CPT code 88341: Immunostain, each additional single antibody2026 Medicare rate & RVUs in Mississippi

In Mississippi, Medicare pays $83.61 for 88341 in the office.

Check a contract rate as a % of Medicare · 88341 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 88341 covers

This service covers another single-antibody immunohistochemistry or immunocytochemistry stain on a specimen after its first single-antibody stain. A laboratory applies a distinct antibody, such as a keratin or CD marker, to tissue sections or cytology material. A pathologist interprets the staining to help classify a carcinoma, lymphoma, or other lesion. Hospital pathology departments and independent laboratories perform the staining; the specimen may also have a separately reported surgical pathology examination.

Report one unit for each distinct additional single-antibody stain per specimen, not for each slide or tissue block. Report the initial single-antibody stain on each separately identified specimen with 88342; document the specimen, antibodies tested, and results. Control slides do not generate additional units. As an add-on, 88341 must accompany a primary procedure and is paid within that procedure’s global period. Modifier 26 identifies the pathologist’s interpretation, and modifier TC identifies the laboratory’s staining, reagents, and staff work when components are billed separately. Billing without either modifier identifies the global service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Mississippi compares for 88341

Across 109 of 109 payment localities, the office rate for 88341 runs from $83.39 in Arkansas to $129.42 in San Benito County, CA. Mississippi pays $83.61. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

88341 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 88341 in every payment locality

How the 88341 rate is calculated

Each of 88341’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 88341

The CMS indicators that decide how 88341 is paid alongside other services.

What modifiers do to the payment

When to use modifier 26

Codes related to 88341

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 88341 has changed in Mississippi

Price 88341 for an earlier date of service

Where the Mississippi rate applies

Mississippi is a Medicare payment area, not a city. Our Census mapping connects it to 427 cities and communities in Mississippi. Some span more than one payment area; confirm with the service ZIP.

• Abbeville
• Aberdeen
• Ackerman
• Agricola
• Alcorn State University
• Algoma
• Alligator
• Amory

Browse all communities in Mississippi

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates