3. Washington, DC area · District of Columbia$414.63+$88.72
  4. Miami, FL · Florida$395.75+$69.84
  5. Chicago, IL · Illinois$384.29+$58.38
  6. Manhattan, NY · New York$418.54+$92.63
  7. Alaska · Alaska$425.33+$99.42

Other areas in Mississippi first, then benchmark localities. Bars start at $0.

Every other payment area

52287 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$326.86$138.94
ArkansasArkansas$322.20$137.72
ArizonaArizona$354.07$145.96
Bakersfield, CACalifornia$383.64$148.25
Chico, CACalifornia$382.38$146.99
El Centro, CACalifornia$382.45$147.07
Fresno, CACalifornia$382.38$146.99
Hanford, CACalifornia$382.38$146.99

52287 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$322.20

$429.64

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
52287 office rate range by state
State / territoryOffice rate rangeLocalities
AK$425.331
AL$326.861
AR$322.201
AZ$354.071
CA$382.38–$476.9029
CO$377.531
CT$387.711
DC$414.631
DE$359.861
FL$360.17–$395.753
GA$340.02–$370.862
GU$391.281
HI$391.281
IA$334.241
ID$336.551
IL$350.49–$384.294
IN$338.461
KS$333.081
KY$335.301
LA$334.94–$351.222
MA$375.48–$413.992
MD$366.54–$414.633
ME$338.69–$356.232
MI$344.26–$365.012
MN$360.731
MO$329.53–$352.003
MS$325.911
MT$363.711
NC$342.131
ND$355.201
NE$335.921
NH$371.991
NJ$391.85–$410.502
NM$346.271
NV$361.581
NY$347.21–$429.055
OH$342.521
OK$334.301
OR$358.49–$388.942
PA$342.84–$378.442
PR$366.221
RI$372.261
SC$342.951
SD$354.201
TN$334.781
TX$340.65–$376.538
UT$347.561
VA$355.35–$414.632
VI$366.221
VT$354.191
WA$374.65–$421.972
WI$343.501
WV$337.811
WY$360.001

See 52287 in every payment locality

How the 52287 rate is calculated

Each of 52287’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 52287

RVUs × geographic indexes × conversion factor

Office or facility?

Work3.12

3.12 RVUs× 1.000 GPCI

Practice expense7.34

7.34 RVUs× 1.000 GPCI

Malpractice0.43

0.43 RVUs× 1.000 GPCI

Adjusted RVUs

10.8900

Conversion factor

$33.4009

Medicare rate

$363.74

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Mississippi inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,129

Code
52287
Physician work
3.12
Practice expense
7.34
Malpractice
0.43

GPCI2026.csv

67

Locality
Mississippi
Physician work
1.000
Practice expense
0.861
Malpractice
0.739
Office calculation for 52287 in Mississippi
ComponentRVULocality factorAdjusted
Physician work3.12× 1.0003.1200
Practice expense7.34× 0.8616.3197
Malpractice0.43× 0.7390.3178
Total RVUs9.7575
Conversion factor× 33.4009

Office rate, Mississippi$325.91

Office: (3.12 × 1 + 7.34 × 0.861 + 0.43 × 0.739) × $33.4009 = $325.91

Facility: (3.12 × 1 + 0.91 × 0.861 + 0.43 × 0.739) × $33.4009 = $140.99

Open 52287 in the RVU calculator

Payment rules and modifiers for 52287

The CMS indicators that decide how 52287 is paid alongside other services.

CMS payment indicators · 52287

Bladder chemodenervation, cystoscopic injection

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

52287 without 51 · national office

$363.74

Bladder chemodenervation, cystoscopic injection

52287-51 · Second procedure: 50%

$181.87

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

Codes related to 52287

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 52287
CodeHow it relatesOffice range, Mississippi
Often billed with
J0585OnabotulinumtoxinA, per 1 unitMay report the onabotulinumtoxinA drug separately when the practice supplies it.No office rate
52204Cystoscopic biopsy, bladder tissue samplingMay be considered for a separately indicated bladder biopsy during the same encounter.$316.35
52224Bladder lesion treatment, lesions under 0.5 cmMay be considered for distinct treatment of a bladder lesion during the same encounter.$670.88

How 52287 has changed in Mississippi

52287 · Office / nonfacility

$325.91

Effective 2026-10-01

The base rate is $9.41 higher than on 2025-10-01, moving from $316.50 to $325.91 (3.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $316.50changed to$325.91

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 3.20 changed to 3.12
    • Practice expense RVU 7.35 changed to 7.34
    • Malpractice RVU 0.42 changed to 0.43
    • Practice expense GPCI 0.852 changed to 0.861
    • Malpractice GPCI 0.768 changed to 0.739

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $344.17changed to$316.50

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 8.01 changed to 7.35
    • Malpractice RVU 0.41 changed to 0.42

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $338.56changed to$344.17

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $349.78changed to$338.56

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 8.06 changed to 8.01
    • Practice expense GPCI 0.847 changed to 0.852
    • Malpractice GPCI 0.720 changed to 0.768

  5. January 1, 2023

    RVU23A

    $358.67changed to$349.78

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 8.19 changed to 8.06
    • Malpractice RVU 0.40 changed to 0.41
    • Practice expense GPCI 0.842 changed to 0.847
    • Malpractice GPCI 0.671 changed to 0.720

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $350.54changed to$358.67

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 7.82 changed to 8.19
    • Malpractice RVU 0.39 changed to 0.40

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $329.18changed to$350.54

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 6.68 changed to 7.82
    • Practice expense GPCI 0.856 changed to 0.842
    • Malpractice GPCI 0.521 changed to 0.671

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $311.07changed to$329.18

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 6.09 changed to 6.68
    • Malpractice RVU 0.36 changed to 0.39
    • Practice expense GPCI 0.870 changed to 0.856
    • Malpractice GPCI 0.370 changed to 0.521

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $289.61changed to$311.07

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 5.42 changed to 6.09
    • Malpractice RVU 0.35 changed to 0.36

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $286.73changed to$289.61

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 5.32 changed to 5.42
    • Malpractice RVU 0.36 changed to 0.35
    • Practice expense GPCI 0.867 changed to 0.870
    • Malpractice GPCI 0.492 changed to 0.370

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $285.50changed to$286.73

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 5.27 changed to 5.32
    • Practice expense GPCI 0.864 changed to 0.867
    • Malpractice GPCI 0.613 changed to 0.492

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $285.91changed to$285.50

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 5.25 changed to 5.27

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $284.49changed to$285.91

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $282.09changed to$284.49

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 5.15 changed to 5.25
    • Malpractice RVU 0.32 changed to 0.36
    • Practice expense GPCI 0.865 changed to 0.864
    • Malpractice GPCI 0.687 changed to 0.613

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $281.24changed to$282.09

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 5.56 changed to 5.15
    • Malpractice RVU 0.33 changed to 0.32
    • Practice expense GPCI 0.866 changed to 0.865
    • Malpractice GPCI 0.761 changed to 0.687

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $281.24

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$325.91$140.99RVU26D
2026-07-01$325.91$140.99RVU26C
2026-04-01$325.91$140.99RVU26B
2026-01-01$325.91$140.99RVU26A
2025-10-01$316.50$153.08RVU25D
2025-07-01$316.50$153.08RVU25C
2025-04-01$316.50$153.08RVU25B
2025-01-01$316.50$153.08RVU25A
2024-10-01$344.17$156.14RVU24D
2024-07-01$344.17$156.14RVU24C
2024-04-01$344.17$156.14RVU24B
2024-03-09$344.17$156.14RVU24AR
2024-01-01$338.56$153.59RVU24A
2023-10-01$349.78$157.19RVU23D
2023-07-01$349.78$157.19RVU23C
2023-04-01$349.78$157.19RVU23B
2023-01-01$349.78$157.19RVU23A
2022-10-01$358.67$158.49RVU22D
2022-07-01$358.67$158.49RVU22C
2022-04-01$358.67$158.49RVU22B
2022-01-01$358.67$158.49RVU22A
2021-10-01$350.54$159.57RVU21D
2021-07-01$350.54$159.57RVU21C
2021-04-01$350.54$159.57RVU21B
2021-01-01$350.54$159.57RVU21A
2020-10-01$329.18$162.98RVU20D
2020-07-01$329.18$162.98RVU20C
2020-04-01$329.18$162.98RVU20B
2020-01-01$329.18$162.98RVU20A
2019-10-01$311.07$161.83RVU19D
2019-07-01$311.07$161.83RVU19C
2019-04-01$311.07$161.83RVU19B
2019-01-01$311.07$161.83RVU19A
2018-10-01$289.61$162.14RVU18D
2018-07-01$289.61$162.14RVU18C
2018-04-01$289.61$162.14RVU18B
2018-01-01$289.61$162.14RVU18AR1
2017-10-01$286.73$162.90RVU17D
2017-07-01$286.73$162.90RVU17C
2017-04-01$286.73$162.90RVU17B
2017-01-01$286.73$162.90RVU17A
2016-10-01$285.50$163.00RVU16D
2016-07-01$285.50$163.00RVU16C
2016-04-01$285.50$163.00RVU16B
2016-01-01$285.50$163.00RVU16A
2015-10-01$285.91$163.59RVU15D
2015-07-01$285.91$163.59RVU15C
2015-04-01$284.49$162.77RVU15B
2015-01-01$284.49$162.77RVU15A
2014-10-01$282.09$162.79RVU14D
2014-07-01$282.09$162.79RVU14C
2014-04-01$282.09$162.79RVU14B
2014-01-01$282.09$162.79RVU14A
2013-10-01$281.24$157.19RVU13D
2013-07-01$281.24$157.19RVU13C
2013-04-01$281.24$157.19RVU13B
2013-01-01$281.24$157.19RVU13AR

Price 52287 for an earlier date of service

Where the Mississippi rate applies

Mississippi is a Medicare payment area, not a city. Our Census mapping connects it to 427 cities and communities in Mississippi. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Aberdeen
  • Ackerman
  • Agricola
  • Alcorn State University
  • Algoma
  • Alligator
  • Amory

Browse all communities in Mississippi

52287 billing questions

How is this different from cystoscopy with biopsy?

52287 reports injections intended to chemodenervate the bladder. A biopsy code is for sampling bladder tissue, not for the therapeutic injection.

Can the medication be reported separately?

When the practice supplies onabotulinumtoxinA, report the drug separately using the applicable drug code. The cystoscopic injection service is reported with 52287.

Should modifier 50 be appended?

No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.

What happens when another related endoscopy is performed at the same session?

CMS endoscopy-family pricing applies when related endoscopies are performed together. Documentation should identify each distinct service performed.

What documentation supports 52287?

Document the bladder condition being treated, the chemodenervation agent and dose, the cystoscopic injection procedure, and the sites treated.

Can an assistant or co-surgeon be reported?

Medicare does not pay an assistant at surgery for this service. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 52287PPRRVU2026_Oct_nonQPP.csv, line 6,129 (RVU26D)
Geographic factors for MississippiGPCI2026.csv, line 67 (RVU26D)

Open CMS sourceHow we calculate rates

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