CPT code 58110: Endometrial biopsy, performed with colposcopy2026 Medicare rate & RVUs
Reports endometrial tissue sampling performed during a colposcopy when the uterine lining is evaluated separately from cervical or vaginal tissue.
Medicare pays $51.10 for 58110 nationally in the office and $35.40 in a hospital or facility. Local office rates run $45.82–$62.92.
Medicare rate · 58110
Endometrial biopsy, performed with colposcopy
- Work RVUs
- 0.75
- Total RVUs
- 1.53
- Global days
- ZZZ
National rate · 2026
$51.10
Office setting, before claim adjustments.
See every locality for 58110 →Billed by an NP, PA or therapist? →
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
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On this page 10 sections
What 58110 covers
This add-on represents a sample of the uterine lining obtained while the clinician performs a colposcopy. An OB-GYN or other qualified clinician may use an office endometrial sampler to investigate a uterine concern, such as abnormal bleeding, during a visit that also evaluates an abnormal cervical screening result. The endometrial specimen is distinct from tissue taken from the cervix or endocervical canal during colposcopy.
Report 58110 only with the primary colposcopy procedure; use 58100 for endometrial sampling performed without colposcopy. The record should identify the colposcopy and separately document endometrial sampling, its indication, method, and specimen. Cervical biopsy or endocervical curettage alone does not represent sampling of the uterine lining. CMS pays this add-on within the primary procedure's global period, so payment is associated with that primary service's global period.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
Where 58110 pays more and less
The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.
109 payment localities
$45.82 to $62.92
109 of 109 payment localities
58110 rates by state
Office rate range in each state. Select a state to see its payment localities.
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Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$45.82
$62.92
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $62.92 | 1 |
| AL | $46.40 | 1 |
| AR | $45.82 | 1 |
| AZ | $49.77 | 1 |
| CA | $51.41–$61.14 | 29 |
| CO | $51.75 | 1 |
| CT | $54.23 | 1 |
| DC | $56.79 | 1 |
| DE | $50.50 | 1 |
| FL | $52.51–$59.13 | 3 |
| GA | $49.69–$52.46 | 2 |
| GU | $52.06 | 1 |
| HI | $52.06 | 1 |
| IA | $46.47 | 1 |
| ID | $46.93 | 1 |
| IL | $51.88–$57.44 | 4 |
| IN | $47.14 | 1 |
| KS | $46.73 | 1 |
| KY | $48.33 | 1 |
| LA | $48.45–$50.48 | 2 |
| MA | $51.69–$55.76 | 2 |
| MD | $51.23–$56.79 | 3 |
| ME | $47.63–$49.19 | 2 |
| MI | $49.85–$53.56 | 2 |
| MN | $48.43 | 1 |
| MO | $48.03–$50.09 | 3 |
| MS | $46.91 | 1 |
| MT | $51.09 | 1 |
| NC | $47.98 | 1 |
| ND | $48.33 | 1 |
| NE | $46.55 | 1 |
| NH | $51.40 | 1 |
| NJ | $54.53–$56.42 | 2 |
| NM | $50.27 | 1 |
| NV | $50.34 | 1 |
| NY | $48.65–$60.75 | 5 |
| OH | $49.28 | 1 |
| OK | $47.77 | 1 |
| OR | $49.63–$52.68 | 2 |
| PA | $49.09–$53.33 | 2 |
| PR | $51.27 | 1 |
| RI | $51.78 | 1 |
| SC | $48.78 | 1 |
| SD | $48.00 | 1 |
| TN | $46.99 | 1 |
| TX | $48.85–$52.91 | 8 |
| UT | $49.34 | 1 |
| VA | $49.37–$56.79 | 2 |
| VI | $51.27 | 1 |
| VT | $48.58 | 1 |
| WA | $51.44–$56.35 | 2 |
| WI | $46.97 | 1 |
| WV | $50.32 | 1 |
| WY | $49.89 | 1 |
How the 58110 rate is calculated
Each of 58110’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 58110
RVUs × geographic indexes × conversion factor
Work0.75
0.75 RVUs× 1.000 GPCI
Practice expense0.64
0.64 RVUs× 1.000 GPCI
Malpractice0.14
0.14 RVUs× 1.000 GPCI
Adjusted RVUs
1.5300
Conversion factor
$33.4009
Medicare rate
$51.10
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
Payment rules and modifiers for 58110
The CMS indicators that decide how 58110 is paid alongside other services.
CMS payment indicators · 58110
Endometrial biopsy, performed with colposcopy
| Rule | CMS value | What it means |
|---|---|---|
| Global period | ZZZ | Add-on code: falls within the primary procedure’s global period. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 0 | Physician service: no professional/technical split. |
58110 compared with similar codes
Compare codes · National
4 codes, side by side
How to choose
- 58100Endometrial biopsyWithout cervical dilation
- 58100 describes endometrial sampling without colposcopy. Use 58110 when the endometrial sample is obtained in conjunction with a colposcopy.
- 57454Cervical colposcopyBiopsy and endocervical curettage
- 57454 covers colposcopy with cervical biopsy and endocervical curettage. It does not represent a separate sample from the uterine lining.
- 57456Cervical colposcopyEndocervical curettage
- 57456 covers colposcopy with endocervical curettage. 58110 represents endometrial sampling, a distinct specimen site.
58110 billing questions
When should 58110 be reported instead of 58100?
Report 58110 when endometrial sampling is performed in conjunction with a colposcopy. Use 58100 for endometrial sampling performed without colposcopy.
Does a cervical biopsy or endocervical curettage support 58110?
No. The add-on represents sampling of the uterine lining; cervical biopsy and endocervical curettage sample different sites.
Which primary procedure is reported with 58110?
Report it with the appropriate primary colposcopy procedure. The add-on is paid within that primary procedure's global period.
What documentation supports 58110?
Document the colposcopy and the separate endometrial sampling, including the indication, sampling method, and uterine lining specimen.
Can 58110 be reported for a stand-alone endometrial biopsy?
No. This is an add-on for endometrial sampling performed with colposcopy; 58100 is the relevant code for sampling without colposcopy.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
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