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CPT code 88188: Flow cytometry, 9–15 markers2026 Medicare rate & RVUs in South Carolina

Reports a pathologist’s interpretation of flow cytometry findings when the analysis includes 9–15 markers, commonly for suspected hematologic malignancy.

CMS RVU26DEffective Oct 1, 2026One payment locality44.9K Medicare services in 2024

In South Carolina, Medicare pays $56.83 for 88188 in the office and $56.83 when it’s performed in a hospital or facility.

$56.83Office (non-facility)
$56.83Hospital or facility
−2.8%vs the national office rate ($58.45)

Check a contract rate as a % of Medicare · 88188 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88188 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in South Carolina
  2. What 88188 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88188 covers

This service is the professional interpretation and written report of flow cytometry findings from a panel of 9–15 markers. A pathologist or other qualified laboratory professional may evaluate results from peripheral blood, bone marrow, lymph node, or fluid specimens when assessing suspected leukemia, lymphoma, or another hematologic disorder. The report interprets the cell populations and marker pattern in the clinical context; it is not the laboratory work that processes and analyzes the specimen.

Select this code according to the number of markers included in the interpretation: 9–15. The record should support the specimen examined, markers assessed, findings, and resulting interpretation. Report the professional service separately from the applicable technical flow cytometry services; the technical portion is covered by separate codes. This code represents interpretation and reporting only.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Carolina compares for 88188

Across 109 of 109 payment localities, the office rate for 88188 runs from $55.03 in Arkansas to $78.22 in Alaska. South Carolina pays $56.83. The RVUs are the same everywhere; the geographic indexes change the dollars.

88188 in South Carolina vs other payment areas
  1. South Carolina · this page$56.83
  2. Los Angeles, CA · California$62.56+$5.73
  3. Washington, DC area · District of Columbia$63.88+$7.05
  4. Miami, FL · Florida$62.23+$5.40
  5. Chicago, IL · Illinois$61.41+$4.58
  6. Manhattan, NY · New York$64.94+$8.11
  7. Alaska · Alaska$78.22+$21.39

Other areas in South Carolina first, then benchmark localities. Bars start at $0.

Every other payment area

88188 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$55.41$55.41
ArkansasArkansas$55.03$55.03
ArizonaArizona$57.62$57.62
Bakersfield, CACalifornia$60.08$60.08
Chico, CACalifornia$59.85$59.85
El Centro, CACalifornia$59.86$59.86
Fresno, CACalifornia$59.85$59.85
Hanford, CACalifornia$59.85$59.85

88188 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$55.03

$78.22

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88188 office rate range by state
State / territoryOffice rate rangeLocalities
AK$78.221
AL$55.411
AR$55.031
AZ$57.621
CA$59.85–$69.5029
CO$59.591
CT$60.991
DC$63.881
DE$58.241
FL$58.70–$62.233
GA$56.96–$59.252
GU$59.991
HI$59.991
IA$55.771
ID$56.011
IL$58.07–$61.414
IN$56.151
KS$55.791
KY$56.351
LA$56.37–$57.702
MA$59.59–$63.202
MD$58.89–$63.883
ME$56.30–$57.562
MI$57.20–$59.222
MN$57.541
MO$56.00–$57.623
MS$55.511
MT$58.451
NC$56.561
ND$57.261
NE$55.871
NH$58.911
NJ$61.81–$63.832
NM$57.411
NV$58.131
NY$56.99–$65.955
OH$56.961
OK$56.151
OR$57.79–$60.492
PA$56.92–$60.252
PR$58.611
RI$59.551
SC$56.831
SD$57.121
TN$55.941
TX$56.75–$59.408
UT$57.211
VA$57.57–$63.882
VI$58.611
VT$57.291
WA$59.40–$63.982
WI$56.341
WV$57.041
WY$57.931

See 88188 in every payment locality

How the 88188 rate is calculated

Each of 88188’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88188

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.17

1.17 RVUs× 1.000 GPCI

Practice expense0.52

0.52 RVUs× 1.000 GPCI

Malpractice0.06

0.06 RVUs× 1.000 GPCI

Adjusted RVUs

1.7500

Conversion factor

$33.4009

Medicare rate

$58.45

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact South Carolina inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,165

Code
88188
Physician work
1.17
Practice expense
0.52
Malpractice
0.06

GPCI2026.csv

93

Locality
South Carolina
Physician work
1.000
Practice expense
0.924
Malpractice
0.850
Office calculation for 88188 in South Carolina
ComponentRVULocality factorAdjusted
Physician work1.17× 1.0001.1700
Practice expense0.52× 0.9240.4805
Malpractice0.06× 0.8500.0510
Total RVUs1.7015
Conversion factor× 33.4009

Office rate, South Carolina$56.83

Office: (1.17 × 1 + 0.52 × 0.924 + 0.06 × 0.85) × $33.4009 = $56.83

Facility: (1.17 × 1 + 0.52 × 0.924 + 0.06 × 0.85) × $33.4009 = $56.83

Open 88188 in the RVU calculator

Payment rules and modifiers for 88188

The CMS indicators that decide how 88188 is paid alongside other services.

CMS payment indicators · 88188

Flow cytometry, 9–15 markers

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical2Professional component only.

Codes related to 88188

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 88188
CodeHow it relatesOffice range, South Carolina
Often billed with
88184Flow cytometry, first marker, technical componentTechnical flow cytometry service for the first marker may accompany the professional interpretation.$74.95
88185Flow cytometry add-on, technical work, each additional markerTechnical flow cytometry service for additional markers may accompany the professional interpretation.$21.30
Same family
88187Flow cytometry, 2–8 marker interpretationProfessional interpretation for a smaller panel of 2–8 markers.$34.16
88189Flow cytometry, 16 or more markersProfessional interpretation for a panel of 16 or more markers.$77.18

How 88188 has changed in South Carolina

88188 · Office / nonfacility

$56.83

Effective 2026-10-01

The base rate is $0.45 higher than on 2025-10-01, moving from $56.38 to $56.83 (0.8%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $56.38changed to$56.83

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.20 changed to 1.17
    • Practice expense RVU 0.55 changed to 0.52
    • Malpractice RVU 0.05 changed to 0.06
    • Practice expense GPCI 0.913 changed to 0.924
    • Malpractice GPCI 0.817 changed to 0.850

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $58.29changed to$56.38

    • Conversion factor 33.2875 changed to 32.3465
    • Malpractice RVU 0.06 changed to 0.05

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $57.34changed to$58.29

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $59.43changed to$57.34

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.56 changed to 0.55
    • Practice expense GPCI 0.908 changed to 0.913
    • Malpractice GPCI 0.756 changed to 0.817

  5. January 1, 2023

    RVU23A

    $60.33changed to$59.43

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.54 changed to 0.56
    • Malpractice RVU 0.08 changed to 0.06
    • Practice expense GPCI 0.903 changed to 0.908
    • Malpractice GPCI 0.695 changed to 0.756

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $60.41changed to$60.33

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 0.55 changed to 0.54
    • Malpractice RVU 0.05 changed to 0.08

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $63.32changed to$60.41

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 0.57 changed to 0.55
    • Malpractice RVU 0.06 changed to 0.05
    • Practice expense GPCI 0.907 changed to 0.903
    • Malpractice GPCI 0.624 changed to 0.695

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $63.18changed to$63.32

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense GPCI 0.912 changed to 0.907
    • Malpractice GPCI 0.553 changed to 0.624

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $63.76changed to$63.18

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.59 changed to 0.57

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $71.93changed to$63.76

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 0.84 changed to 0.59
    • Malpractice GPCI 0.634 changed to 0.553

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $89.59changed to$71.93

    • Conversion factor 35.8043 changed to 35.8887
    • Work RVU 1.69 changed to 1.20
    • Practice expense RVU 0.82 changed to 0.84
    • Malpractice RVU 0.09 changed to 0.06
    • Malpractice GPCI 0.715 changed to 0.634

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $88.93changed to$89.59

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 0.79 changed to 0.82

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $88.49changed to$88.93

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $86.58changed to$88.49

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 0.73 changed to 0.79
    • Malpractice RVU 0.10 changed to 0.09
    • Practice expense GPCI 0.911 changed to 0.912
    • Malpractice GPCI 0.618 changed to 0.715

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $83.70changed to$86.58

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 0.79 changed to 0.73
    • Practice expense GPCI 0.909 changed to 0.911
    • Malpractice GPCI 0.520 changed to 0.618

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $83.70

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$56.83$56.83RVU26D
2026-07-01$56.83$56.83RVU26C
2026-04-01$56.83$56.83RVU26B
2026-01-01$56.83$56.83RVU26A
2025-10-01$56.38$56.38RVU25D
2025-07-01$56.38$56.38RVU25C
2025-04-01$56.38$56.38RVU25B
2025-01-01$56.38$56.38RVU25A
2024-10-01$58.29$58.29RVU24D
2024-07-01$58.29$58.29RVU24C
2024-04-01$58.29$58.29RVU24B
2024-03-09$58.29$58.29RVU24AR
2024-01-01$57.34$57.34RVU24A
2023-10-01$59.43$59.43RVU23D
2023-07-01$59.43$59.43RVU23C
2023-04-01$59.43$59.43RVU23B
2023-01-01$59.43$59.43RVU23A
2022-10-01$60.33$60.33RVU22D
2022-07-01$60.33$60.33RVU22C
2022-04-01$60.33$60.33RVU22B
2022-01-01$60.33$60.33RVU22A
2021-10-01$60.41$60.41RVU21D
2021-07-01$60.41$60.41RVU21C
2021-04-01$60.41$60.41RVU21B
2021-01-01$60.41$60.41RVU21A
2020-10-01$63.32$63.32RVU20D
2020-07-01$63.32$63.32RVU20C
2020-04-01$63.32$63.32RVU20B
2020-01-01$63.32$63.32RVU20A
2019-10-01$63.18$63.18RVU19D
2019-07-01$63.18$63.18RVU19C
2019-04-01$63.18$63.18RVU19B
2019-01-01$63.18$63.18RVU19A
2018-10-01$63.76$63.76RVU18D
2018-07-01$63.76$63.76RVU18C
2018-04-01$63.76$63.76RVU18B
2018-01-01$63.76$63.76RVU18AR1
2017-10-01$71.93$71.93RVU17D
2017-07-01$71.93$71.93RVU17C
2017-04-01$71.93$71.93RVU17B
2017-01-01$71.93$71.93RVU17A
2016-10-01$89.59$89.59RVU16D
2016-07-01$89.59$89.59RVU16C
2016-04-01$89.59$89.59RVU16B
2016-01-01$89.59$89.59RVU16A
2015-10-01$88.93$88.93RVU15D
2015-07-01$88.93$88.93RVU15C
2015-04-01$88.49$88.49RVU15B
2015-01-01$88.49$88.49RVU15A
2014-10-01$86.58$86.58RVU14D
2014-07-01$86.58$86.58RVU14C
2014-04-01$86.58$86.58RVU14B
2014-01-01$86.58$86.58RVU14A
2013-10-01$83.70$83.70RVU13D
2013-07-01$83.70$83.70RVU13C
2013-04-01$83.70$83.70RVU13B
2013-01-01$83.70$83.70RVU13AR

Price 88188 for an earlier date of service

Where the South Carolina rate applies

South Carolina is a Medicare payment area, not a city. Our Census mapping connects it to 475 cities and communities in South Carolina. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Abney Crossroads
  • Adams Run
  • Aiken
  • Alcolu
  • Allendale
  • Anderson
  • Andrews

Browse all communities in South Carolina

88188 billing questions

How is 88188 selected over 88187 or 88189?

Choose 88188 when the interpretation covers 9–15 markers. The neighboring interpretation codes represent 2–8 markers and 16 or more markers, respectively.

Does 88188 include specimen processing and flow analysis?

No. It covers the professional interpretation and report; separate codes represent the technical flow cytometry work.

Should modifier 26 be appended?

No. 88188 is a professional-component-only code for interpretation and reporting.

Is 88188 reported once per marker?

No. Select the interpretation code based on the total marker count; 88188 represents a 9–15-marker analysis, not an individual marker.

What documentation supports reporting 88188?

Document the specimen, the markers assessed, the interpreted findings, and the report. The documentation should support that the interpreted panel falls within the 9–15-marker range.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88188PPRRVU2026_Oct_nonQPP.csv, line 11,165 (RVU26D)
Geographic factors for South CarolinaGPCI2026.csv, line 93 (RVU26D)

Open CMS sourceHow we calculate rates

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