CPT code 58110: Endometrial biopsy, performed with colposcopy2026 Medicare rate & RVUs in South Carolina

Reports endometrial tissue sampling performed during a colposcopy when the uterine lining is evaluated separately from cervical or vaginal tissue.

CMS RVU26DEffective Oct 1, 2026One payment locality671 Medicare services in 2024

In South Carolina, Medicare pays $48.78 for 58110 in the office and $34.27 when it’s performed in a hospital or facility.

$48.78Office (non-facility)
$34.27Hospital or facility
−4.5%vs the national office rate ($51.10)

Check a contract rate as a % of Medicare · 58110 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 58110 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Carolina
  2. What 58110 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 58110 covers

This add-on represents a sample of the uterine lining obtained while the clinician performs a colposcopy. An OB-GYN or other qualified clinician may use an office endometrial sampler to investigate a uterine concern, such as abnormal bleeding, during a visit that also evaluates an abnormal cervical screening result. The endometrial specimen is distinct from tissue taken from the cervix or endocervical canal during colposcopy.

Report 58110 only with the primary colposcopy procedure; use 58100 for endometrial sampling performed without colposcopy. The record should identify the colposcopy and separately document endometrial sampling, its indication, method, and specimen. Cervical biopsy or endocervical curettage alone does not represent sampling of the uterine lining. CMS pays this add-on within the primary procedure's global period, so payment is associated with that primary service's global period.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Carolina compares for 58110

Across 109 of 109 payment localities, the office rate for 58110 runs from $45.82 in Arkansas to $62.92 in Alaska. South Carolina pays $48.78. The RVUs are the same everywhere; the geographic indexes change the dollars.

58110 in South Carolina vs other payment areas
  1. South Carolina · this page$48.78
  2. Los Angeles, CA · California$54.47+$5.69
  3. Washington, DC area · District of Columbia$56.79+$8.01
  4. Miami, FL · Florida$59.13+$10.35
  5. Chicago, IL · Illinois$57.44+$8.66
  6. Manhattan, NY · New York$58.91+$10.13
  7. Alaska · Alaska$62.92+$14.14

Other areas in South Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

58110 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$46.40$32.67
ArkansasArkansas$45.82$32.34
ArizonaArizona$49.77$34.56
Bakersfield, CACalifornia$51.80$34.60
Chico, CACalifornia$51.41$34.21
El Centro, CACalifornia$51.44$34.23
Fresno, CACalifornia$51.41$34.21
Hanford, CACalifornia$51.41$34.21

58110 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$45.82

$62.92

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
58110 office rate range by state
State / territoryOffice rate rangeLocalities
AK$62.921
AL$46.401
AR$45.821
AZ$49.771
CA$51.41–$61.1429
CO$51.751
CT$54.231
DC$56.791
DE$50.501
FL$52.51–$59.133
GA$49.69–$52.462
GU$52.061
HI$52.061
IA$46.471
ID$46.931
IL$51.88–$57.444
IN$47.141
KS$46.731
KY$48.331
LA$48.45–$50.482
MA$51.69–$55.762
MD$51.23–$56.793
ME$47.63–$49.192
MI$49.85–$53.562
MN$48.431
MO$48.03–$50.093
MS$46.911
MT$51.091
NC$47.981
ND$48.331
NE$46.551
NH$51.401
NJ$54.53–$56.422
NM$50.271
NV$50.341
NY$48.65–$60.755
OH$49.281
OK$47.771
OR$49.63–$52.682
PA$49.09–$53.332
PR$51.271
RI$51.781
SC$48.781
SD$48.001
TN$46.991
TX$48.85–$52.918
UT$49.341
VA$49.37–$56.792
VI$51.271
VT$48.581
WA$51.44–$56.352
WI$46.971
WV$50.321
WY$49.891

See 58110 in every payment locality

How the 58110 rate is calculated

Each of 58110’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 58110

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.75

0.75 RVUs× 1.000 GPCI

Practice expense0.64

0.64 RVUs× 1.000 GPCI

Malpractice0.14

0.14 RVUs× 1.000 GPCI

Adjusted RVUs

1.5300

Conversion factor

$33.4009

Medicare rate

$51.10

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

6,517

Code
58110
Physician work
0.75
Practice expense
0.64
Malpractice
0.14

GPCI2026.csv

93

Locality
South Carolina
Physician work
1.000
Practice expense
0.924
Malpractice
0.850
Office calculation for 58110 in South Carolina
ComponentRVULocality factorAdjusted
Physician work0.75× 1.0000.7500
Practice expense0.64× 0.9240.5914
Malpractice0.14× 0.8500.1190
Total RVUs1.4604
Conversion factor× 33.4009

Office rate, South Carolina$48.78

Office: (0.75 × 1 + 0.64 × 0.924 + 0.14 × 0.85) × $33.4009 = $48.78

Facility: (0.75 × 1 + 0.17 × 0.924 + 0.14 × 0.85) × $33.4009 = $34.27

Open 58110 in the RVU calculator

Payment rules and modifiers for 58110

The CMS indicators that decide how 58110 is paid alongside other services.

CMS payment indicators · 58110

Endometrial biopsy, performed with colposcopy

RuleCMS valueWhat it means
Global periodZZZAdd-on code: falls within the primary procedure’s global period.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical0Physician service: no professional/technical split.

How 58110 has changed in South Carolina

58110 · Office / nonfacility

$48.78

Effective 2026-10-01

The base rate is $2.72 higher than on 2025-10-01, moving from $46.06 to $48.78 (5.9%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $46.06changed to$48.78

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.77 changed to 0.75
    • Practice expense RVU 0.60 changed to 0.64
    • Malpractice RVU 0.13 changed to 0.14
    • Practice expense GPCI 0.913 changed to 0.924
    • Malpractice GPCI 0.817 changed to 0.850

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $47.71changed to$46.06

    • Conversion factor 33.2875 changed to 32.3465
    • Practice expense RVU 0.61 changed to 0.60

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $46.93changed to$47.71

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $47.63changed to$46.93

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.60 changed to 0.61
    • Malpractice RVU 0.12 changed to 0.13
    • Practice expense GPCI 0.908 changed to 0.913
    • Malpractice GPCI 0.756 changed to 0.817
  5. January 1, 2023

    RVU23A

    $47.97changed to$47.63

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.59 changed to 0.60
    • Practice expense GPCI 0.903 changed to 0.908
    • Malpractice GPCI 0.695 changed to 0.756

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $48.61changed to$47.97

    • Conversion factor 34.8931 changed to 34.6062
    • Malpractice RVU 0.13 changed to 0.12

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $49.15changed to$48.61

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 0.57 changed to 0.59
    • Malpractice RVU 0.12 changed to 0.13
    • Practice expense GPCI 0.907 changed to 0.903
    • Malpractice GPCI 0.624 changed to 0.695

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $48.48changed to$49.15

    • Conversion factor 36.0391 changed to 36.0896
    • Malpractice RVU 0.10 changed to 0.12
    • Practice expense GPCI 0.912 changed to 0.907
    • Malpractice GPCI 0.553 changed to 0.624

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $46.13changed to$48.48

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.50 changed to 0.57

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $46.05changed to$46.13

    • Conversion factor 35.8887 changed to 35.9996
    • Malpractice RVU 0.09 changed to 0.10
    • Malpractice GPCI 0.634 changed to 0.553

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $46.20changed to$46.05

    • Conversion factor 35.8043 changed to 35.8887
    • Malpractice GPCI 0.715 changed to 0.634

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $46.62changed to$46.20

    • Conversion factor 35.9335 changed to 35.8043
    • Malpractice RVU 0.10 changed to 0.09

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $46.39changed to$46.62

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $46.34changed to$46.39

    • Conversion factor 35.8228 changed to 35.7547
    • Malpractice RVU 0.11 changed to 0.10
    • Practice expense GPCI 0.911 changed to 0.912
    • Malpractice GPCI 0.618 changed to 0.715

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $45.02changed to$46.34

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 0.54 changed to 0.50
    • Malpractice RVU 0.12 changed to 0.11
    • Practice expense GPCI 0.909 changed to 0.911
    • Malpractice GPCI 0.520 changed to 0.618

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $45.02

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$48.78$34.27RVU26D
2026-07-01$48.78$34.27RVU26C
2026-04-01$48.78$34.27RVU26B
2026-01-01$48.78$34.27RVU26A
2025-10-01$46.06$37.50RVU25D
2025-07-01$46.06$37.50RVU25C
2025-04-01$46.06$37.50RVU25B
2025-01-01$46.06$37.50RVU25A
2024-10-01$47.71$38.28RVU24D
2024-07-01$47.71$38.28RVU24C
2024-04-01$47.71$38.28RVU24B
2024-03-09$47.71$38.28RVU24AR
2024-01-01$46.93$37.66RVU24A
2023-10-01$47.63$38.40RVU23D
2023-07-01$47.63$38.40RVU23C
2023-04-01$47.63$38.40RVU23B
2023-01-01$47.63$38.40RVU23A
2022-10-01$47.97$38.91RVU22D
2022-07-01$47.97$38.91RVU22C
2022-04-01$47.97$38.91RVU22B
2022-01-01$47.97$38.91RVU22A
2021-10-01$48.61$39.47RVU21D
2021-07-01$48.61$39.47RVU21C
2021-04-01$48.61$39.47RVU21B
2021-01-01$48.61$39.47RVU21A
2020-10-01$49.15$40.31RVU20D
2020-07-01$49.15$40.31RVU20C
2020-04-01$49.15$40.31RVU20B
2020-01-01$49.15$40.31RVU20A
2019-10-01$48.48$39.60RVU19D
2019-07-01$48.48$39.60RVU19C
2019-04-01$48.48$39.60RVU19B
2019-01-01$48.48$39.60RVU19A
2018-10-01$46.13$39.56RVU18D
2018-07-01$46.13$39.56RVU18C
2018-04-01$46.13$39.56RVU18B
2018-01-01$46.13$39.56RVU18AR1
2017-10-01$46.05$39.83RVU17D
2017-07-01$46.05$39.83RVU17C
2017-04-01$46.05$39.83RVU17B
2017-01-01$46.05$39.83RVU17A
2016-10-01$46.20$39.67RVU16D
2016-07-01$46.20$39.67RVU16C
2016-04-01$46.20$39.67RVU16B
2016-01-01$46.20$39.67RVU16A
2015-10-01$46.62$40.40RVU15D
2015-07-01$46.62$40.40RVU15C
2015-04-01$46.39$40.20RVU15B
2015-01-01$46.39$40.20RVU15A
2014-10-01$46.34$40.14RVU14D
2014-07-01$46.34$40.14RVU14C
2014-04-01$46.34$40.14RVU14B
2014-01-01$46.34$40.14RVU14A
2013-10-01$45.02$38.53RVU13D
2013-07-01$45.02$38.53RVU13C
2013-04-01$45.02$38.53RVU13B
2013-01-01$45.02$38.53RVU13AR

Price 58110 for an earlier date of service

Where the South Carolina rate applies

South Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 475 cities and communities in South Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Abney Crossroads
  • Adams Run
  • Aiken
  • Alcolu
  • Allendale
  • Anderson
  • Andrews

Browse all communities in South Carolina

58110 billing questions

When should 58110 be reported instead of 58100?

Report 58110 when endometrial sampling is performed in conjunction with a colposcopy. Use 58100 for endometrial sampling performed without colposcopy.

Does a cervical biopsy or endocervical curettage support 58110?

No. The add-on represents sampling of the uterine lining; cervical biopsy and endocervical curettage sample different sites.

Which primary procedure is reported with 58110?

Report it with the appropriate primary colposcopy procedure. The add-on is paid within that primary procedure's global period.

What documentation supports 58110?

Document the colposcopy and the separate endometrial sampling, including the indication, sampling method, and uterine lining specimen.

Can 58110 be reported for a stand-alone endometrial biopsy?

No. This is an add-on for endometrial sampling performed with colposcopy; 58100 is the relevant code for sampling without colposcopy.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 58110PPRRVU2026_Oct_nonQPP.csv, line 6,517 (RVU26D)
Geographic factors for South CarolinaGPCI2026.csv, line 93 (RVU26D)

Open CMS sourceHow we calculate rates

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