CPT code 88342: Antibody stain, first single antibody per specimen2026 Medicare rate & RVUs in South Dakota

In South Dakota, Medicare pays $109.78 for 88342 in the office.

Check a contract rate as a % of Medicare · 88342 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

What 88342 covers

Code 88342 covers the first single-antibody immunohistochemical or immunocytochemical stain on a tissue or cytology specimen, such as a cell block. A histology laboratory prepares the stained material, and a pathologist interprets the result to characterize a tumor, identify metastatic carcinoma in a lymph node, or investigate an infectious organism. These services may be performed in hospital, independent, or office-based laboratories.

Report one unit per separately identifiable specimen receiving a single-antibody stain, not per slide or tissue block. Use 88341 for additional single-antibody stains on that specimen and 88344 for a multiplex antibody stain procedure. Controls are included rather than counted as additional units. Documentation should identify the specimen, antibodies, and findings. CMS recognizes a technical component (modifier TC) for stain preparation, reagents, staff, and equipment, and a professional component (modifier 26) for interpretation. An entity performing both reports the global service without a modifier. A pathologist interpreting staining performed by a hospital laboratory generally reports 88342 with modifier 26.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How South Dakota compares for 88342

Across 109 of 109 payment localities, the office rate for 88342 runs from $97.65 in Arkansas to $150.80 in San Benito County, CA. South Dakota pays $109.78. The RVUs are the same everywhere; the geographic indexes change the dollars.

Every other payment area

88342 rates by state

Office rate range in each state. Select a state to see its payment localities.

See 88342 in every payment locality

How the 88342 rate is calculated

Each of 88342’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

Payment rules and modifiers for 88342

The CMS indicators that decide how 88342 is paid alongside other services.

What modifiers do to the payment

When to use modifier 26

Codes related to 88342

Related codes aren’t interchangeable: bill the code that matches the service performed.

How 88342 has changed in South Dakota

Price 88342 for an earlier date of service

Where the South Dakota rate applies

South Dakota is a Medicare payment area, not a city. Our Census mapping connects it to 485 cities and communities in South Dakota. Some span more than one payment area; confirm with the service ZIP.

• Aberdeen
• Agar
• Agency Village
• Akaska
• Albee
• Alcester
• Alexandria
• Allen

Browse all communities in South Dakota

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Open CMS sourceHow we calculate rates