CPT code 88375: Optical endomicroscopy, professional component2026 Medicare rate & RVUs in Delaware

Report this service for a physician’s interpretation and report of real-time or recorded optical endomicroscopy images obtained during microscopic tissue assessment.

CMS RVU26DEffective Oct 1, 2026One payment locality269 Medicare services in 2024

In Delaware, Medicare pays $44.91 for 88375 in the office and $44.91 when it’s performed in a hospital or facility.

$44.91Office (non-facility)
$44.91Hospital or facility
−0.4%vs the national office rate ($45.09)

Check a contract rate as a % of Medicare · 88375 nationwide

Medicare allowed amount for participating (non-QP) physicians, before deductible, coinsurance and claim adjustments. Not a patient’s bill or a hospital charge.

We’ll open 88375 for the payment locality that covers the ZIP.

On this page 11 sections
  1. Rate in Delaware
  2. What 88375 covers
  3. Compared with other areas
  4. Rate map
  5. How it’s calculated
  6. Payment rules
  7. Related codes
  8. Rate history
  9. Where it applies
  10. Billing questions
  11. Sources

What 88375 covers

Optical endomicroscopy produces microscopic images of tissue in a clinical setting, commonly during gastrointestinal endoscopy. The physician reviews real-time or recorded images to assess cellular and tissue features and prepares an interpretation and report. This is image-based assessment, distinct from examining a removed specimen on a conventional pathology slide.

Report 88375 for the professional interpretation and report, not for acquiring the images or furnishing the equipment and other technical work. CMS identifies this as a professional-component-only code; a separate code covers the technical portion. Documentation should identify the optical endomicroscopy study, the images reviewed, the physician’s findings, and the resulting interpretation. When optical endomicroscopy is performed as part of an endoscopic procedure, the endoscopy code describes that procedure; 88375 represents the separately coded interpretation service.

This summary was written with AI assistance from CMS physician fee schedule data and checked against the CMS billing rules shown here. Rates on this page come directly from CMS files.

How Delaware compares for 88375

Across 109 of 109 payment localities, the office rate for 88375 runs from $42.35 in Arkansas to $60.09 in Alaska. Delaware pays $44.91. The RVUs are the same everywhere; the geographic indexes change the dollars.

88375 in Delaware vs other payment areas
  1. Delaware · this page$44.91
  2. Los Angeles, CA · California$48.25+$3.34
  3. Washington, DC area · District of Columbia$49.32+$4.41
  4. Miami, FL · Florida$48.21+$3.30
  5. Chicago, IL · Illinois$47.53+$2.62
  6. Manhattan, NY · New York$50.19+$5.28
  7. Alaska · Alaska$60.09+$15.18

Other areas in Delaware first, then benchmark localities. Bars start at $0.

Every other payment area

88375 in every other Medicare payment locality
Payment localityOfficeFacility
AlabamaAlabama$42.65$42.65
ArkansasArkansas$42.35$42.35
ArizonaArizona$44.43$44.43
Bakersfield, CACalifornia$46.32$46.32
Chico, CACalifornia$46.14$46.14
El Centro, CACalifornia$46.14$46.14
Fresno, CACalifornia$46.14$46.14
Hanford, CACalifornia$46.14$46.14

88375 rates by state

Office rate range in each state. Select a state to see its payment localities.

Explore a state

Local rates. Clear comparisons.

Hover or focus a tile to see its rate range. Select it to open the state’s fee schedule.

$42.35

$60.09

Color shows the midpoint of each state’s locality range.

View every state and territory as a table
88375 office rate range by state
State / territoryOffice rate rangeLocalities
AK$60.091
AL$42.651
AR$42.351
AZ$44.431
CA$46.14–$53.6429
CO$45.961
CT$47.091
DC$49.321
DE$44.911
FL$45.33–$48.213
GA$43.93–$45.742
GU$46.261
HI$46.261
IA$42.921
ID$43.121
IL$44.84–$47.534
IN$43.231
KS$42.951
KY$43.431
LA$43.45–$44.512
MA$45.95–$48.782
MD$45.42–$49.323
ME$43.36–$44.352
MI$44.12–$45.762
MN$44.311
MO$43.16–$44.443
MS$42.751
MT$45.091
NC$43.571
ND$44.101
NE$43.001
NH$45.441
NJ$47.70–$49.272
NM$44.291
NV$44.831
NY$43.91–$51.015
OH$43.911
OK$43.251
OR$44.54–$46.662
PA$43.88–$46.512
PR$45.221
RI$45.931
SC$43.801
SD$43.981
TN$43.071
TX$43.74–$45.868
UT$44.101
VA$44.37–$49.322
VI$45.221
VT$44.131
WA$45.80–$49.382
WI$43.361
WV$44.021
WY$44.661

See 88375 in every payment locality

How the 88375 rate is calculated

Each of 88375’s three RVUs is multiplied by a geographic index (GPCI) for the payment locality, added up, and multiplied by the conversion factor. Drag the indexes or enter a ZIP to see what moves the rate.

How the rate is built · 88375

RVUs × geographic indexes × conversion factor

Office or facility?

Work0.89

0.89 RVUs× 1.000 GPCI

Practice expense0.41

0.41 RVUs× 1.000 GPCI

Malpractice0.05

0.05 RVUs× 1.000 GPCI

Adjusted RVUs

1.3500

Conversion factor

$33.4009

Medicare rate

$45.09

Every GPCI starts at 1.000, the national rate. Enter a ZIP or drag a slider.

The exact Delaware inputs and CMS source lines

PPRRVU2026_Oct_nonQPP.csv

11,313

Code
88375
Physician work
0.89
Practice expense
0.41
Malpractice
0.05

GPCI2026.csv

40

Locality
Delaware
Physician work
1.005
Practice expense
0.988
Malpractice
0.899
Office calculation for 88375 in Delaware
ComponentRVULocality factorAdjusted
Physician work0.89× 1.0050.8944
Practice expense0.41× 0.9880.4051
Malpractice0.05× 0.8990.0450
Total RVUs1.3445
Conversion factor× 33.4009

Office rate, Delaware$44.91

Office: (0.89 × 1.005 + 0.41 × 0.988 + 0.05 × 0.899) × $33.4009 = $44.91

Facility: (0.89 × 1.005 + 0.41 × 0.988 + 0.05 × 0.899) × $33.4009 = $44.91

Open 88375 in the RVU calculator

Payment rules and modifiers for 88375

The CMS indicators that decide how 88375 is paid alongside other services.

CMS payment indicators · 88375

Optical endomicroscopy, professional component

RuleCMS valueWhat it means
Global periodXXXThe global surgery concept doesn’t apply.
Multiple procedures0No multiple-procedure reduction.
Bilateral (modifier 50)0The 150% bilateral adjustment doesn’t apply.
Assistant at surgery (80/81/82/AS)0Not paid without supporting documentation.
Co-surgeons (62)0Not permitted.
Team surgery (66)0Not permitted.
Professional/technical2Professional component only.

How 88375 has changed in Delaware

88375 · Office / nonfacility

$44.91

Effective 2026-10-01

The base rate is $0.14 lower than on 2025-10-01, moving from $45.05 to $44.91 (0.3%).

It is unchanged from the immediately preceding available release, effective 2026-07-01.

Base rate by release · bars start at $0 · select a bar to compare

One bar per available release, ordered by effective date. Missing rates remain gaps. These comparisons hold the code, setting and locality identifiers constant; they do not isolate which policy or input caused a change.

What changed, release by release
  1. January 1, 2026

    RVU26A

    $45.05changed to$44.91

    • Conversion factor 32.3465 changed to 33.4009
    • Work RVU 0.91 changed to 0.89
    • Practice expense RVU 0.44 changed to 0.41
    • Malpractice RVU 0.04 changed to 0.05
    • Work GPCI 1.009 changed to 1.005
    • Practice expense GPCI 0.992 changed to 0.988
    • Malpractice GPCI 0.949 changed to 0.899

    Held through RVU26B, RVU26C, RVU26D.

  2. January 1, 2025

    RVU25A

    $46.67changed to$45.05

    • Conversion factor 33.2875 changed to 32.3465
    • Malpractice RVU 0.05 changed to 0.04

    Held through RVU25B, RVU25C, RVU25D.

  3. March 9, 2024

    RVU24AR

    $45.91changed to$46.67

    • Conversion factor 32.7442 changed to 33.2875

    Held through RVU24B, RVU24C, RVU24D.

  4. January 1, 2024

    RVU24A

    $47.68changed to$45.91

    • Conversion factor 33.8872 changed to 32.7442
    • Practice expense RVU 0.45 changed to 0.44
    • Malpractice RVU 0.04 changed to 0.05
    • Work GPCI 1.007 changed to 1.009
    • Practice expense GPCI 1.007 changed to 0.992
    • Malpractice GPCI 0.938 changed to 0.949
  5. January 1, 2023

    RVU23A

    $48.81changed to$47.68

    • Conversion factor 34.6062 changed to 33.8872
    • Practice expense RVU 0.44 changed to 0.45
    • Malpractice RVU 0.05 changed to 0.04
    • Work GPCI 1.005 changed to 1.007
    • Practice expense GPCI 1.022 changed to 1.007
    • Malpractice GPCI 0.927 changed to 0.938

    Held through RVU23B, RVU23C, RVU23D.

  6. January 1, 2022

    RVU22A

    $49.58changed to$48.81

    • Conversion factor 34.8931 changed to 34.6062
    • Practice expense RVU 0.45 changed to 0.44

    Held through RVU22B, RVU22C, RVU22D.

  7. January 1, 2021

    RVU21A

    $51.83changed to$49.58

    • Conversion factor 36.0896 changed to 34.8931
    • Practice expense RVU 0.46 changed to 0.45
    • Work GPCI 1.006 changed to 1.005
    • Practice expense GPCI 1.021 changed to 1.022
    • Malpractice GPCI 1.023 changed to 0.927

    Held through RVU21B, RVU21C, RVU21D.

  8. January 1, 2020

    RVU20A

    $51.93changed to$51.83

    • Conversion factor 36.0391 changed to 36.0896
    • Work GPCI 1.007 changed to 1.006
    • Practice expense GPCI 1.019 changed to 1.021
    • Malpractice GPCI 1.119 changed to 1.023

    Held through RVU20B, RVU20C, RVU20D.

  9. January 1, 2019

    RVU19A

    $52.98changed to$51.93

    • Conversion factor 35.9996 changed to 36.0391
    • Practice expense RVU 0.49 changed to 0.46

    Held through RVU19B, RVU19C, RVU19D.

  10. January 1, 2018

    RVU18AR1

    $47.84changed to$52.98

    • Conversion factor 35.8887 changed to 35.9996
    • Practice expense RVU 0.35 changed to 0.49
    • Work GPCI 1.010 changed to 1.007
    • Practice expense GPCI 1.025 changed to 1.019
    • Malpractice GPCI 1.101 changed to 1.119

    Held through RVU18B, RVU18C, RVU18D.

  11. January 1, 2017

    RVU17A

    $51.15changed to$47.84

    • Conversion factor 35.8043 changed to 35.8887
    • Practice expense RVU 0.44 changed to 0.35
    • Work GPCI 1.012 changed to 1.010
    • Practice expense GPCI 1.031 changed to 1.025
    • Malpractice GPCI 1.083 changed to 1.101

    Held through RVU17B, RVU17C, RVU17D.

  12. January 1, 2016

    RVU16A

    $49.12changed to$51.15

    • Conversion factor 35.9335 changed to 35.8043
    • Practice expense RVU 0.38 changed to 0.44

    Held through RVU16B, RVU16C, RVU16D.

  13. July 1, 2015

    RVU15C

    $48.87changed to$49.12

    • Conversion factor 35.7547 changed to 35.9335

    Held through RVU15D.

  14. January 1, 2015

    RVU15A

    No ratechanged to$48.87

    Held through RVU15B.

  15. January 1, 2014

    RVU14A

    No ratechanged toNo rate

    Held through RVU14B, RVU14C, RVU14D.

  16. January 1, 2013

    RVU13AR

    Earliest loaded release: No rate

    Held through RVU13B, RVU13C, RVU13D.

Rates in every CMS release
Effective fromOfficeFacilityCMS release
2026-10-01$44.91$44.91RVU26D
2026-07-01$44.91$44.91RVU26C
2026-04-01$44.91$44.91RVU26B
2026-01-01$44.91$44.91RVU26A
2025-10-01$45.05$45.05RVU25D
2025-07-01$45.05$45.05RVU25C
2025-04-01$45.05$45.05RVU25B
2025-01-01$45.05$45.05RVU25A
2024-10-01$46.67$46.67RVU24D
2024-07-01$46.67$46.67RVU24C
2024-04-01$46.67$46.67RVU24B
2024-03-09$46.67$46.67RVU24AR
2024-01-01$45.91$45.91RVU24A
2023-10-01$47.68$47.68RVU23D
2023-07-01$47.68$47.68RVU23C
2023-04-01$47.68$47.68RVU23B
2023-01-01$47.68$47.68RVU23A
2022-10-01$48.81$48.81RVU22D
2022-07-01$48.81$48.81RVU22C
2022-04-01$48.81$48.81RVU22B
2022-01-01$48.81$48.81RVU22A
2021-10-01$49.58$49.58RVU21D
2021-07-01$49.58$49.58RVU21C
2021-04-01$49.58$49.58RVU21B
2021-01-01$49.58$49.58RVU21A
2020-10-01$51.83$51.83RVU20D
2020-07-01$51.83$51.83RVU20C
2020-04-01$51.83$51.83RVU20B
2020-01-01$51.83$51.83RVU20A
2019-10-01$51.93$51.93RVU19D
2019-07-01$51.93$51.93RVU19C
2019-04-01$51.93$51.93RVU19B
2019-01-01$51.93$51.93RVU19A
2018-10-01$52.98$52.98RVU18D
2018-07-01$52.98$52.98RVU18C
2018-04-01$52.98$52.98RVU18B
2018-01-01$52.98$52.98RVU18AR1
2017-10-01$47.84$47.84RVU17D
2017-07-01$47.84$47.84RVU17C
2017-04-01$47.84$47.84RVU17B
2017-01-01$47.84$47.84RVU17A
2016-10-01$51.15$51.15RVU16D
2016-07-01$51.15$51.15RVU16C
2016-04-01$51.15$51.15RVU16B
2016-01-01$51.15$51.15RVU16A
2015-10-01$49.12$49.12RVU15D
2015-07-01$49.12$49.12RVU15C
2015-04-01$48.87$48.87RVU15B
2015-01-01$48.87$48.87RVU15A
2014-10-01Separate payment rules applySeparate payment rules applyRVU14D
2014-07-01Separate payment rules applySeparate payment rules applyRVU14C
2014-04-01Separate payment rules applySeparate payment rules applyRVU14B
2014-01-01Separate payment rules applySeparate payment rules applyRVU14A
2013-10-01Contractor-pricedContractor-pricedRVU13D
2013-07-01Contractor-pricedContractor-pricedRVU13C
2013-04-01Contractor-pricedContractor-pricedRVU13B
2013-01-01Contractor-pricedContractor-pricedRVU13AR

Price 88375 for an earlier date of service

Where the Delaware rate applies

Delaware is a Medicare payment area, not a city. Our Census mapping connects it to 79 cities and communities in Delaware. Some span more than one payment area; confirm with the service ZIP.

  • Arden
  • Ardencroft
  • Ardentown
  • Bear
  • Bellefonte
  • Bethany Beach
  • Bethel
  • Blades

Browse all communities in Delaware

88375 billing questions

Does 88375 include the equipment and image acquisition?

No. It represents the physician’s interpretation and report; a separate code covers the technical portion.

How does 88375 differ from 88376?

88375 reports interpretation and reporting of the images. 88376 covers the technical portion of optical endomicroscopy.

Is 88375 the same as a biopsy pathology examination?

No. It reports interpretation of optical endomicroscopy images, rather than microscopic examination of a removed tissue specimen.

What documentation supports reporting 88375?

Document the optical endomicroscopy images reviewed, the physician’s findings, and a report of the interpretation.

Can 88375 be reported with an endoscopy that uses optical endomicroscopy?

It may represent the interpretation service associated with an endoscopic study; the endoscopy code describes the procedure, while 88375 represents the image interpretation and report.

Where these rates come from

FeeBase calculates base physician payments from CMS work, practice-expense and malpractice RVUs, adjusted by each locality’s geographic indexes and the conversion factor. Services without a published rate are labeled, never given a made-up amount. Amounts are Medicare allowed amounts before claim adjustments: not a patient’s bill or a commercial rate.

CMS RVU26D · effective Oct 1, 2026 through the day before Jan 1, 2027

Show the CMS file lines behind this rate
RVUs for 88375PPRRVU2026_Oct_nonQPP.csv, line 11,313 (RVU26D)
Geographic factors for DelawareGPCI2026.csv, line 40 (RVU26D)

Open CMS sourceHow we calculate rates

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