CPT code 52287: Bladder chemodenervation, cystoscopic injection2026 Medicare rate & RVUs in North Carolina

Reports cystoscopic injection of a chemodenervation agent into the bladder for conditions such as overactive bladder or neurogenic detrusor overactivity.

CMS RVU26DEffective Oct 1, 2026One payment locality84K Medicare services in 2024

In North Carolina, Medicare pays $342.13 for 52287 in the office and $141.75 when it’s performed in a hospital or facility.

$342.13Office (non-facility)
$141.75Hospital or facility
−5.9%vs the national office rate ($363.74)

Check a contract rate as a % of Medicare · 52287 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 52287 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in North Carolina
  2. What 52287 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 52287 covers

A urologist typically performs this procedure by passing a cystoscope through the urethra and injecting a chemodenervation agent into the bladder wall. Common indications include overactive bladder with inadequate response or intolerance to medication and neurogenic detrusor overactivity. The code represents the cystoscopic injection service, not a biopsy or treatment of a bladder lesion. When the practice supplies onabotulinumtoxinA, the drug may be reported separately using the applicable drug code.

Report the service for the cystoscopic chemodenervation session; document the indication, agent and dose, injection sites, and procedure performed. The procedure has a 0-day global period, so same-day preoperative and postoperative care is included. When related endoscopies are performed together, endoscopy-family pricing applies. Modifier 50 is inappropriate for this service. Medicare does not pay an assistant at surgery, and co-surgeon and team-surgery reporting are not permitted. The physician fee schedule has different practice-expense inputs for office and facility settings.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How North Carolina compares for 52287

Across 109 of 109 payment localities, the office rate for 52287 runs from $322.20 in Arkansas to $476.90 in San Benito County, CA. North Carolina pays $342.13. The RVUs are the same everywhere; the geographic indexes change the dollars.

52287 in North Carolina vs other payment areas
  1. North Carolina · this page$342.13
  2. Los Angeles, CA · California$408.05+$65.92
  3. Washington, DC area · District of Columbia$414.63+$72.50
  4. Miami, FL · Florida$395.75+$53.62
  5. Chicago, IL · Illinois$384.29+$42.16
  6. Manhattan, NY · New York$418.54+$76.41
  7. Alaska · Alaska$425.33+$83.20

Other areas in North Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

52287 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$326.86$138.94
ArkansasArkansas$322.20$137.72
ArizonaArizona$354.07$145.96
Bakersfield, CACalifornia$383.64$148.25
Chico, CACalifornia$382.38$146.99
El Centro, CACalifornia$382.45$147.07
Fresno, CACalifornia$382.38$146.99
Hanford, CACalifornia$382.38$146.99

52287 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$322.20

$429.64

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
52287 office rate range by state
State / territoryOffice rate rangeLocalities
AK$425.331
AL$326.861
AR$322.201
AZ$354.071
CA$382.38–$476.9029
CO$377.531
CT$387.711
DC$414.631
DE$359.861
FL$360.17–$395.753
GA$340.02–$370.862
GU$391.281
HI$391.281
IA$334.241
ID$336.551
IL$350.49–$384.294
IN$338.461
KS$333.081
KY$335.301
LA$334.94–$351.222
MA$375.48–$413.992
MD$366.54–$414.633
ME$338.69–$356.232
MI$344.26–$365.012
MN$360.731
MO$329.53–$352.003
MS$325.911
MT$363.711
NC$342.131
ND$355.201
NE$335.921
NH$371.991
NJ$391.85–$410.502
NM$346.271
NV$361.581
NY$347.21–$429.055
OH$342.521
OK$334.301
OR$358.49–$388.942
PA$342.84–$378.442
PR$366.221
RI$372.261
SC$342.951
SD$354.201
TN$334.781
TX$340.65–$376.538
UT$347.561
VA$355.35–$414.632
VI$366.221
VT$354.191
WA$374.65–$421.972
WI$343.501
WV$337.811
WY$360.001

See 52287 in every payment locality

How the 52287 rate is calculated

Each of 52287’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 52287

RVUs × geographic indexes × conversion factor

Office or facility?

Work3.12

3.12 RVUs× 1.000 GPCI

Practice expense7.34

7.34 RVUs× 1.000 GPCI

Malpractice0.43

0.43 RVUs× 1.000 GPCI

Adjusted RVUs

10.8900

Conversion factor

$33.4009

Medicare rate

$363.74

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact North Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,129

Code
52287
Physician work
3.12
Practice expense
7.34
Malpractice
0.43

GPCI2026.csv

83

Locality
North Carolina
Physician work
1.000
Practice expense
0.933
Malpractice
0.639
Office calculation for 52287 in North Carolina
ComponentRVULocality factorAdjusted
Physician work3.12× 1.0003.1200
Practice expense7.34× 0.9336.8482
Malpractice0.43× 0.6390.2748
Total RVUs10.2430
Conversion factor× 33.4009

Office rate, North Carolina$342.13

Office: (3.12 × 1 + 7.34 × 0.933 + 0.43 × 0.639) × $33.4009 = $342.13

Facility: (3.12 × 1 + 0.91 × 0.933 + 0.43 × 0.639) × $33.4009 = $141.75

Open 52287 in the RVU calculator

Payment rules and modifiers for 52287

The CMS indicators that decide how 52287 is paid alongside other services.

CMS payment indicators · 52287

Bladder chemodenervation, cystoscopic injection

RuleCMS valueWhat it means
Global period000Same-day global: pre- and post-op care on the day of the procedure is included.
Multiple procedures3Endoscopy family rules apply.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)1Not paid (statutory restriction).
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

What modifiers do to the payment

Modifier 51 · payment effect

With and without the modifier

52287 without 51 · national office

$363.74

Bladder chemodenervation, cystoscopic injection

52287-51 · Second procedure: 50%

$181.87

When this isn’t the highest-valued procedure in the session, Medicare pays 50% of its fee schedule amount (the highest is paid at 100%).

When to use modifier 51

How 52287 has changed in North Carolina

52287 · Office / nonfacility

$342.13

Effective 2026-10-01

The base rate is $9.43 higher than on 2025-10-01, moving from $332.70 to $342.13 (2.8%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $332.70changed to$342.13

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 3.20 changed to 3.12
    • Practice expense RVU 7.35 changed to 7.34
    • Malpractice RVU 0.42 changed to 0.43
    • Practice expense GPCI 0.926 changed to 0.933
    • Malpractice GPCI 0.665 changed to 0.639

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $362.50changed to$332.70

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 8.01 changed to 7.35
    • Malpractice RVU 0.41 changed to 0.42

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $356.58changed to$362.50

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $371.94changed to$356.58

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 8.06 changed to 8.01
    • Practice expense GPCI 0.927 changed to 0.926
    • Malpractice GPCI 0.742 changed to 0.665
  5. January 1, 2023

    RVU23A

    $385.10changed to$371.94

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 8.19 changed to 8.06
    • Malpractice RVU 0.40 changed to 0.41
    • Practice expense GPCI 0.928 changed to 0.927
    • Malpractice GPCI 0.819 changed to 0.742

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $376.02changed to$385.10

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 7.82 changed to 8.19
    • Malpractice RVU 0.39 changed to 0.40

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $350.34changed to$376.02

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 6.68 changed to 7.82
    • Practice expense GPCI 0.930 changed to 0.928
    • Malpractice GPCI 0.757 changed to 0.819

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $328.68changed to$350.34

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense RVU 6.09 changed to 6.68
    • Malpractice RVU 0.36 changed to 0.39
    • Practice expense GPCI 0.931 changed to 0.930
    • Malpractice GPCI 0.695 changed to 0.757

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $305.61changed to$328.68

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 5.42 changed to 6.09
    • Malpractice RVU 0.35 changed to 0.36

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $302.06changed to$305.61

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 5.32 changed to 5.42
    • Malpractice RVU 0.36 changed to 0.35
    • Malpractice GPCI 0.732 changed to 0.695

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $299.95changed to$302.06

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 5.27 changed to 5.32
    • Practice expense GPCI 0.930 changed to 0.931
    • Malpractice GPCI 0.768 changed to 0.732

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $300.37changed to$299.95

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 5.25 changed to 5.27

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $298.87changed to$300.37

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $294.41changed to$298.87

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 5.15 changed to 5.25
    • Malpractice RVU 0.32 changed to 0.36
    • Practice expense GPCI 0.929 changed to 0.930
    • Malpractice GPCI 0.732 changed to 0.768

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $292.04changed to$294.41

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 5.56 changed to 5.15
    • Malpractice RVU 0.33 changed to 0.32
    • Practice expense GPCI 0.927 changed to 0.929
    • Malpractice GPCI 0.695 changed to 0.732

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $292.04

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$342.13$141.75RVU26D
2026-07-01$342.13$141.75RVU26C
2026-04-01$342.13$141.75RVU26B
2026-01-01$342.13$141.75RVU26A
2025-10-01$332.70$155.08RVU25D
2025-07-01$332.70$155.08RVU25C
2025-04-01$332.70$155.08RVU25B
2025-01-01$332.70$155.08RVU25A
2024-10-01$362.50$158.13RVU24D
2024-07-01$362.50$158.13RVU24C
2024-04-01$362.50$158.13RVU24B
2024-03-09$362.50$158.13RVU24AR
2024-01-01$356.58$155.55RVU24A
2023-10-01$371.94$161.16RVU23D
2023-07-01$371.94$161.16RVU23C
2023-04-01$371.94$161.16RVU23B
2023-01-01$371.94$161.16RVU23A
2022-10-01$385.10$164.47RVU22D
2022-07-01$385.10$164.47RVU22C
2022-04-01$385.10$164.47RVU22B
2022-01-01$385.10$164.47RVU22A
2021-10-01$376.02$165.55RVU21D
2021-07-01$376.02$165.55RVU21C
2021-04-01$376.02$165.55RVU21B
2021-01-01$376.02$165.55RVU21A
2020-10-01$350.34$169.77RVU20D
2020-07-01$350.34$169.77RVU20C
2020-04-01$350.34$169.77RVU20B
2020-01-01$350.34$169.77RVU20A
2019-10-01$328.68$168.97RVU19D
2019-07-01$328.68$168.97RVU19C
2019-04-01$328.68$168.97RVU19B
2019-01-01$328.68$168.97RVU19A
2018-10-01$305.61$169.20RVU18D
2018-07-01$305.61$169.20RVU18C
2018-04-01$305.61$169.20RVU18B
2018-01-01$305.61$169.20RVU18AR1
2017-10-01$302.06$169.07RVU17D
2017-07-01$302.06$169.07RVU17C
2017-04-01$302.06$169.07RVU17B
2017-01-01$302.06$169.07RVU17A
2016-10-01$299.95$168.09RVU16D
2016-07-01$299.95$168.09RVU16C
2016-04-01$299.95$168.09RVU16B
2016-01-01$299.95$168.09RVU16A
2015-10-01$300.37$168.70RVU15D
2015-07-01$300.37$168.70RVU15C
2015-04-01$298.87$167.86RVU15B
2015-01-01$298.87$167.86RVU15A
2014-10-01$294.41$166.29RVU14D
2014-07-01$294.41$166.29RVU14C
2014-04-01$294.41$166.29RVU14B
2014-01-01$294.41$166.29RVU14A
2013-10-01$292.04$159.25RVU13D
2013-07-01$292.04$159.25RVU13C
2013-04-01$292.04$159.25RVU13B
2013-01-01$292.04$159.25RVU13AR

Price 52287 for an earlier date of service

Where the North Carolina rate applies

North Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 785 cities and communities in North Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Aberdeen
  • Advance
  • Ahoskie
  • Alamance
  • Albemarle
  • Alexis
  • Alliance
  • Altamahaw

Browse all communities in North Carolina

52287 billing questions

How is this different from cystoscopy with biopsy?

52287 reports injections intended to chemodenervate the bladder. A biopsy code is for sampling bladder tissue, not for the therapeutic injection.

Can the medication be reported separately?

When the practice supplies onabotulinumtoxinA, report the drug separately using the applicable drug code. The cystoscopic injection service is reported with 52287.

Should modifier 50 be appended?

No. The CMS bilateral adjustment does not apply, and modifier 50 is inappropriate for this service.

What happens when another related endoscopy is performed at the same session?

CMS endoscopy-family pricing applies when related endoscopies are performed together. Documentation should identify each distinct service performed.

What documentation supports 52287?

Document the bladder condition being treated, the chemodenervation agent and dose, the cystoscopic injection procedure, and the sites treated.

Can an assistant or co-surgeon be reported?

Medicare does not pay an assistant at surgery for this service. Co-surgeons and team surgery are not permitted.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 52287PPRRVU2026_Oct_nonQPP.csv, line 6,129 (RVU26D)
Geographic factors for North CarolinaGPCI2026.csv, line 83 (RVU26D)

Open CMS sourceHow we calculate rates

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