CPT code 88188: Flow cytometry, 9–15 markers2026 Medicare rate & RVUs

Reports a pathologist’s interpretation of flow cytometry findings when the analysis includes 9–15 markers, commonly for suspected hematologic malignancy.

CMS RVU26DEffective Oct 1, 2026109 payment localities44.9K Medicare services in 2024

Medicare pays $58.45 for 88188 nationally in the office and $58.45 in a hospital or facility. Local office rates run $55.03–$78.22.

Medicare rate · 88188

Flow cytometry, 9–15 markers

Office or facility?

Work RVUs
1.17
Total RVUs
1.75
Global days
XXX

National rate · 2026

$58.45

Office setting, before claim adjustments.

See every locality for 88188 →Billed by an NP, PA or therapist? →

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

Your location

Medicare pays by the payment locality where the service is performed.

On this page 10 sections
  1. Medicare rate
  2. What 88188 covers
  3. By payment locality
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Similar codes
  8. Related codes
  9. Billing questions
  10. Sources

What 88188 covers

This service is the professional interpretation and written report of flow cytometry findings from a panel of 9–15 markers. A pathologist or other qualified laboratory professional may evaluate results from peripheral blood, bone marrow, lymph node, or fluid specimens when assessing suspected leukemia, lymphoma, or another hematologic disorder. The report interprets the cell populations and marker pattern in the clinical context; it is not the laboratory work that processes and analyzes the specimen.

Select this code according to the number of markers included in the interpretation: 9–15. The record should support the specimen examined, markers assessed, findings, and resulting interpretation. Report the professional service separately from the applicable technical flow cytometry services; the technical portion is covered by separate codes. This code represents interpretation and reporting only.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

Where 88188 pays more and less

The same RVUs, adjusted for each area’s costs. Open a locality for its calculation, history and nearby areas.

109 payment localities

$55.03 to $78.22

$55.03$66.63$78.22
One dot per payment locality, office / nonfacility. Hover a dot to see the locality; select it to open that rate.

109 of 109 payment localities

88188 office and facility rates by payment locality
Payment localityOfficeFacility
Alabama$55.41$55.41
Alaska$78.22$78.22
Arizona$57.62$57.62
Arkansas$55.03$55.03
Atlanta, GA$59.25$59.25
Austin, TX$59.31$59.31
Bakersfield, CA$60.08$60.08
Baltimore area, MD$60.82$60.82
Beaumont, TX$56.75$56.75
Brazoria, TX$58.17$58.17

88188 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$55.03

$78.22

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88188 office rate range by state
State / territoryOffice rate rangeLocalities
AK$78.221
AL$55.411
AR$55.031
AZ$57.621
CA$59.85–$69.5029
CO$59.591
CT$60.991
DC$63.881
DE$58.241
FL$58.70–$62.233
GA$56.96–$59.252
GU$59.991
HI$59.991
IA$55.771
ID$56.011
IL$58.07–$61.414
IN$56.151
KS$55.791
KY$56.351
LA$56.37–$57.702
MA$59.59–$63.202
MD$58.89–$63.883
ME$56.30–$57.562
MI$57.20–$59.222
MN$57.541
MO$56.00–$57.623
MS$55.511
MT$58.451
NC$56.561
ND$57.261
NE$55.871
NH$58.911
NJ$61.81–$63.832
NM$57.411
NV$58.131
NY$56.99–$65.955
OH$56.961
OK$56.151
OR$57.79–$60.492
PA$56.92–$60.252
PR$58.611
RI$59.551
SC$56.831
SD$57.121
TN$55.941
TX$56.75–$59.408
UT$57.211
VA$57.57–$63.882
VI$58.611
VT$57.291
WA$59.40–$63.982
WI$56.341
WV$57.041
WY$57.931

How the 88188 rate is calculated

Each of 88188’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88188

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.17

1.17 RVUs× 1.000 GPCI

Practice expense0.52

0.52 RVUs× 1.000 GPCI

Malpractice0.06

0.06 RVUs× 1.000 GPCI

Adjusted RVUs

1.7500

Conversion factor

$33.4009

Medicare rate

$58.45

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

Payment rules and modifiers for 88188

The CMS indicators that decide how 88188 is paid alongside other services.

CMS payment indicators · 88188

Flow cytometry, 9–15 markers

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical2Professional component only.

88188 compared with similar codes

Compare codes · National

4 codes, side by side

Office or facility?

  • 88188

    Flow cytometry, 9–15 markers1.17 wRVU

    $58.45

  • 88187

    Flow cytometry, 2–8 marker interpretation0.72 wRVU

    $35.07−$23.38

  • 88189

    Flow cytometry, 16 or more markers1.66 wRVU

    $79.16+$20.71

  • 88184

    Flow cytometry, first marker, technical component0 wRVU

    $81.16+$22.71

How to choose

88187Flow cytometry2–8 marker interpretation
Use 88187 when the professional interpretation covers 2–8 markers; 88188 is for 9–15.
88189Flow cytometry16 or more markers
Use 88189 when the professional interpretation covers 16 or more markers; 88188 is for 9–15.
88184Flow cytometryFirst marker, technical component
88184 represents technical flow cytometry work for the first marker. 88188 represents professional interpretation and reporting for a 9–15-marker panel.

88188 billing questions

How is 88188 selected over 88187 or 88189?

Choose 88188 when the interpretation covers 9–15 markers. The neighboring interpretation codes represent 2–8 markers and 16 or more markers, respectively.

Does 88188 include specimen processing and flow analysis?

No. It covers the professional interpretation and report; separate codes represent the technical flow cytometry work.

Should modifier 26 be appended?

No. 88188 is a professional-component-only code for interpretation and reporting.

Is 88188 reported once per marker?

No. Select the interpretation code based on the total marker count; 88188 represents a 9–15-marker analysis, not an individual marker.

What documentation supports reporting 88188?

Document the specimen, the markers assessed, the interpreted findings, and the report. The documentation should support that the interpreted panel falls within the 9–15-marker range.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88188PPRRVU2026_Oct_nonQPP.csv, line 11,165 (RVU26D)

Open CMS sourceHow we calculate rates

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