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CPT code 58110: Endometrial biopsy, performed with colposcopy2026 Medicare rate & RVUs in Mississippi

Reports endometrial tissue sampling performed during a colposcopy when the uterine lining is evaluated separately from cervical or vaginal tissue.

CMS RVU26DEffective Oct 1, 2026One payment locality671 Medicare services in 2024

In Mississippi, Medicare pays $46.91 for 58110 in the office and $33.40 when it’s performed in a hospital or facility.

$46.91Office (non-facility)
$33.40Hospital or facility
−8.2%vs the national office rate ($51.10)

Check a contract rate as a % of Medicare · 58110 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 58110 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Mississippi
  2. What 58110 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 58110 covers

This add-on represents a sample of the uterine lining obtained while the clinician performs a colposcopy. An OB-GYN or other qualified clinician may use an office endometrial sampler to investigate a uterine concern, such as abnormal bleeding, during a visit that also evaluates an abnormal cervical screening result. The endometrial specimen is distinct from tissue taken from the cervix or endocervical canal during colposcopy.

Report 58110 only with the primary colposcopy procedure; use 58100 for endometrial sampling performed without colposcopy. The record should identify the colposcopy and separately document endometrial sampling, its indication, method, and specimen. Cervical biopsy or endocervical curettage alone does not represent sampling of the uterine lining. CMS pays this add-on within the primary procedure's global period, so payment is associated with that primary service's global period.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Mississippi compares for 58110

Across 109 of 109 payment localities, the office rate for 58110 runs from $45.82 in Arkansas to $62.92 in Alaska. Mississippi pays $46.91. The RVUs are the same everywhere; the geographic indexes change the dollars.

58110 in Mississippi vs other payment areas
  1. Mississippi · this page$46.91
  2. Los Angeles, CA · California$54.47+$7.56
  3. Washington, DC area · District of Columbia$56.79+$9.88
  4. Miami, FL · Florida$59.13+$12.22
  5. Chicago, IL · Illinois$57.44+$10.53
  6. Manhattan, NY · New York$58.91+$12.00
  7. Alaska · Alaska$62.92+$16.01

Other areas in Mississippi first, then benchmark localities. Bars start at $0.

Every other payment area

58110 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$46.40$32.67
ArkansasArkansas$45.82$32.34
ArizonaArizona$49.77$34.56
Bakersfield, CACalifornia$51.80$34.60
Chico, CACalifornia$51.41$34.21
El Centro, CACalifornia$51.44$34.23
Fresno, CACalifornia$51.41$34.21
Hanford, CACalifornia$51.41$34.21

58110 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$45.82

$62.92

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
58110 office rate range by state
State / territoryOffice rate rangeLocalities
AK$62.921
AL$46.401
AR$45.821
AZ$49.771
CA$51.41–$61.1429
CO$51.751
CT$54.231
DC$56.791
DE$50.501
FL$52.51–$59.133
GA$49.69–$52.462
GU$52.061
HI$52.061
IA$46.471
ID$46.931
IL$51.88–$57.444
IN$47.141
KS$46.731
KY$48.331
LA$48.45–$50.482
MA$51.69–$55.762
MD$51.23–$56.793
ME$47.63–$49.192
MI$49.85–$53.562
MN$48.431
MO$48.03–$50.093
MS$46.911
MT$51.091
NC$47.981
ND$48.331
NE$46.551
NH$51.401
NJ$54.53–$56.422
NM$50.271
NV$50.341
NY$48.65–$60.755
OH$49.281
OK$47.771
OR$49.63–$52.682
PA$49.09–$53.332
PR$51.271
RI$51.781
SC$48.781
SD$48.001
TN$46.991
TX$48.85–$52.918
UT$49.341
VA$49.37–$56.792
VI$51.271
VT$48.581
WA$51.44–$56.352
WI$46.971
WV$50.321
WY$49.891

See 58110 in every payment locality

How the 58110 rate is calculated

Each of 58110’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 58110

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.75

0.75 RVUs× 1.000 GPCI

Practice expense0.64

0.64 RVUs× 1.000 GPCI

Malpractice0.14

0.14 RVUs× 1.000 GPCI

Adjusted RVUs

1.5300

Conversion factor

$33.4009

Medicare rate

$51.10

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Mississippi inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,517

Code
58110
Physician work
0.75
Practice expense
0.64
Malpractice
0.14

GPCI2026.csv

67

Locality
Mississippi
Physician work
1.000
Practice expense
0.861
Malpractice
0.739
Office calculation for 58110 in Mississippi
ComponentRVULocality factorAdjusted
Physician work0.75× 1.0000.7500
Practice expense0.64× 0.8610.5510
Malpractice0.14× 0.7390.1035
Total RVUs1.4045
Conversion factor× 33.4009

Office rate, Mississippi$46.91

Office: (0.75 × 1 + 0.64 × 0.861 + 0.14 × 0.739) × $33.4009 = $46.91

Facility: (0.75 × 1 + 0.17 × 0.861 + 0.14 × 0.739) × $33.4009 = $33.40

Open 58110 in the RVU calculator

Payment rules and modifiers for 58110

The CMS indicators that decide how 58110 is paid alongside other services.

CMS payment indicators · 58110

Endometrial biopsy, performed with colposcopy

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

Codes related to 58110

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 58110
CodeHow it relatesOffice range, Mississippi
Primary code
57452Colposcopy, cervix, no tissue samplingPrimary cervical colposcopy procedure that may accompany endometrial sampling.$113.85
57454Cervical colposcopy, biopsy and endocervical curettagePrimary colposcopy with cervical biopsy and endocervical curettage.$151.84
57455Cervical biopsy, colposcopy-guided biopsyPrimary colposcopy with cervical biopsy.$146.15
57456Cervical colposcopy, endocervical curettagePrimary colposcopy with endocervical curettage.$136.71
Used instead
58100Endometrial biopsy, without cervical dilationEndometrial sampling when performed without colposcopy.$89.17

How 58110 has changed in Mississippi

58110 · Office / nonfacility

$46.91

Effective 2026-10-01

The base rate is $2.24 higher than on 2025-10-01, moving from $44.67 to $46.91 (5.0%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $44.67changed to$46.91

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.77 changed to 0.75
    • Practice expense RVU 0.60 changed to 0.64
    • Malpractice RVU 0.13 changed to 0.14
    • Practice expense GPCI 0.852 changed to 0.861
    • Malpractice GPCI 0.768 changed to 0.739

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $46.25changed to$44.67

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 0.61 changed to 0.60

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $45.50changed to$46.25

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $46.24changed to$45.50

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.60 changed to 0.61
    • Malpractice RVU 0.12 changed to 0.13
    • Practice expense GPCI 0.847 changed to 0.852
    • Malpractice GPCI 0.720 changed to 0.768

  5. January 1, 2023

    RVU23A

    $46.62changed to$46.24

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.59 changed to 0.60
    • Practice expense GPCI 0.842 changed to 0.847
    • Malpractice GPCI 0.671 changed to 0.720

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $47.25changed to$46.62

    • Conversion factor 34.8931 changed to 34.6062
    • Malpractice RVU 0.13 changed to 0.12

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $47.65changed to$47.25

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 0.57 changed to 0.59
    • Malpractice RVU 0.12 changed to 0.13
    • Practice expense GPCI 0.856 changed to 0.842
    • Malpractice GPCI 0.521 changed to 0.671

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $46.96changed to$47.65

    • Conversion factor 36.0391 changed to 36.0896
    • Malpractice RVU 0.10 changed to 0.12
    • Practice expense GPCI 0.870 changed to 0.856
    • Malpractice GPCI 0.370 changed to 0.521

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $44.71changed to$46.96

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.50 changed to 0.57

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $44.78changed to$44.71

    • Conversion factor 35.8887 changed to 35.9996
    • Malpractice RVU 0.09 changed to 0.10
    • Practice expense GPCI 0.867 changed to 0.870
    • Malpractice GPCI 0.492 changed to 0.370

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $45.01changed to$44.78

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense GPCI 0.864 changed to 0.867
    • Malpractice GPCI 0.613 changed to 0.492

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $45.39changed to$45.01

    • Conversion factor 35.9335 changed to 35.8043
    • Malpractice RVU 0.10 changed to 0.09

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $45.17changed to$45.39

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $45.78changed to$45.17

    • Conversion factor 35.8228 changed to 35.7547
    • Malpractice RVU 0.11 changed to 0.10
    • Practice expense GPCI 0.865 changed to 0.864
    • Malpractice GPCI 0.687 changed to 0.613

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $45.22changed to$45.78

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 0.54 changed to 0.50
    • Malpractice RVU 0.12 changed to 0.11
    • Practice expense GPCI 0.866 changed to 0.865
    • Malpractice GPCI 0.761 changed to 0.687

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $45.22

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$46.91$33.40RVU26D
2026-07-01$46.91$33.40RVU26C
2026-04-01$46.91$33.40RVU26B
2026-01-01$46.91$33.40RVU26A
2025-10-01$44.67$36.68RVU25D
2025-07-01$44.67$36.68RVU25C
2025-04-01$44.67$36.68RVU25B
2025-01-01$44.67$36.68RVU25A
2024-10-01$46.25$37.46RVU24D
2024-07-01$46.25$37.46RVU24C
2024-04-01$46.25$37.46RVU24B
2024-03-09$46.25$37.46RVU24AR
2024-01-01$45.50$36.85RVU24A
2023-10-01$46.24$37.63RVU23D
2023-07-01$46.24$37.63RVU23C
2023-04-01$46.24$37.63RVU23B
2023-01-01$46.24$37.63RVU23A
2022-10-01$46.62$38.17RVU22D
2022-07-01$46.62$38.17RVU22C
2022-04-01$46.62$38.17RVU22B
2022-01-01$46.62$38.17RVU22A
2021-10-01$47.25$38.73RVU21D
2021-07-01$47.25$38.73RVU21C
2021-04-01$47.25$38.73RVU21B
2021-01-01$47.25$38.73RVU21A
2020-10-01$47.65$39.31RVU20D
2020-07-01$47.65$39.31RVU20C
2020-04-01$47.65$39.31RVU20B
2020-01-01$47.65$39.31RVU20A
2019-10-01$46.96$38.49RVU19D
2019-07-01$46.96$38.49RVU19C
2019-04-01$46.96$38.49RVU19B
2019-01-01$46.96$38.49RVU19A
2018-10-01$44.71$38.45RVU18D
2018-07-01$44.71$38.45RVU18C
2018-04-01$44.71$38.45RVU18B
2018-01-01$44.71$38.45RVU18AR1
2017-10-01$44.78$38.87RVU17D
2017-07-01$44.78$38.87RVU17C
2017-04-01$44.78$38.87RVU17B
2017-01-01$44.78$38.87RVU17A
2016-10-01$45.01$38.83RVU16D
2016-07-01$45.01$38.83RVU16C
2016-04-01$45.01$38.83RVU16B
2016-01-01$45.01$38.83RVU16A
2015-10-01$45.39$39.50RVU15D
2015-07-01$45.39$39.50RVU15C
2015-04-01$45.17$39.30RVU15B
2015-01-01$45.17$39.30RVU15A
2014-10-01$45.78$39.90RVU14D
2014-07-01$45.78$39.90RVU14C
2014-04-01$45.78$39.90RVU14B
2014-01-01$45.78$39.90RVU14A
2013-10-01$45.22$39.03RVU13D
2013-07-01$45.22$39.03RVU13C
2013-04-01$45.22$39.03RVU13B
2013-01-01$45.22$39.03RVU13AR

Price 58110 for an earlier date of service

Where the Mississippi rate applies

Mississippi is a Medicare payment area, not a city. Our Census mapping connects it to 427 cities and communities in Mississippi. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Aberdeen
  • Ackerman
  • Agricola
  • Alcorn State University
  • Algoma
  • Alligator
  • Amory

Browse all communities in Mississippi

58110 billing questions

When should 58110 be reported instead of 58100?

Report 58110 when endometrial sampling is performed in conjunction with a colposcopy. Use 58100 for endometrial sampling performed without colposcopy.

Does a cervical biopsy or endocervical curettage support 58110?

No. The add-on represents sampling of the uterine lining; cervical biopsy and endocervical curettage sample different sites.

Which primary procedure is reported with 58110?

Report it with the appropriate primary colposcopy procedure. The add-on is paid within that primary procedure's global period.

What documentation supports 58110?

Document the colposcopy and the separate endometrial sampling, including the indication, sampling method, and uterine lining specimen.

Can 58110 be reported for a stand-alone endometrial biopsy?

No. This is an add-on for endometrial sampling performed with colposcopy; 58100 is the relevant code for sampling without colposcopy.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 58110PPRRVU2026_Oct_nonQPP.csv, line 6,517 (RVU26D)
Geographic factors for MississippiGPCI2026.csv, line 67 (RVU26D)

Open CMS sourceHow we calculate rates

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