CPT code 88342: Antibody stain, first single antibody per specimen2026 Medicare rate & RVUs in Rhode Island
Report 88342 for the first single-antibody immunohistochemical or immunocytochemical stain on each specimen when a pathologist interprets stained tissue or cells.
In Rhode Island, Medicare pays $113.45 for 88342 in the office.
Check a contract rate as a % of Medicare · 88342 nationwide
Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.
On this page 11 sections
What 88342 covers
Code 88342 covers the first single-antibody immunohistochemical or immunocytochemical stain on a tissue or cytology specimen, such as a cell block. A histology laboratory prepares the stained material, and a pathologist interprets the result to characterize a tumor, identify metastatic carcinoma in a lymph node, or investigate an infectious organism. These services may be performed in hospital, independent, or office-based laboratories.
Report one unit per separately identifiable specimen receiving a single-antibody stain, not per slide or tissue block. Use 88341 for additional single-antibody stains on that specimen and 88344 for a multiplex antibody stain procedure. Controls are included rather than counted as additional units. Documentation should identify the specimen, antibodies, and findings. CMS recognizes a technical component (modifier TC) for stain preparation, reagents, staff, and equipment, and a professional component (modifier 26) for interpretation. An entity performing both reports the global service without a modifier. A pathologist interpreting staining performed by a hospital laboratory generally reports 88342 with modifier 26.
This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.
How Rhode Island compares for 88342
Across 109 of 109 payment localities, the office rate for 88342 runs from $97.65 in Arkansas to $150.80 in San Benito County, CA. Rhode Island pays $113.45. The RVUs are the same everywhere; the geographic indexes change the dollars.
- Rhode Island · this page$113.45
- Los Angeles, CA · California$126.82+$13.37
- Washington, DC area · District of Columbia$126.98+$13.53
- Miami, FL · Florida$114.80+$1.35
- Chicago, IL · Illinois$111.68−$1.77
- Manhattan, NY · New York$126.14+$12.69
- Alaska · Alaska$126.92+$13.47
Other areas in Rhode Island first, then benchmark localities. Bars start at $0.
Every other payment area
| Payment locality | Office | Facility |
|---|---|---|
| AlabamaAlabama | $99.08 | — |
| ArkansasArkansas | $97.65 | — |
| ArizonaArizona | $107.43 | — |
| Bakersfield, CACalifornia | $118.73 | — |
| Chico, CACalifornia | $118.64 | — |
| El Centro, CACalifornia | $118.64 | — |
| Fresno, CACalifornia | $118.64 | — |
| Hanford, CACalifornia | $118.64 | — |
| Madera, CACalifornia | $118.64 | — |
| Merced, CACalifornia | $118.64 | — |
| Modesto, CACalifornia | $118.64 | — |
| Napa, CACalifornia | $138.94 | — |
| Oxnard, CACalifornia | $126.41 | — |
| Redding, CACalifornia | $118.64 | — |
| Rest of CaliforniaCalifornia | $118.64 | — |
| Riverside, CACalifornia | $118.87 | — |
| Sacramento, CACalifornia | $124.89 | — |
| Salinas, CACalifornia | $124.43 | — |
| San Diego, CACalifornia | $127.62 | — |
| Marin County, CACalifornia | $147.62 | — |
| San Francisco, CACalifornia | $147.60 | — |
| San Benito County, CACalifornia | $150.80 | — |
| Santa Clara County, CACalifornia | $150.70 | — |
| San Luis Obispo, CACalifornia | $122.37 | — |
| Santa Cruz, CACalifornia | $129.06 | — |
| Santa Maria, CACalifornia | $124.96 | — |
| Santa Rosa, CACalifornia | $130.39 | — |
| Stockton, CACalifornia | $118.64 | — |
| Vallejo, CACalifornia | $138.91 | — |
| Visalia, CACalifornia | $118.64 | — |
| Yuba City, CACalifornia | $118.64 | — |
| ColoradoColorado | $115.91 | — |
| ConnecticutConnecticut | $117.50 | — |
| DelawareDelaware | $109.23 | — |
| Fort Lauderdale, FLFlorida | $111.89 | — |
| Rest of FloridaFlorida | $106.74 | — |
| Atlanta, GAGeorgia | $111.81 | — |
| Rest of GeorgiaGeorgia | $100.97 | — |
| Hawaii, Guam, HIHawaii | $121.84 | — |
| IowaIowa | $102.44 | — |
| IdahoIdaho | $102.92 | — |
| East St. Louis, ILIllinois | $103.95 | — |
| Rest of IllinoisIllinois | $103.04 | — |
| Suburban Chicago, ILIllinois | $113.24 | — |
| IndianaIndiana | $103.54 | — |
| KansasKansas | $101.55 | — |
| KentuckyKentucky | $100.53 | — |
| New Orleans, LALouisiana | $105.19 | — |
| Rest of LouisianaLouisiana | $100.21 | — |
| Metropolitan Boston, MAMassachusetts | $127.93 | — |
| Rest of MassachusettsMassachusetts | $115.05 | — |
| Baltimore area, MDMaryland | $117.08 | — |
| Rest of MarylandMaryland | $111.44 | — |
| Rest of MaineMaine | $103.02 | — |
| Southern Maine, MEMaine | $109.19 | — |
| Detroit, MIMichigan | $107.64 | — |
| Rest of MichiganMichigan | $102.75 | — |
| MinnesotaMinnesota | $112.27 | — |
| Metropolitan Kansas City, MOMissouri | $104.91 | — |
| Metropolitan St. Louis, MOMissouri | $106.06 | — |
| Rest of MissouriMissouri | $98.22 | — |
| MississippiMississippi | $97.98 | — |
| MontanaMontana | $110.22 | — |
| North CarolinaNorth Carolina | $104.16 | — |
| North DakotaNorth Dakota | $109.83 | — |
| NebraskaNebraska | $103.12 | — |
| New HampshireNew Hampshire | $113.70 | — |
| Northern New JerseyNew Jersey | $125.59 | — |
| Rest of New JerseyNew Jersey | $119.19 | — |
| New MexicoNew Mexico | $103.15 | — |
| NevadaNevada | $110.20 | — |
| NYC suburbs and Long Island, NYNew York | $128.66 | — |
| Poughkeepsie and northern NYC suburbs, NYNew York | $119.64 | — |
| Queens, NYNew York | $127.78 | — |
| Rest of New YorkNew York | $105.68 | — |
| OhioOhio | $102.67 | — |
| OklahomaOklahoma | $100.78 | — |
| Portland, OROregon | $120.05 | — |
| Rest of OregonOregon | $109.68 | — |
| Metropolitan Philadelphia, PAPennsylvania | $114.32 | — |
| Rest of PennsylvaniaPennsylvania | $103.07 | — |
| Puerto RicoPuerto Rico | $111.17 | — |
| South CarolinaSouth Carolina | $103.52 | — |
| South DakotaSouth Dakota | $109.78 | — |
| TennesseeTennessee | $102.01 | — |
| Austin, TXTexas | $115.23 | — |
| Beaumont, TXTexas | $102.36 | — |
| Brazoria, TXTexas | $109.48 | — |
| Dallas, TXTexas | $109.99 | — |
| Fort Worth, TXTexas | $109.13 | — |
| Galveston, TXTexas | $109.68 | — |
| Houston, TXTexas | $110.05 | — |
| Rest of TexasTexas | $105.73 | — |
| UtahUtah | $104.94 | — |
| VirginiaVirginia | $108.55 | — |
| Virgin Islands, VIUnited States Virgin Islands | $111.17 | — |
| VermontVermont | $109.02 | — |
| Rest of WashingtonWashington | $114.96 | — |
| King County, WAWashington | $130.95 | — |
| WisconsinWisconsin | $106.11 | — |
| West VirginiaWest Virginia | $99.13 | — |
| WyomingWyoming | $110.05 | — |
88342 rates by state
Office rate range in each state. Select a state to see its payment localities.
Explore a state
Local rates. Clear comparisons.
Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.
$97.65
$134.72
Color shows the midpoint of each state’s locality range.
View every state and territory as a table
| State / territory | Office rate range | Localities |
|---|---|---|
| AK | $126.92 | 1 |
| AL | $99.08 | 1 |
| AR | $97.65 | 1 |
| AZ | $107.43 | 1 |
| CA | $118.64–$150.80 | 29 |
| CO | $115.91 | 1 |
| CT | $117.50 | 1 |
| DC | $126.98 | 1 |
| DE | $109.23 | 1 |
| FL | $106.74–$114.80 | 3 |
| GA | $100.97–$111.81 | 2 |
| GU | $121.84 | 1 |
| HI | $121.84 | 1 |
| IA | $102.44 | 1 |
| ID | $102.92 | 1 |
| IL | $103.04–$113.24 | 4 |
| IN | $103.54 | 1 |
| KS | $101.55 | 1 |
| KY | $100.53 | 1 |
| LA | $100.21–$105.19 | 2 |
| MA | $115.05–$127.93 | 2 |
| MD | $111.44–$126.98 | 3 |
| ME | $103.02–$109.19 | 2 |
| MI | $102.75–$107.64 | 2 |
| MN | $112.27 | 1 |
| MO | $98.22–$106.06 | 3 |
| MS | $97.98 | 1 |
| MT | $110.22 | 1 |
| NC | $104.16 | 1 |
| ND | $109.83 | 1 |
| NE | $103.12 | 1 |
| NH | $113.70 | 1 |
| NJ | $119.19–$125.59 | 2 |
| NM | $103.15 | 1 |
| NV | $110.20 | 1 |
| NY | $105.68–$128.66 | 5 |
| OH | $102.67 | 1 |
| OK | $100.78 | 1 |
| OR | $109.68–$120.05 | 2 |
| PA | $103.07–$114.32 | 2 |
| PR | $111.17 | 1 |
| RI | $113.45 | 1 |
| SC | $103.52 | 1 |
| SD | $109.78 | 1 |
| TN | $102.01 | 1 |
| TX | $102.36–$115.23 | 8 |
| UT | $104.94 | 1 |
| VA | $108.55–$126.98 | 2 |
| VI | $111.17 | 1 |
| VT | $109.02 | 1 |
| WA | $114.96–$130.95 | 2 |
| WI | $106.11 | 1 |
| WV | $99.13 | 1 |
| WY | $110.05 | 1 |
How the 88342 rate is calculated
Each of 88342’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.
How the rate is built · 88342
RVUs × geographic indexes × conversion factor
Work0.68
0.68 RVUs× 1.000 GPCI
Practice expense2.60
2.60 RVUs× 1.000 GPCI
Malpractice0.02
0.02 RVUs× 1.000 GPCI
Adjusted RVUs
3.3000
Conversion factor
$33.4009
Medicare rate
$110.22
Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.
The exact Rhode Island inputs and CMS source lines
PPRRVU2026_Oct_nonQPP.csv
11,251
- Code
- 88342
- Physician work
- 0.68
- Practice expense
- 2.60
- Malpractice
- 0.02
GPCI2026.csv
92
- Locality
- Rhode Island
- Physician work
- 1.019
- Practice expense
- 1.033
- Malpractice
- 0.892
| Component | RVU | Locality factor | Adjusted |
|---|---|---|---|
| Physician work | 0.68 | × 1.019 | 0.6929 |
| Practice expense | 2.60 | × 1.033 | 2.6858 |
| Malpractice | 0.02 | × 0.892 | 0.0178 |
| Total RVUs | 3.3966 | ||
| Conversion factor | × 33.4009 | ||
Office rate, Rhode Island$113.45
Office: (0.68 × 1.019 + 2.6 × 1.033 + 0.02 × 0.892) × $33.4009 = $113.45
Payment rules and modifiers for 88342
The CMS indicators that decide how 88342 is paid alongside other services.
CMS payment indicators · 88342
Antibody stain, first single antibody per specimen
| Rule | CMS value | What it means |
|---|---|---|
| Global period | XXX | The global surgery concept doesn’t apply. |
| Multiple procedures | 0 | No multiple-procedure reduction. |
| Bilateral (modifier 50) | 0 | The 150% bilateral adjustment doesn’t apply. |
| Assistant at surgery (80/81/82/AS) | 0 | Not paid without supporting documentation. |
| Co-surgeons (62) | 0 | Not permitted. |
| Team surgery (66) | 0 | Not permitted. |
| Professional/technical | 1 | Diagnostic test with separate professional (26) and technical (TC) components. |
What modifiers do to the payment
Modifier 26 · payment effect
With and without the modifier
88342 without 26 · national office
$110.22
Antibody stain, first single antibody per specimen
88342-26 · Professional component
$32.73
Pays only the interpretation and report.
How 88342 has changed in Rhode Island
88342 · Office / nonfacility
$113.45
Effective 2026-10-01
The base rate is $0.63 higher than on 2025-10-01, moving from $112.82 to $113.45 (0.6%).
It is unchanged from the immediately preceding available release, effective 2026-07-01.
One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.
What changed, release by release
January 1, 2026
RVU26A
$112.82changed to$113.45
- Conversion factor 32.3465 changed to 33.4009
- Work RVU 0.70 changed to 0.68
- Practice expense RVU 2.65 changed to 2.60
- Work GPCI 1.025 changed to 1.019
- Practice expense GPCI 1.039 changed to 1.033
- Malpractice GPCI 0.849 changed to 0.892
Held through RVU26B, RVU26C, RVU26D.
January 1, 2025
RVU25A
$109.53changed to$112.82
- Conversion factor 33.2875 changed to 32.3465
- Practice expense RVU 2.46 changed to 2.65
Held through RVU25B, RVU25C, RVU25D.
March 9, 2024
RVU24AR
$107.74changed to$109.53
- Conversion factor 32.7442 changed to 33.2875
Held through RVU24B, RVU24C, RVU24D.
January 1, 2024
RVU24A
$104.84changed to$107.74
- Conversion factor 33.8872 changed to 32.7442
- Practice expense RVU 2.26 changed to 2.46
- Work GPCI 1.023 changed to 1.025
- Practice expense GPCI 1.044 changed to 1.039
- Malpractice GPCI 0.915 changed to 0.849
January 1, 2023
RVU23A
$106.65changed to$104.84
- Conversion factor 34.6062 changed to 33.8872
- Practice expense RVU 2.24 changed to 2.26
- Work GPCI 1.021 changed to 1.023
- Practice expense GPCI 1.048 changed to 1.044
- Malpractice GPCI 0.981 changed to 0.915
Held through RVU23B, RVU23C, RVU23D.
January 1, 2022
RVU22A
$110.46changed to$106.65
- Conversion factor 34.8931 changed to 34.6062
- Practice expense RVU 2.32 changed to 2.24
Held through RVU22B, RVU22C, RVU22D.
January 1, 2021
RVU21A
$111.76changed to$110.46
- Conversion factor 36.0896 changed to 34.8931
- Practice expense RVU 2.25 changed to 2.32
- Work GPCI 1.024 changed to 1.021
- Practice expense GPCI 1.049 changed to 1.048
- Malpractice GPCI 0.990 changed to 0.981
Held through RVU21B, RVU21C, RVU21D.
January 1, 2020
RVU20A
$113.27changed to$111.76
- Conversion factor 36.0391 changed to 36.0896
- Practice expense RVU 2.28 changed to 2.25
- Malpractice RVU 0.03 changed to 0.02
- Work GPCI 1.027 changed to 1.024
- Practice expense GPCI 1.050 changed to 1.049
- Malpractice GPCI 0.999 changed to 0.990
Held through RVU20B, RVU20C, RVU20D.
January 1, 2019
RVU19A
$116.54changed to$113.27
- Conversion factor 35.9996 changed to 36.0391
- Practice expense RVU 2.37 changed to 2.28
Held through RVU19B, RVU19C, RVU19D.
January 1, 2018
RVU18AR1
$113.16changed to$116.54
- Conversion factor 35.8887 changed to 35.9996
- Practice expense RVU 2.29 changed to 2.37
- Work GPCI 1.025 changed to 1.027
- Practice expense GPCI 1.052 changed to 1.050
- Malpractice GPCI 0.879 changed to 0.999
Held through RVU18B, RVU18C, RVU18D.
January 1, 2017
RVU17A
$112.01changed to$113.16
- Conversion factor 35.8043 changed to 35.8887
- Practice expense RVU 2.27 changed to 2.29
- Work GPCI 1.022 changed to 1.025
- Practice expense GPCI 1.053 changed to 1.052
- Malpractice GPCI 0.759 changed to 0.879
Held through RVU17B, RVU17C, RVU17D.
January 1, 2016
RVU16A
$94.74changed to$112.01
- Conversion factor 35.9335 changed to 35.8043
- Practice expense RVU 1.81 changed to 2.27
- Malpractice RVU 0.02 changed to 0.03
Held through RVU16B, RVU16C, RVU16D.
July 1, 2015
RVU15C
$94.27changed to$94.74
- Conversion factor 35.7547 changed to 35.9335
Held through RVU15D.
January 1, 2015
RVU15A
No ratechanged to$94.27
Held through RVU15B.
January 1, 2014
RVU14A
No ratechanged toNo rate
Held through RVU14B, RVU14C, RVU14D.
January 1, 2013
RVU13AR
Earliest loaded release: No rate
Held through RVU13B, RVU13C, RVU13D.
| Effective from | Office | Facility | CMS release |
|---|---|---|---|
| 2026-10-01 | $113.45 | Not available in this setting | RVU26D |
| 2026-07-01 | $113.45 | Not available in this setting | RVU26C |
| 2026-04-01 | $113.45 | Not available in this setting | RVU26B |
| 2026-01-01 | $113.45 | Not available in this setting | RVU26A |
| 2025-10-01 | $112.82 | Not available in this setting | RVU25D |
| 2025-07-01 | $112.82 | Not available in this setting | RVU25C |
| 2025-04-01 | $112.82 | Not available in this setting | RVU25B |
| 2025-01-01 | $112.82 | Not available in this setting | RVU25A |
| 2024-10-01 | $109.53 | Not available in this setting | RVU24D |
| 2024-07-01 | $109.53 | Not available in this setting | RVU24C |
| 2024-04-01 | $109.53 | Not available in this setting | RVU24B |
| 2024-03-09 | $109.53 | Not available in this setting | RVU24AR |
| 2024-01-01 | $107.74 | Not available in this setting | RVU24A |
| 2023-10-01 | $104.84 | Not available in this setting | RVU23D |
| 2023-07-01 | $104.84 | Not available in this setting | RVU23C |
| 2023-04-01 | $104.84 | Not available in this setting | RVU23B |
| 2023-01-01 | $104.84 | Not available in this setting | RVU23A |
| 2022-10-01 | $106.65 | Not available in this setting | RVU22D |
| 2022-07-01 | $106.65 | Not available in this setting | RVU22C |
| 2022-04-01 | $106.65 | Not available in this setting | RVU22B |
| 2022-01-01 | $106.65 | Not available in this setting | RVU22A |
| 2021-10-01 | $110.46 | Not available in this setting | RVU21D |
| 2021-07-01 | $110.46 | Not available in this setting | RVU21C |
| 2021-04-01 | $110.46 | Not available in this setting | RVU21B |
| 2021-01-01 | $110.46 | Not available in this setting | RVU21A |
| 2020-10-01 | $111.76 | Not available in this setting | RVU20D |
| 2020-07-01 | $111.76 | Not available in this setting | RVU20C |
| 2020-04-01 | $111.76 | Not available in this setting | RVU20B |
| 2020-01-01 | $111.76 | Not available in this setting | RVU20A |
| 2019-10-01 | $113.27 | Not available in this setting | RVU19D |
| 2019-07-01 | $113.27 | Not available in this setting | RVU19C |
| 2019-04-01 | $113.27 | Not available in this setting | RVU19B |
| 2019-01-01 | $113.27 | Not available in this setting | RVU19A |
| 2018-10-01 | $116.54 | Not available in this setting | RVU18D |
| 2018-07-01 | $116.54 | Not available in this setting | RVU18C |
| 2018-04-01 | $116.54 | Not available in this setting | RVU18B |
| 2018-01-01 | $116.54 | Not available in this setting | RVU18AR1 |
| 2017-10-01 | $113.16 | Not available in this setting | RVU17D |
| 2017-07-01 | $113.16 | Not available in this setting | RVU17C |
| 2017-04-01 | $113.16 | Not available in this setting | RVU17B |
| 2017-01-01 | $113.16 | Not available in this setting | RVU17A |
| 2016-10-01 | $112.01 | Not available in this setting | RVU16D |
| 2016-07-01 | $112.01 | Not available in this setting | RVU16C |
| 2016-04-01 | $112.01 | Not available in this setting | RVU16B |
| 2016-01-01 | $112.01 | Not available in this setting | RVU16A |
| 2015-10-01 | $94.74 | Not available in this setting | RVU15D |
| 2015-07-01 | $94.74 | Not available in this setting | RVU15C |
| 2015-04-01 | $94.27 | Not available in this setting | RVU15B |
| 2015-01-01 | $94.27 | Not available in this setting | RVU15A |
| 2014-10-01 | Separate payment rules apply | Separate payment rules apply | RVU14D |
| 2014-07-01 | Separate payment rules apply | Separate payment rules apply | RVU14C |
| 2014-04-01 | Separate payment rules apply | Separate payment rules apply | RVU14B |
| 2014-01-01 | Separate payment rules apply | Separate payment rules apply | RVU14A |
| 2013-10-01 | Rate data unavailable | Not available in this setting | RVU13D |
| 2013-07-01 | Rate data unavailable | Not available in this setting | RVU13C |
| 2013-04-01 | Rate data unavailable | Not available in this setting | RVU13B |
| 2013-01-01 | Rate data unavailable | Not available in this setting | RVU13AR |
Where the Rhode Island rate applies
Rhode Island is a Medicare payment area, not a city. Our Census mapping connects it to 36 cities and communities in Rhode Island. Some span more than one payment area; confirm with the service ZIP.
- Ashaway
- Bradford
- Carolina
- Central Falls
- Charlestown
- Chepachet
- Clayville
- Cranston
88342 billing questions
How many units of this code can be reported when several antibodies are run on one specimen?
Report one unit of 88342 for the first single-antibody stain on that specimen. Report each additional single-antibody stain on the same specimen with add-on code 88341.
If two separate specimens each receive single-antibody stains, can this code be reported twice?
Yes. Report 88342 once for each separately identifiable specimen receiving a single-antibody stain, with 88341 for additional single-antibody stains on each specimen.
Are control slides billed separately?
No. Positive and negative controls run with the stain are included and are not counted as additional units.
When should 88360 or 88361 be used instead?
Use 88360 for manual or 88361 for computer-assisted quantitative or semiquantitative tumor immunostaining, such as ER, PR, or HER2 scoring. Do not also report 88342 for the same antibody on the same specimen.
Which modifier does a pathologist use when the hospital lab performs the staining?
The pathologist reports modifier 26 for the interpretation; the hospital performs the technical work. An entity performing both components reports the global code without a modifier.
Does a stain with two antibodies on one slide count here?
Use 88344 when the service is a multiplex antibody stain procedure. Combining antibodies in a cocktail does not, by itself, establish that a multiplex procedure was performed.
Where these rates come from
FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.
CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027
Show the CMS file lines behind this rate
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