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CPT code 88188: Flow cytometry, 9–15 markers2026 Medicare rate & RVUs in Mississippi

Reports a pathologist’s interpretation of flow cytometry findings when the analysis includes 9–15 markers, commonly for suspected hematologic malignancy.

CMS RVU26DEffective Oct 1, 2026One payment locality44.9K Medicare services in 2024

In Mississippi, Medicare pays $55.51 for 88188 in the office and $55.51 when it’s performed in a hospital or facility.

$55.51Office (non-facility)
$55.51Hospital or facility
−5.0%vs the national office rate ($58.45)

Check a contract rate as a % of Medicare · 88188 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88188 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Mississippi
  2. What 88188 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88188 covers

This service is the professional interpretation and written report of flow cytometry findings from a panel of 9–15 markers. A pathologist or other qualified laboratory professional may evaluate results from peripheral blood, bone marrow, lymph node, or fluid specimens when assessing suspected leukemia, lymphoma, or another hematologic disorder. The report interprets the cell populations and marker pattern in the clinical context; it is not the laboratory work that processes and analyzes the specimen.

Select this code according to the number of markers included in the interpretation: 9–15. The record should support the specimen examined, markers assessed, findings, and resulting interpretation. Report the professional service separately from the applicable technical flow cytometry services; the technical portion is covered by separate codes. This code represents interpretation and reporting only.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Mississippi compares for 88188

Across 109 of 109 payment localities, the office rate for 88188 runs from $55.03 in Arkansas to $78.22 in Alaska. Mississippi pays $55.51. The RVUs are the same everywhere; the geographic indexes change the dollars.

88188 in Mississippi vs other payment areas
  1. Mississippi · this page$55.51
  2. Los Angeles, CA · California$62.56+$7.05
  3. Washington, DC area · District of Columbia$63.88+$8.37
  4. Miami, FL · Florida$62.23+$6.72
  5. Chicago, IL · Illinois$61.41+$5.90
  6. Manhattan, NY · New York$64.94+$9.43
  7. Alaska · Alaska$78.22+$22.71

Other areas in Mississippi first, then benchmark localities. Bars start at $0.

Every other payment area

88188 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$55.41$55.41
ArkansasArkansas$55.03$55.03
ArizonaArizona$57.62$57.62
Bakersfield, CACalifornia$60.08$60.08
Chico, CACalifornia$59.85$59.85
El Centro, CACalifornia$59.86$59.86
Fresno, CACalifornia$59.85$59.85
Hanford, CACalifornia$59.85$59.85

88188 rates by state

Office rate range in each state. Select a state to see its payment localities.

MEWIVTNHMTNDMNMINYMARIWAIDWYSDIAILINOHPANJCTORNVUTCONEMOKYWVVAMDDECAAZNMKSOKARTNNCSCDCTXLAMSALGAFLAKHI

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$55.03

$78.22

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88188 office rate range by state
State / territoryOffice rate rangeLocalities
AK$78.221
AL$55.411
AR$55.031
AZ$57.621
CA$59.85–$69.5029
CO$59.591
CT$60.991
DC$63.881
DE$58.241
FL$58.70–$62.233
GA$56.96–$59.252
GU$59.991
HI$59.991
IA$55.771
ID$56.011
IL$58.07–$61.414
IN$56.151
KS$55.791
KY$56.351
LA$56.37–$57.702
MA$59.59–$63.202
MD$58.89–$63.883
ME$56.30–$57.562
MI$57.20–$59.222
MN$57.541
MO$56.00–$57.623
MS$55.511
MT$58.451
NC$56.561
ND$57.261
NE$55.871
NH$58.911
NJ$61.81–$63.832
NM$57.411
NV$58.131
NY$56.99–$65.955
OH$56.961
OK$56.151
OR$57.79–$60.492
PA$56.92–$60.252
PR$58.611
RI$59.551
SC$56.831
SD$57.121
TN$55.941
TX$56.75–$59.408
UT$57.211
VA$57.57–$63.882
VI$58.611
VT$57.291
WA$59.40–$63.982
WI$56.341
WV$57.041
WY$57.931

See 88188 in every payment locality

How the 88188 rate is calculated

Each of 88188’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88188

RVUs × geographic indexes × conversion factor

Office or facility?

Work1.17

1.17 RVUs× 1.000 GPCI

Practice expense0.52

0.52 RVUs× 1.000 GPCI

Malpractice0.06

0.06 RVUs× 1.000 GPCI

Adjusted RVUs

1.7500

Conversion factor

$33.4009

Medicare rate

$58.45

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Mississippi inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,165

Code
88188
Physician work
1.17
Practice expense
0.52
Malpractice
0.06

GPCI2026.csv

67

Locality
Mississippi
Physician work
1.000
Practice expense
0.861
Malpractice
0.739
Office calculation for 88188 in Mississippi
ComponentRVULocality factorAdjusted
Physician work1.17× 1.0001.1700
Practice expense0.52× 0.8610.4477
Malpractice0.06× 0.7390.0443
Total RVUs1.6621
Conversion factor× 33.4009

Office rate, Mississippi$55.51

Office: (1.17 × 1 + 0.52 × 0.861 + 0.06 × 0.739) × $33.4009 = $55.51

Facility: (1.17 × 1 + 0.52 × 0.861 + 0.06 × 0.739) × $33.4009 = $55.51

Open 88188 in the RVU calculator

Payment rules and modifiers for 88188

The CMS indicators that decide how 88188 is paid alongside other services.

CMS payment indicators · 88188

Flow cytometry, 9–15 markers

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical2Professional component only.

Codes related to 88188

Related codes aren’t interchangeable: bill the code that matches the service performed.

Codes related to 88188
CodeHow it relatesOffice range, Mississippi
Often billed with
88184Flow cytometry, first marker, technical componentTechnical flow cytometry service for the first marker may accompany the professional interpretation.$69.80
88185Flow cytometry add-on, technical work, each additional markerTechnical flow cytometry service for additional markers may accompany the professional interpretation.$19.84
Same family
88187Flow cytometry, 2–8 marker interpretationProfessional interpretation for a smaller panel of 2–8 markers.$33.42
88189Flow cytometry, 16 or more markersProfessional interpretation for a panel of 16 or more markers.$75.58

How 88188 has changed in Mississippi

88188 · Office / nonfacility

$55.51

Effective 2026-10-01

The base rate is $0.29 higher than on 2025-10-01, moving from $55.22 to $55.51 (0.5%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release

  1. January 1, 2026

    RVU26A

    $55.22changed to$55.51

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 1.20 changed to 1.17
    • Practice expense RVU 0.55 changed to 0.52
    • Malpractice RVU 0.05 changed to 0.06
    • Practice expense GPCI 0.852 changed to 0.861
    • Malpractice GPCI 0.768 changed to 0.739

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $57.08changed to$55.22

    • Conversion factor 33.2875 changed to 32.3465
    • Malpractice RVU 0.06 changed to 0.05

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $56.15changed to$57.08

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $58.20changed to$56.15

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.56 changed to 0.55
    • Practice expense GPCI 0.847 changed to 0.852
    • Malpractice GPCI 0.720 changed to 0.768

  5. January 1, 2023

    RVU23A

    $59.12changed to$58.20

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.54 changed to 0.56
    • Malpractice RVU 0.08 changed to 0.06
    • Practice expense GPCI 0.842 changed to 0.847
    • Malpractice GPCI 0.671 changed to 0.720

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $59.20changed to$59.12

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 0.55 changed to 0.54
    • Malpractice RVU 0.05 changed to 0.08

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $62.04changed to$59.20

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 0.57 changed to 0.55
    • Malpractice RVU 0.06 changed to 0.05
    • Practice expense GPCI 0.856 changed to 0.842
    • Malpractice GPCI 0.521 changed to 0.671

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $61.92changed to$62.04

    • Conversion factor 36.0391 changed to 36.0896
    • Practice expense GPCI 0.870 changed to 0.856
    • Malpractice GPCI 0.370 changed to 0.521

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $62.48changed to$61.92

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.59 changed to 0.57

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $70.26changed to$62.48

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 0.84 changed to 0.59
    • Practice expense GPCI 0.867 changed to 0.870
    • Malpractice GPCI 0.492 changed to 0.370

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $87.85changed to$70.26

    • Conversion factor 35.8043 changed to 35.8887
    • Work RVU 1.69 changed to 1.20
    • Practice expense RVU 0.82 changed to 0.84
    • Malpractice RVU 0.09 changed to 0.06
    • Practice expense GPCI 0.864 changed to 0.867
    • Malpractice GPCI 0.613 changed to 0.492

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $87.24changed to$87.85

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 0.79 changed to 0.82

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $86.80changed to$87.24

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    $85.62changed to$86.80

    • Conversion factor 35.8228 changed to 35.7547
    • Practice expense RVU 0.73 changed to 0.79
    • Malpractice RVU 0.10 changed to 0.09
    • Practice expense GPCI 0.865 changed to 0.864
    • Malpractice GPCI 0.687 changed to 0.613

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    $83.36changed to$85.62

    • Conversion factor 34.0230 changed to 35.8228
    • Practice expense RVU 0.79 changed to 0.73
    • Practice expense GPCI 0.866 changed to 0.865
    • Malpractice GPCI 0.761 changed to 0.687

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: $83.36

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$55.51$55.51RVU26D
2026-07-01$55.51$55.51RVU26C
2026-04-01$55.51$55.51RVU26B
2026-01-01$55.51$55.51RVU26A
2025-10-01$55.22$55.22RVU25D
2025-07-01$55.22$55.22RVU25C
2025-04-01$55.22$55.22RVU25B
2025-01-01$55.22$55.22RVU25A
2024-10-01$57.08$57.08RVU24D
2024-07-01$57.08$57.08RVU24C
2024-04-01$57.08$57.08RVU24B
2024-03-09$57.08$57.08RVU24AR
2024-01-01$56.15$56.15RVU24A
2023-10-01$58.20$58.20RVU23D
2023-07-01$58.20$58.20RVU23C
2023-04-01$58.20$58.20RVU23B
2023-01-01$58.20$58.20RVU23A
2022-10-01$59.12$59.12RVU22D
2022-07-01$59.12$59.12RVU22C
2022-04-01$59.12$59.12RVU22B
2022-01-01$59.12$59.12RVU22A
2021-10-01$59.20$59.20RVU21D
2021-07-01$59.20$59.20RVU21C
2021-04-01$59.20$59.20RVU21B
2021-01-01$59.20$59.20RVU21A
2020-10-01$62.04$62.04RVU20D
2020-07-01$62.04$62.04RVU20C
2020-04-01$62.04$62.04RVU20B
2020-01-01$62.04$62.04RVU20A
2019-10-01$61.92$61.92RVU19D
2019-07-01$61.92$61.92RVU19C
2019-04-01$61.92$61.92RVU19B
2019-01-01$61.92$61.92RVU19A
2018-10-01$62.48$62.48RVU18D
2018-07-01$62.48$62.48RVU18C
2018-04-01$62.48$62.48RVU18B
2018-01-01$62.48$62.48RVU18AR1
2017-10-01$70.26$70.26RVU17D
2017-07-01$70.26$70.26RVU17C
2017-04-01$70.26$70.26RVU17B
2017-01-01$70.26$70.26RVU17A
2016-10-01$87.85$87.85RVU16D
2016-07-01$87.85$87.85RVU16C
2016-04-01$87.85$87.85RVU16B
2016-01-01$87.85$87.85RVU16A
2015-10-01$87.24$87.24RVU15D
2015-07-01$87.24$87.24RVU15C
2015-04-01$86.80$86.80RVU15B
2015-01-01$86.80$86.80RVU15A
2014-10-01$85.62$85.62RVU14D
2014-07-01$85.62$85.62RVU14C
2014-04-01$85.62$85.62RVU14B
2014-01-01$85.62$85.62RVU14A
2013-10-01$83.36$83.36RVU13D
2013-07-01$83.36$83.36RVU13C
2013-04-01$83.36$83.36RVU13B
2013-01-01$83.36$83.36RVU13AR

Price 88188 for an earlier date of service

Where the Mississippi rate applies

Mississippi is a Medicare payment area, not a city. Our Census mapping connects it to 427 cities and communities in Mississippi. Some span more than one payment area; confirm with the service ZIP.

  • Abbeville
  • Aberdeen
  • Ackerman
  • Agricola
  • Alcorn State University
  • Algoma
  • Alligator
  • Amory

Browse all communities in Mississippi

88188 billing questions

How is 88188 selected over 88187 or 88189?

Choose 88188 when the interpretation covers 9–15 markers. The neighboring interpretation codes represent 2–8 markers and 16 or more markers, respectively.

Does 88188 include specimen processing and flow analysis?

No. It covers the professional interpretation and report; separate codes represent the technical flow cytometry work.

Should modifier 26 be appended?

No. 88188 is a professional-component-only code for interpretation and reporting.

Is 88188 reported once per marker?

No. Select the interpretation code based on the total marker count; 88188 represents a 9–15-marker analysis, not an individual marker.

What documentation supports reporting 88188?

Document the specimen, the markers assessed, the interpreted findings, and the report. The documentation should support that the interpreted panel falls within the 9–15-marker range.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88188PPRRVU2026_Oct_nonQPP.csv, line 11,165 (RVU26D)
Geographic factors for MississippiGPCI2026.csv, line 67 (RVU26D)

Open CMS sourceHow we calculate rates

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